Results 51 to 60 of about 2,581 (172)

Synthesis, Electrochemistry, In Vitro Antiprotozoal Efficacy and Mechanistic Study of Novel ‘Ferrantoin’ and Related Derivatives

Applied Organometallic Chemistry, Volume 40, Issue 7, July 2026.
1,2‐Disubstituted ferrocene analogues bearing hydantoin or rhodanine synthons were synthesised and assessed for antitrypanosomatid activity. An antileishmanial early lead, analogue 23, acting through ROS generation and hence oxidative stress, was uncovered.
Maryna Saayman, Janine Aucamp, Helena D. Janse van Rensburg, Christina Kannigadu, Rotondwa Mphephu, Andrew J. Swarts, Keisuke Suganuma, David D. N'Da   +7 more
wiley   +1 more source

Potential anti-HIV and antitrypanosomal components revealed in Sorindeia nitidula via LC-ESI-QTOF-MS/MS

Scientific Reports
Sorindeia nitidula (Anacardiaceae) is used by traditional practitioners to treat influenza illnesses with cephalgia and febrile aches. However, the potential active ingredients for its remarkable antioxidant, anti-HIV and antitrypanosomal activities ...
Guy Roland Ebede, Emeka Emea Okoro, Josephine Ngo Mbing, Patrick Herve Diboue Betote, Dieudonne Emmanuel Pegnyemb, Muhammad Iqbal Choudhary, Xavier Siwe-Noundou, Joseph Thierry Ndongo   +7 more
doaj   +1 more source

ANTI-TRYPANOSOMAL EFFECTS O7F SOME SELECTED NIGERIAN MEDICINAL PLANTS

Academy Journal of Science and Engineering
Treatments of African trypanosomiasis have been dependent on the use of synthetic drugs which have several drawbacks. This is compounded by the emergence of drug-resistant parasites.
Enimie Endurance Oaikhena, Yahaya Umar, Vantsawa Philip, Ibeh Onyinye   +3 more
doaj   +1 more source

Study of the <em>in Vitro</em> Antiplasmodial, Antileishmanial and Antitrypanosomal Activities of Medicinal Plants from Saudi Arabia

Molecules, 2012
The present study investigated the <em>in vitro</em> antiprotozoal activity of sixteen selected medicinal plants. Plant materials were extracted with methanol and screened <em>in vitro</em> against erythrocytic schizonts of <em&
Nawal M. Al-Musayeib, Ramzi A. Mothana, Shaza Al-Massarani, An Matheeussen, Paul Cos, Louis Maes   +5 more
doaj   +1 more source

Exploring 6‐Hydroxy‐3‐Aryl/Heteroarylcoumarins as Promising Candidates Against Trypanosoma cruzi

ChemMedChem, Volume 21, Issue 9, 14 May 2026.
New therapies are urgently needed for Chagas disease, and screening of 6‐hydroxy‐3‐aryl/heteroarylcoumarin derivatives identified highly selective compounds with potent activity against T. cruzi. In particular, derivative 1f showed submicromolar trypomastigote potency, dual‐stage activity, and inhibition of amastigote‐to‐trypomastigote differentiation,
C. N. Pereira, L. da Silva Lara, S. da Costa Lanera, T. Pérez de Souza, M. C. de Souza Pereira, G. L. Delogu, M. Silva dos Santos, M. J. Matos   +7 more
wiley   +1 more source

Chemical Profiling and Biological Screening of Some River Nile Derived-Microorganisms

Frontiers in Microbiology, 2019
AimsChemical and biological studies of the River Nile derived-microorganisms are limited. Hence, this work was carried out to screen the River Nile habitat.
Momen M. Lotfy, Hossam M. Hassan, Hossam M. Hassan, Rabab Mohammed, Mona Hetta, Ahmed O. El-Gendy, Mostafa E. Rateb, Mostafa E. Rateb, Mohamed A. Zaki, Noha M. Gamaleldin, Noha M. Gamaleldin   +10 more
doaj   +1 more source

Manganese Porphyrin‐Catalyzed One‐Pot Oxidation of Lupeol: Efficient Conversion of Its Terminal Alkene Into Carboxylic Acids

Chemistry &Biodiversity, Volume 23, Issue 5, May 2026.
Manganese porphyrin catalyst enables green PhI(OAc)2 oxidation of lupeol in ethyl acetate, achieving 94% conversion and the formation of eight products, including selective C20 olefin transformations and one‐pot conversion of the isopropenyl group to carboxylic acids, all without the need of C3‐OH protection step.
Leila Renan Oliveira, Pedro Fonseca‐Pinheiro, Lucienir Pains Duarte, Diogo Montes Vidal, Grasiely Faria de Sousa, Dayse Carvalho da Silva Martins   +5 more
wiley   +1 more source

Chemical Composition and Biological Activities of Artemisia pedemontana subsp. assoana Essential Oils and Hydrolate

Biomolecules, 2019
Given the importance of the genus Artemisia as a source of valuable natural products, the rare plant Artemisia pedemontana subspecies assoana, endemic to the Iberian Peninsula, has been experimentally cultivated in the greenhouse and aeroponically, to ...
Paula Sainz, María Fe Andrés, Rafael A. Martínez-Díaz, María Bailén, Juliana Navarro-Rocha, Carmen E. Díaz, Azucena González-Coloma   +6 more
doaj   +1 more source

Antitrypanosomal and Anthelminthic Properties of Ethanol Extracts of Carica papaya Linn. and Ceiba pentandra (L) Gaertn.

Journal of Chemistry, 2022
The most common diseases that affect low-income countries are helminthosis and trypanosomosis. In Ghana, and in many other African countries, herbal treatment of various diseases is still common.
Ahmed Wahab Obeng, Yaw Duah Boakye, Theresa Appiah Agana, Vivian Etsiapa Boamah, James Oppong-Kyekyeku, Abena Amponsaa Brobbey, Francis Adu, Stephen Yao Gbedema, Christian Agyare   +8 more
doaj   +1 more source

Rhenium Complexes as Antimicrobial Agents

Helvetica Chimica Acta, Volume 109, Issue 5, May 2026.
Rhenium complexes are stepping into the fight against superbugs. Our new review explores how these metallic complexes could inspire the next generation of antimicrobial therapies. ABSTRACT The escalating crisis of antimicrobial resistance (AMR) necessitates the exploration of unconventional therapeutic scaffolds.
Fabio Zobi, Gozde Demirci, Marija Rasic
wiley   +1 more source