Improvement in Outcomes with a New Bedaquiline-based Regimen in Postoperative Cases of Drug-resistant Tuberculosis of the Spine: A Case Series [PDF]
Journal of Clinical and Diagnostic ResearchThe incidence of drug-resistant strains of Tuberculosis (TB) is rising at an alarming rate. With the emergence of newer drug-resistant strains, managing the disease with existing antitubercular agents is becoming increasingly difficult. Few studies exist
Soutrik Kundu, Sarvan Singh
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Synthesis of Quinazoline and Quinazolinone Derivatives via Ligand-Promoted Ruthenium-Catalyzed Dehydrogenative and Deaminative Coupling Reaction of 2-Aminophenyl Ketones and 2-Aminobenzamides with Amines [PDF]
, 2019 The in situ formed ruthenium catalytic system ([Ru]/L) was found to be highly selective for the dehydrogenative coupling reaction of 2-aminophenyl ketones with amines to form quinazoline products.
Arachchige, Pandula T. Kirinde +1 more
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A facile synthesis of novel indole derivatives as potential antitubercular agents
Journal of Taibah University for Science, 2017 A novel series of 5,5-dimethyl-11-phenyl-4b,5,5a,10,10a,11,11a,12-octahydro-10,11,12-triaza-indeno[2,1-b]fluorenes 3aâ3l were prepared by reacting oxindole, aryl amines and acetone using dibutylamine as an organocatalyst via simultaneous Knoevenagel ...
Gulzar A. Khan +5 more
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A Multinational Analysis of Mutations and Heterogeneity in PZase, RpsA, and PanD Associated with Pyrazinamide Resistance in M/XDR Mycobacterium tuberculosis. [PDF]
, 2017 Pyrazinamide (PZA) is an important first-line drug in all existing and new tuberculosis (TB) treatment regimens. PZA-resistance in M. tuberculosis is increasing, especially among M/XDR cases.
Catanzaro, A +7 more
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Synthesis of Some 4-Thiazolidinone Derivatives as Antitubercular Agents [PDF]
Journal of Sciences, Islamic Republic of Iran, 2004 Substituted Schiff's bases 2a-o prepared by the treatment of 2-amino-4-(?-methoxyiminocarbomethoxymethyl)-thiazole 1 with different aromatic aldehydes, on cyclocondensation with mercaptoaceticacid and mercaptopropionicacid in dry benzene furnished ...
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Osteoarticular Tuberculosis: a Secondary Manifestations to Tuberculous Pleural Effusion [PDF]
, 2014 Tuberculosis appears to be increasing throughout the world after years of continuous decline, despite the introduction of effective chemotherapy. This resurgence is related to the increasing number of patients immunocompromised by chemotherapeutic agents
Rumende, C. M. (Cleopas) +2 more
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Identification of Axinellamines A and B as Anti-Tubercular Agents
Marine DrugsTuberculosis remains a significant global health pandemic. There is an urgent need for new anti-tubercular agents to combat the rising incidence of drug resistance and to offer effective and additive therapeutic options.
Emily J. Strong +5 more
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Second-line antitubercular agents and their adverse effects [PDF]
Vojnosanitetski Pregled, 2006 Nagorni-Obradović Ljudmila +1 more
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The Korean Journal of Gastroenterology, 2016 Anti-tuberculosis drugs can produce levels of hepatotoxicity ranging from mild elevation of aminotransferase to severe acute hepatitis. A few cases of drug-induced autoimmune hepatitis or the drug reaction with eosinophilia and systemic symptom (DRESS ...
Joon Hyuk Choi +6 more
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