Results 31 to 40 of about 44,629 (299)

Tumor-associated Carbohydrate Antigens: Sialyl Le^a and T/Tn Antigens in Canine Mammary Tumors [PDF]

Veterinary Pathology, 2009
Twenty-eight canine mammary tubulopapillary carcinomas and 14 simple adenomas were studied by immunohistochemistry for the expressions of the tumor-associated carbohydrate antigens. Sialyl Lea was detected in 71.42% of the malignant and 92.84% of the benign tumors.
M, Nowak, J, Madej, P, Dziegiel, W, Lopuszynski, A, Rodo, M, Ugorski   +5 more
openaire   +2 more sources

Carbohydrate antigen 15-3 as a marker of disease severity in patients with chronic hypersensitivity pneumonitis* [PDF]

Jornal Brasileiro de Pneumologia
Objective: Biomarkers associated with mucin 1, such as Krebs von den Lungen-6 and carbohydrate antigen (CA) 15-3, are increased in various interstitial lung diseases.
Paula Silva Gomes, Maria Raquel Soares, Maria Fernanda Munhoz Lages Marchenta, Gustavo de Souza Portes Meirelles, Rimarcs Gomes Ferreira, André Bezerra Botelho, Rafaela Boaventura Martins, Carlos Alberto de Castro Pereira   +7 more
doaj   +4 more sources

Tumor derived Microvesicles enhance cross-processing ability of clinical grade Dendritic Cells [PDF]

, 2018
Tumor cells release extracellular microvesicles (MVs) in the microenvironment to deliver biological signals to neighbouring cells as well as to cells in distant tissues.
Battisti, Federico, Belleudi, Francesca, Claudia De Archangelis,, DI FILIPPO, Alessandra, Dionisi, Marco, Napoletano, Chiara, Nuti, Marianna, RAHIMI KOSHKAKI, Hassan, Rughetti, Aurelia, Ruscito, Ilary, Torrisi, Maria Rosaria, Zizzari, ILARIA GRAZIA   +11 more
core   +1 more source

Prognostic and therapeutic significance of carbohydrate antigen 19-9 as tumor marker in patients with pancreatic cancer [PDF]

, 2006
In pancreatic cancer ( PC) accurate determination of treatment response by imaging often remains difficult. Various efforts have been undertaken to investigate new factors which may serve as more appropriate surrogate parameters of treatment efficacy ...
Anderson JS, Bekaii-Saab TS, Brambs HJ, Burris HA, Ebrahimi B, Glenn J, Gogas H, Goggins M, Heinemann V, Heinemann V, Heinemann V, Ishii H, Jamieson NB, Jiang XT, Katz A, Ko AH, Koprowski H, Louvet C, Lundin J, Maisey NR, Montgomery RC, Moore MJ, Ni XG, Okusaka T, Petra Stieber, Philip PA, Ralf Wilkowski, Saad ED, Safi F, Safi F, Sakar B, Sawaki A, Sperti C, Stathopoulos GP, Stefan Boeck, Stefan Holdenrieder, Steinberg W, Tanaka N, Tempero MA, Tian F, van Custem E, Vimalachandran D, Volker Heinemann, Wilkowski R, Wilkowski R, Wilkowski R, Willet CG, Wolff RA, Ziske C   +48 more
core   +1 more source

Tobacco Mosaic Virus as a New Carrier for Tumor Associated Carbohydrate Antigens [PDF]

Bioconjugate Chemistry, 2012
Tumor-associated carbohydrate antigens (TACAs) are being actively studied as targets for antitumor vaccine development. One serious challenge was the low immunogenecity of these antigens. Herein, we report the results of using the tobacco mosaic virus (TMV) capsid as a promising carrier of a weakly immunogenic TACA, the monomeric Tn antigen. The copper(
Yin, Zhaojun, Nguyen, Huong Giang, Chowdhury, Sudipa, Bentley, Philip, Bruckman, Michael A., Miermont, Adeline, Gildersleeve, Jeffrey C., Wang, Qian, Huang, Xuefei   +8 more
openaire   +3 more sources

Conjugate Vaccines Targeting Tumor-Associated Carbohydrate Antigens

Vaccines
The surface of cancer cells is covered in abnormal carbohydrate antigens that facilitate tumor growth, immune evasion and metastasis. Overexpressed and often specific to cancer cells, these tumor-associated carbohydrate antigens (TACAs) offer a valuable ...
Nadine Rosenglick, Géraud Valentin, Kiran Marineni, Euclydes P. Neto, Peter R. Andreana   +4 more
doaj   +1 more source

Synthesis of N-Glycolylneuraminic Acid (Neu5Gc) and Its Glycosides. [PDF]

, 2019
Sialic acids constitute a family of negatively charged structurally diverse monosaccharides that are commonly presented on the termini of glycans in higher animals and some microorganisms.
Chen, Xi, Kooner, Anoopjit Singh, Yu, Hai   +2 more
core   +2 more sources

Expression analysis of carbohydrate antigens in ductal carcinoma in situ of the breast by lectin histochemistry

BMC Cancer, 2008
Background The number of breast cancer patients diagnosed with ductal carcinoma in situ (DCIS) continues to grow. Laboratory and clinical data indicate that DCIS can progress to invasive disease.
Kieber-Emmons Thomas, Siegel Eric, Korourian Soheila, Monzavi-Karbassi Behjatolah   +3 more
doaj   +1 more source

MGL‐Based Drug Conjugate: A Novel Glycan‐Targeting Strategy for Potential Precision Cancer Therapy

ChemistryEurope
Cancer remains a major cause of mortality, especially in advanced stages where current therapies are less effective. Antibody‐drug conjugates offer targeted treatment, but their efficacy is limited by on‐target/off‐tumor toxicity since most protein ...
Carlos D. L. Lima, Rafaela Abrantes, Victor Lorrain, Joana Gomes, Reyes Núñez‐Franco, João P. M. António, Catarina Gomes, Ana Gimeno, Benedita A. Pinheiro, Angelina S. Palma, Jesús Jiménez‐Barbero, Pedro M. P. Gois, Gonzalo Jiménez‐Osés, Sandra J. van Vliet, Celso A. Reis, Filipa Marcelo   +15 more
doaj   +2 more sources

Alternative antibody for the detection of CA19-9 antigen: a European multicenter study for the evaluation of the analytical and clinical performance of the Access (R) GI Monitor assay on the UniCel (R) Dxl 800 Immunoassay System [PDF]

, 2008
Background: Gastrointestinal cancer antigen CA19-9 is known as a valuable marker for the management of patients with pancreatic cancer. Methods: The analytical and clinical performance of the Access(R) GI Monitor assay (Beckman Coulter) was evaluated on ...
Barone D, Bekaii-Saab TS, Dittadi R, Gogas H, Heinemann V, Ishii H, Jiang XT, Magnani JL, Micke O, Molina R, Reiter W, Reiter W, Safi F, Steinberg W, Tempero MA, Wang WS   +15 more
core   +3 more sources