Results 31 to 40 of about 20,345 (152)
Colo‐appendico‐duodenal fistula: Rare presentation of extrapulmonary tuberculosis
Clinical Case Reports, 2021 A colo‐appendico‐duodenal fistula is a rare occurrence that results from extrapulmonary tuberculosis (TB) complications, especially in the endemic region.
David Eng Yeow Gan +3 more
doaj +1 more source
Mapping and characterization of G-quadruplexes in Mycobacterium tuberculosis gene promoter regions [PDF]
, 2017 Mycobacterium tuberculosis is the causative agent of tuberculosis (TB), one of the top 10 causes of death worldwide in 2015. The recent emergence of strains resistant to all current drugs urges the development of compounds with new mechanisms of action ...
Lavezzo, Enrico +7 more
core +1 more source
Synthesis and Antitubercular Evaluation of Some Novel 1,2,3,6-tetrahydropyrimidine-5-carbonitrile [PDF]
, 2013      In an attempt to find a new class of antitubercular agents, a series of 1,2,3,6-tetrahydropyrimidine-5-carbonitrile were prepared via the reaction of ethyl N-ethoxycarbonylbenzimidate 2a-b with cyanoacetanilide derivatives 1a-c.
Boukthir, Mouna +4 more
core +1 more source
Multitargeting Compounds: A Promising Strategy to Overcome Multi-Drug Resistant Tuberculosis [PDF]
, 2020 Tuberculosis is still an urgent global health problem, mainly due to the spread of multi-drug resistant M. tuberculosis strains, which lead to the need of new more efficient drugs.
Chiarelli, Laurent Roberto +2 more
core +1 more source
Chemistry Central Journal, 2018 Background The study describes the synthesis, characterization, in vitro antimicrobial and anticancer evaluation of a series of 2-(1-benzoyl-1H-benzo[d]imidazol-2-ylthio)-N-substituted acetamide derivatives. The synthesized derivatives were also assessed
Snehlata Yadav +6 more
doaj +1 more source
Synthesis, and biological screening of chloropyrazine conjugated benzothiazepine derivatives as potential antimicrobial, antitubercular and cytotoxic agents [PDF]
, 2020 A series of twenty new chloropyrazine conjugated benzothiazepines (22-41) have been synthesized with 58%–95% yields. The compounds were characterized by using different spectroscopic techniques including FT-IR, ¹H NMR, ¹³C NMR spectroscopy and mass ...
Bhandare, R. R. +11 more
core +1 more source
Indonesian Journal of Chemistry, 2022 Two series of new 3,5-disubstituted-pyrazole-1-carbothioamides (4a-f and 5a-e) were designed and synthesized through condensation reaction between chalcones and thiosemicarbazides under alkaline condition via cyclocondensation reaction.
Kok Tong Wong +6 more
doaj +1 more source
Effect of α-tocopherol on antitubercular drugs induced hepatotoxicity [PDF]
, 2016 Background: Mycobacterium, the causative organism of tuberculosis, is notorious for its ability to develop resistance with monotherapy. To prevent emergence of resistance, combination of antitubercular drugs is given for months to years that can lead to ...
Nehra, Manju +3 more
core +2 more sources
Synthesis and Evaluation of the 2-Aminothiazoles as Anti-Tubercular Agents. [PDF]
PLoS ONE, 2016 The 2-aminothiazole series has anti-bacterial activity against the important global pathogen Mycobacterium tuberculosis. We explored the nature of the activity by designing and synthesizing a large number of analogs and testing these for activity against
Edward A Kesicki +12 more
doaj +1 more source
International Archives of Otorhinolaryngology, 2023 Introduction Tuberculosis is a disease of diversified presentation. It affects almost all organs in the body, and otorhinolaryngological, head and neck involvement is not an exception.
Biban Chhabra +4 more
doaj +1 more source