Results 51 to 60 of about 22,631 (229)

Development of Pseudomembranous Colitis Four Months after Initiation of Rifampicin

Case Reports in Gastroenterology, 2011
Pseudomembranous colitis (PMC) may develop with long-term antibiotic administration, but is rarely reported to be caused by antitubercular agents. We present a case of PMC that occurred 120 days after starting rifampicin.
Jeong Moon Choi, Hyung Hun Kim, Seun Ja Park, Moo In Park, Won Moon   +4 more
doaj   +1 more source

Design, Synthesis, and Anti-mycobacterial Evaluation of New 3,5-Disubstituted-pyrazole-1-carbothioamides

Indonesian Journal of Chemistry, 2022
Two series of new 3,5-disubstituted-pyrazole-1-carbothioamides (4a-f and 5a-e) were designed and synthesized through condensation reaction between chalcones and thiosemicarbazides under alkaline condition via cyclocondensation reaction.
Kok Tong Wong, Hasnah Osman, Thaigarajan Parumasivam, Muhammad Solehin Abd Ghani, Mohd. Zaheen Hassan, Unang Supratman, Mohamad Nurul Azmi Mohamad Taib   +6 more
doaj   +1 more source

Design, synthesis, biological evaluation, and computational insights of 2-(Aryl)benzo[d]imidazo[2,1-b]thiazole-7-sulfonamide derivatives as potent antitubercular and antibacterial agents. [PDF]

BMC Chem
Deshmukh HS, Adole VA, Mali SN, Jagdale BS.   +3 more
europepmc   +2 more sources

Attenuation of Mycobacterium species through direct and macrophage mediated pathway by unsymmetrical diaryl urea [PDF]

, 2016
Tuberculosis is a major threat for mankind and the emergence of resistance strain of Mycobacterium tuberculosis (Mtb) against first line antibiotics makes it lethal for human civilization.
Charan Raja, Mamilla R., Datta, Dhrubajyoti, Debnath, Joy, Franzblau, Scott G., Gramajo, Hugo Cesar, Halloum, Iman, Kar Mahapatra, Santanu, Kremer, Laurent, Tsai, Yi Ting, Velappan, Anand Babu, Wan, Baojie   +10 more
core   +1 more source

Synthesis and Evaluation of the 2-Aminothiazoles as Anti-Tubercular Agents. [PDF]

PLoS ONE, 2016
The 2-aminothiazole series has anti-bacterial activity against the important global pathogen Mycobacterium tuberculosis. We explored the nature of the activity by designing and synthesizing a large number of analogs and testing these for activity against
Edward A Kesicki, Mai A Bailey, Yulia Ovechkina, Julie V Early, Torey Alling, Julie Bowman, Edison S Zuniga, Suryakanta Dalai, Naresh Kumar, Thierry Masquelin, Philip A Hipskind, Joshua O Odingo, Tanya Parish   +12 more
doaj   +1 more source

Incidence, Diagnosis and Treatment of Otorhinolaryngological, Head and Neck Tuberculosis: A Prospective Clinical Study

International Archives of Otorhinolaryngology, 2023
Introduction Tuberculosis is a disease of diversified presentation. It affects almost all organs in the body, and otorhinolaryngological, head and neck involvement is not an exception.
Biban Chhabra, Pratibha Vyas, Priyanshi Gupta, Prateek Sharma, Kanika Sharma   +4 more
doaj   +1 more source

Phenothiazines as a solution for multidrug resistant tuberculosis: From the origin to present [PDF]

, 2015
Historically, multiplicity of actions in synthetic compounds is a rule rather than exception. The science of non-antibiotics evolved in this background.
Debalina Sinha Roy, Jette E. Kristiansen, Jørn B. Christensen, Oliver Hendricks, Shauroseni Palchoudhuri, Sujata G. Dastidar, Sukhen Das   +6 more
core   +6 more sources

Quinoxaline Moiety: A Potential Scaffold against Mycobacterium tuberculosis

Molecules, 2021
Background. The past decades have seen numerous efforts to develop new antitubercular agents. Currently, the available regimens are lengthy, only partially effective, and associated with high rates of adverse events. The challenge is therefore to develop
Marc Montana, Vincent Montero, Omar Khoumeri, Patrice Vanelle   +3 more
doaj   +1 more source

The Relationship Between Aldose Reductase and Isoxazole Derivatives: An In Vitro and In Silico Approach to Its Correlation With Diabetic Conditions

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Diabetes mellitus (DM), which can result in a number of problems such as cataracts, neuropathy, retinopathy, nephropathy, and several cardiovascular illnesses, continues to be a growing issue despite major advancements in treatment approaches.
Ahmet Esat Göner, Hatice Esra Duran
wiley   +1 more source

Synthesis, Antimycobacterial Activity, and Computational Insight of Novel 1,4‐Benzoxazin‐2‐one Derivatives as Promising Candidates against Multidrug‐Resistant Mycobacterium Tuberculosis

ChemMedChem, EarlyView.
A series of 14 novel 1,4‐benzoxazinone derivatives is tested against various strains of Mycobacterium tuberculosis. All compounds show high activity against all tested strains, particularly the resistant strains. Additionally, the novel derivatives exhibit low cytotoxicity toward mammalian Vero cells.
Maria Grazia Mamolo, Emanuele Carosati, Diletta Pasin, Alessandro De Logu, Gianluigi Cabiddu, Marko Jukič, Daniele Zampieri   +6 more
wiley   +1 more source