Results 21 to 30 of about 135,006 (287)

Foetal and neonatal alloimune thrombocytopenia as a rare exapmle of thrombocytopenia in newborn

Journal of Education, Health and Sport, 2018
Foetal and neonatal alloimmune thrombocytopenia (FNAIT) is caused by antigenic incompatibility of platelets between a pregnant woman and her child, resulting in producing antibodies by a mother against specific antigens (HPA- Human Platelet Antigens ...
Maciej Kamiński, Paulina Grzesik, Monika Długoń, Maciej Majsterek, Żaneta Kimber-Trojnar, Krzysztof Kamiński, Bożena Leszczyńska-Gorzelak   +6 more
doaj   +3 more sources

Molecular Genetics of Human Platelet Antigens

Transfusion Medicine and Hemotherapy, 1994
The purpose of this article is to review the molecular genetics of human platelet antigens, the application of molecular biological techniques to detect mutations underlying polymorphisms and the importance of these techniques for clinical medicine of immunemediated platelet destruction.
A.E.G.Kr. von dem Borne, S. Simsek
openaire   +3 more sources

Human platelet antigen allelic diversity in Peninsular Malaysia [PDF]

Immunohematology, 2016
Abstract Human platelet antigens (HPAs) are polymorphic and immunogenic glycoproteins encoded by biallelic genes on human chromosome 17 (HPA-1 to -4 and HPA-6 to -11), chromosome 5 (HPA-5), and chromosome 6 (HPA-15) and expressed on the surface of platelets.
Geoffrey K. Chambers, Zulkafli Zefarina, Mohd Nazri Hassan, Wan Ubaidillah Wan Syafawati, Zafarina Zafarina, Sundararajulu Panneerchelvam, Mohd Nor Norazmi, Hisham Atan Edinur   +7 more
openaire   +3 more sources

Frequency of human platelet antigens −1 to −5 and −15 in Turkmen blood donors

Advanced Biomedical Research, 2023
Background: Due to the presence of platelet antigen polymorphisms, human platelet membrane glycoproteins can be identified as an alloantigen or autoantigen.
Maedeh Nozarimirarkolaei, Maryam Dadashi, Ali Ghasemi, Shahram Samiee, Mojgan Shaeigan, Maryam Zadsar   +5 more
doaj   +1 more source

Unappreciated HLA Antibodies in Adult Immune Thrombocytopenic Purpura

Journal of the Formosan Medical Association, 2007
Immune thrombocytopenic purpura (ITP) is an autoimmune disease. Platelet refractoriness is frequently seen in patients with ITP. Platelets express platelet-specific antigens and human leukocyte antigens (HLA).
Jeong-Shi Lin, Jau-Yi Lyou, Ying-Ju Chen, Pei-Shan Chen, Hsueng-Mei Liu, Chao-Hung Ho, Tsung-Chi Hao, Cheng-Hwai Tzeng   +7 more
doaj   +1 more source

Human platelet antigen-3 polymorphism as a risk factor for rheumatological manifestations in hepatitis C

Revista da Sociedade Brasileira de Medicina Tropical, 2020
INTRODUCTION: Hepatitis C virus (HCV) infection is involved in the pathogenesis of autoimmune and rheumatic disorders. Although the human platelet antigens (HPA) polymorphism are associated with HCV persistence, they have not been investigated in ...
Natália Bronzatto Medolago, Adriana Camargo Ferrasi, Oswaldo Melo da Rocha, Maria Inês de Moura Campos Pardini, Rejane Maria Tommasini Grotto, Aline Faria Galvani, Giovanni Faria Silva   +6 more
doaj   +1 more source

Localization of platelet antigens in human kidney disease

Kidney International, 1980
The localization of a platelet antigen or antigens kidneys from 106 patients with renal disease was evaluated with immunofluorescent microscopy by using a rabbit antibody to human platelets. The antiplatelet IgG fixed to the surface membrane of platelets did not react with erythrocytes, leukocytes, plasma, normal kidney, or a variety of normal tissue ...
Alfred F. Michael, Kenneth E. Miller, Ian G. Dresner   +2 more
openaire   +3 more sources

A case report of neonatal alloimmune thrombocytopenia: The utility of platelet crossmatch studies in the diagnosis and management

Global Journal of Transfusion Medicine, 2019
Alloimmune thrombocytopenia is the most common cause of severe thrombocytopenia and intracranial bleed in the perinatal period, resulting from placental transfer of maternal platelet antibodies directed against the paternal-derived fetal platelet ...
H A Venkatesh, Abhishek Paul, Ambuja Kantharaj, Shivaram Chandrashekar   +3 more
doaj   +1 more source

Influence of platelet antigens differences between donor and recipient on neutropenia and thrombocytopenia duration after allogeneic stem cell transplantation

Онкогематология, 2022
Purpose: to study influence of platelet antigens system (HPA — Human Platelet Antigens) differences between donor and recipient on neutropenia and trombocytopenia duration after hematopoietic stem cells transplantation (HSCT).Materials and methods: 40 ...
L. L. Golovkina, R. M. Kutyina
doaj   +1 more source

Normal and pathological dynamics of platelets in humans [PDF]

Journal of Mathematical Biology volume 75, pages 1411-1462 (2017), 2016
We develop a comprehensive mathematical model of platelet, megakaryocyte, and thrombopoietin dynamics in humans. We show that there is a single stationary solution that can undergo a Hopf bifurcation, and use this information to investigate both normal and pathological platelet production, specifically cyclic thrombocytopenia.
arxiv   +1 more source