Results 1 to 10 of about 75,534 (305)

Antiepileptic Drugs in Children

open access: yesÇocuk Dergisi, 2022
Antiepileptic drugs (AEDs) lead to seizure freedom in about 70% of all children with epilepsy. Appropriate drug selection is determined by the patient’s age, seizure semiology, epileptic syndrome, and pharmacogenetic approach.
Burçin Nazlı Karacabey   +2 more
doaj   +1 more source

Access to antiepileptic drug therapy in children in Camagüey Province, Cuba [PDF]

open access: yes, 2012
Objective: To describe access to antiepileptic drug therapy and estimate the prevalence of epilepsy in children in Camagüey Province, Cuba. Methods: All the community pharmacies in the province were visited and information collected about the number of ...
Acosta Nápolez, Maurilys   +7 more
core   +5 more sources

Safety and tolerability of antiepileptic therapy: emphasis on the use of valproates (literature review)

open access: yesРусский журнал детской неврологии, 2020
Since epilepsy is a chronic disease of the nervous system that requires long-term therapy and regular intake of antiepileptic drugs, good tolerability of therapy is crucial for the quality of life of these patients.
O. A. Pylaeva, K. Yu. Mukhin
doaj   +1 more source

Effect of oxidative stress on ABC transporters: contribution to epilepsy pharmacoresistance [PDF]

open access: yes, 2017
Epilepsy is a neurological disorder affecting around 1%-2% of population worldwide and its treatment includes use of antiepileptic drugs to control seizures. Failure to respond to antiepileptic drug therapy is a major clinical problem and over expression
Grewal, G. K.   +5 more
core   +2 more sources

Effects of Antiepileptic Drug Tapering on Episodic Memory as Measured by Virtual Reality Tests

open access: yesFrontiers in Neurology, 2020
Antiepileptic drugs impair episodic memory in patients with epilepsy, but this effect has so far only been examined with tests that do not provide first-person experience—an aspect that is crucial for episodic memory.
Yvonne Höller   +7 more
doaj   +1 more source

Antiepileptic drugs reduce serum uric acid [PDF]

open access: yes, 1987
Uric acid examination in 554 epileptic out-patients under long-term anticonvulsant medication revealed significantly lower serum concentrations compared to a group of normal controls.
Arab   +7 more
core   +1 more source

The pharmacogenetics antiepileptic drugs

open access: yesБюллетень сибирской медицины, 2008
There are some generalized data on a problem pharmacogenetics researches antiepileptic drugs on the basis of the analysis of the accessible native and foreign literature in this review.
N. A. Shnayder   +2 more
doaj   +1 more source

Short-term use of antiepileptic drugs is neurotoxic to the immature brain

open access: yesNeural Regeneration Research, 2015
Previous studies have shown that the long-term use of antiepileptic drugs can cause nervous system damage. However, short-term antiepileptic drug treatment is frequently given to infants, especially neonates, to control seizure.
Yu Liu   +4 more
doaj   +1 more source

Difficulties in Treatment and Management of Epilepsy and Challenges in New Drug Development

open access: yesPharmaceuticals, 2010
Epilepsy is a serious neurological disorder that affects around 50 million people worldwide. Almost 30% of epileptic patients suffer from pharmacoresistance, which is associated with social isolation, dependent behaviour, low marriage rates, unemployment,
Abdul Wahab
doaj   +1 more source

Long-term effect of antiepileptic drug switch on serum lipids and C-reactive protein. [PDF]

open access: yes, 2016
BACKGROUND: Prior studies have shown that switching patients from inducing antiepileptic drugs (AEDs) to lamotrigine, levetiracetam, or topiramate reduces serum lipids and C-reactive protein (CRP). These studies were all of short duration, and some drugs,
Chervoneva, Inna   +6 more
core   +2 more sources

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