Results 31 to 40 of about 497,334 (328)

Generation of virus-specific cytotoxic T cells in vitro I. Induction conditions of primary and secondary Sendai virus-specific cytotoxic T cells [PDF]

, 1979
H-2-restricted cytotoxic T cells specific for Sendai virus were generated in vitro in a primary response from normal mouse lymphocytes cultured in the presence of infective as well as inactivated Sendai virus. Antigen-presenting cells of different origin,
Andersson, Burakoff, Butchko, Cantor, Cantor, Cerottini, Cerottini, Dunlop, Engers, Engers, Ennis, Ertl, Ertl, Finberg, Gething, Hapel, Hayry, Julius, Jung, Kessel, Kirchner, Koszinowski, Koszinowski, Koszinowski, Lafferty, Levy, Lightbody, McKenzie, Palmer, Parker, Pfitzenmaier, Plate, Röllinghoff, Schrader, Shen, Simon, Wagner, Wagner, Wiktor, Zinkernagel, Zinkernagel, Zweerinck   +41 more
core   +1 more source

Generation of virus-specific cytotoxic T cells in vitro II. Induction requirements with functionally inactivated virus preparations [PDF]

, 1980
Using noninfectious Sendai virus preparations after selective enzymatic digestion of either of the two viral envelope glycoproteins, it was possible to study the effect of different virion-cell membrane interactions on virus-specific cytotoxic T ...
Bosslet, Braciale, Ennis, Ertl, Ertl, Finberg, Gething, Halloran, Hapel, Homma, Hosaka, Julius, Klenk, Koszinowski, Koszinowski, Koszinowski, Levy, Palmer, Pfitzenmaier, Rosenthal, Scheid, Schrader, Shimizu, Sugamura, Sugamura, Wiktor, Zinkernagel, Zweerink   +27 more
core   +1 more source

The ABCs of Antigen Presentation by Stromal Non-Professional Antigen-Presenting Cells [PDF]

International Journal of Molecular Sciences, 2021
Professional antigen-presenting cells (APCs), such as dendritic cells and macrophages, are known for their ability to present exogenous antigens to T cells. However, many other cell types, including endothelial cells, fibroblasts, and lymph node stromal cells, are also capable of presenting exogenous antigens to either CD8+ or CD4+ T cells via cross ...
Tom J. Harryvan, Sabine de Lange, Lukas J.A.C. Hawinkels, Els M.E. Verdegaal   +3 more
openaire   +3 more sources

Impact of Gold Nanoparticles on the Functions of Macrophages and Dendritic Cells

Cells, 2021
Gold nanoparticles (AuNPs) have demonstrated outstanding performance in many biomedical applications. Their safety is recognised; however, their effects on the immune system remain ill defined. Antigen-presenting cells (APCs) are immune cells specialised
Arindam K. Dey, Alexis Gonon, Eve-Isabelle Pécheur, Mylène Pezet, Christian Villiers, Patrice N. Marche   +5 more
doaj   +1 more source

Antigen presentation by Langerhans cells [PDF]

Current Opinion in Immunology, 2013
Langerhans cells and other skin-resident dendritic cells (DC) are required for the development of cutaneous adaptive immune responses. In vivo experiments using mice with selective DC-subset deficiencies and ex vivo experiments using isolated DC suggests that each subset makes a unique contribution to the adaptive response.
Daniel H. Kaplan, Botond Z. Igyártó
openaire   +3 more sources

Enhancement of the antigen-specific cytotoxic T lymphocyte-inducing ability in the PMDC11 leukemic plasmacytoid dendritic cell line via lentiviral vector-mediated transduction of the caTLR4 gene. [PDF]

, 2015
The aim of the present study was to enhance the efficiency of leukemia immunotherapy by increasing the antigen-specific cytotoxic T lymphocyte-inducing ability of leukemia cells. The leukemic plasmacytoid dendritic cell line PMDC05 containing the HLA-A02/
Bonehill, Aude, Hashimoto, Shigeo, Iwabuchi, Minami, Iwaya, Shunpei, Kasahara, Noriyuki, Narita, Miwako, Nishizawa, Yoshinori, Oiwa, Eri, Takahashi, Masuhiro, Takizawa, Jun, Uchiyama, Takayoshi   +10 more
core   +1 more source

The Antigen Presenting Cells Instruct Plasma Cell Differentiation

Frontiers in Immunology, 2014
The professional antigen presenting cells (APCs), including many subsets of dendritic cells and macrophages, not only mediate prompt but nonspecific response against microbes, but also bridge the antigen-specific adaptive immune response through antigen ...
Wei eXu, Jacques eBanchereau
doaj   +1 more source

Antigen-Specific Polyclonal Cytotoxic T Lymphocytes Induced by Fusions of Dendritic Cells and Tumor Cells [PDF]

, 2010
The aim of cancer vaccines is induction of tumor-specific cytotoxic T lymphocytes (CTLs) that can reduce the tumor mass. Dendritic cells (DCs) are potent antigen-presenting cells and play a central role in the initiation and regulation of primary immune ...
Gong, Jianlin, Hara, Eiichi, Homma, Sadamu, Koido, Shigeo, Namiki, Yoshihisa, Ohkusa, Toshifumi, Tajiri, Hisao   +6 more
core   +5 more sources

Langerhans cell homeostasis and activation is altered in hyperplastic human papillomavirus type 16 E7 expressing epidermis [PDF]

, 2015
It has previously been shown that expression of human papillomavirus type 16 (HPV) E7 in epidermis causes hyperplasia and chronic inflammation, characteristics of pre-malignant lesions.
Abd Warif, Nor Malia, Frazer, Ian H., Hibma, Merilyn H., Leggatt, Graham R., Mattarollo, Stephen R., Stoitzner, Patrizia   +5 more
core   +8 more sources

Recent Advances in Nanovaccines Using Biomimetic Immunomodulatory Materials

Pharmaceutics, 2019
The development of vaccines plays a vital role in the effective control of several fatal diseases. However, effective prophylactic and therapeutic vaccines have yet to be developed for completely curing deadly diseases, such as cancer, malaria, HIV, and ...
Veena Vijayan, Adityanarayan Mohapatra, Saji Uthaman, In-Kyu Park   +3 more
doaj   +1 more source