Results 101 to 110 of about 8,783 (159)

Regulation of angiotensin II type 1 (AT1) receptor function

, 1999
The type 1 angiotensin receptor (AT(1)) mediates the important biological actions of the peptide hormone, angiotensin II (AngII), by activating an array of intracellular signaling pathways. The unique temporal arrangement and duration of AngII-stimulated
Thomas, Walter G.
core   +1 more source

Angiotensin converting enzyme and vascular endothelial growth factor responses to exercise training in claudicants: the role of ace inhibition

, 2009
Exercise training is well recognised as an effective treatment for intermittent claudication. The mechanism underlying exercise induced improvements is multi-factorial but remains poorly understood.
Ng, P.
core  

Angiotensin Ⅱ type 1 receptor autoantibody-AT1R-Bmal1 axis promotes phenotypic transition of vascular smooth muscle cells and vascular fibrosis

陆军军医大学学报
‍Objective‍　‍To investigate the mechanism by which angiotensin Ⅱ type 1 receptor autoantibody (AT1-AA) promotes phenotypic switch of vascular smooth muscle cells (VSMCs) and vascular fibrosis through abnormal expression of circadian clock protein BMAL1.
XUE Lingxia, LONG Yaolin, FENG Jiayan
doaj   +1 more source

Angiotensin converting enzyme and angiotensin II type 1-receptor gene polymorphisms and risk of ischaemic heart disease.

, 1999
OBJECTIVE: Polymorphisms in several genes of the renin-angiotensin system have been implicated as risk factors for myocardial infarction and ischaemic heart disease.
Rice, G I, Foy, C A, Grant, P J
core   +2 more sources

Sparsentan, a Dual Endothelin Type A and Angiotensin II Subtype 1 Receptor Antagonist for the Treatment of Immunoglobulin A Nephropathy: Latest Trial Results, Pharmacokinetic Considerations, and Binding Profile

Immunoglobulin A nephropathy (IgAN) is one of the most common forms of primary glomerulonephritis. In some patients, it can progress rapidly, leading to proteinuria, kidney failure, and death.
Eleanor Roberts
core   +1 more source

Determination of the exact molecular requirements for type 1 angiotensin receptor epidermal growth factor receptor transactivation and cardiomyocyte hypertrophy

, 2011
Major interest surrounds how angiotensin II triggers cardiac hypertrophy via epidermal growth factor receptor transactivation. G protein-mediated transduction, angiotensin type 1 receptor phosphorylation at tyrosine 319, and β-arrestin-dependent ...
Pearson, Richard B., Hannan, Ross D., Walter G. Thomas, Hongwei Qian, Allison M. Bourne, Hsiu-Wen Chan, Richard B. Pearson, Warner, Fiona J., Rebecca H. Ritchie, Chan, Hsiu-Wen, Hannan, Katherine M, Smith, Nicola J., Bourne, Allison M., Fiona J. Warner, Qian, Hongwei, Katherine M. Hannan, Thomas, Walter G., Nicola J. Smith, Ross D. Hannan, Ritchie, Rebecca H.   +19 more
core   +1 more source

Angiotensin type 2 receptor expression in kidney during angiotensin type 1 receptor blockade [PDF]

American Journal of Hypertension, 2002
openaire   +1 more source

Angiotensin II type 2 receptor agonist Compound 21 attenuates pulmonary inflammation in a model of acute lung injury

, 2018
Mario Menk, Jan Adriaan Graw, Clarissa von Haefen, Hendrik Steinkraus, Burkhard Lachmann, Claudia D Spies, David Schwaiberger Department of Anesthesiology and Operative Intensive Care Medicine, Charité – University Medicine Berlin ...
Steinkraus H, Lachmann B, Graw JA, Menk M, Spies CD, von Haefen C, Schwaiberger D   +6 more
core  

P2Y₂ Nucleotide Receptors Expressed Heterologously in Sympathetic Neurons Inhibit Both N-Type Ca²⁺ and M-Type K⁺ Currents

, 1998
The P2Y₂ receptor is a uridine/adenosine triphosphate (UTP/ATP)-sensitive G-protein-linked nucleotide receptor that previously has been reported to stimulate the phosphoinositide signaling pathway.
Webb, TE, Brown, DA, Barnard, EA, Filippov, AK   +3 more
core  

Angiotensin II Type 1 Receptor Blockers [PDF]

Value in Health, 2018
L Luan, H Hu, SC Li
openaire   +1 more source