Results 131 to 140 of about 24,501 (255)

Phase coupling between eye and brain pulsations is bidirectional and modulated by the parasympathetic system – An fMREye study

Acta Ophthalmologica, EarlyView.
Abstract Purpose Physiological pulsations driven by cardiac, respiratory, and vasomotor activity are essential for solute transport within perivascular and perineural cerebrospinal fluid (CSF) pathways that support brain and eye clearance systems. Previous studies have shown that parasympathetic blockade significantly reduces ocular pulsation power and
Ebrahimi Seyed‐Mohsen, Väyrynen Tommi, Huotari Niko, Saarela Ville, Honkamo Marja, Helakari Heta, Järvelä Matti, Korhonen Vesa, Raitamaa Lauri, Kiviniemi Vesa   +9 more
wiley   +1 more source

Opsoclonus‐Myoclonus‐Ataxia Revealing Underlying Neuromyelitis Optica Spectrum Disorder

Movement Disorders Clinical Practice, EarlyView.
Ana Silvia Sobreira Lima Verde, Flávia de Paiva Santos Rolim, Amanda Vale Catunda, José Orlando Ferreira Tomé Filho, Milena Sales Pitombeira, Fernanda Martins Maia Carvalho, Paula Camila Alves de Assis Pereira Matos   +6 more
wiley   +1 more source

The immunological landscape of the area postrema in neuromyelitis optica spectrum disorders

Brain Pathology, EarlyView.
Aquaporin‐4 antibody‐positive neuromyelitis spectrum disorder is characterized by large tissue destructive lesions in medulla, spinal cord, and optic nerves, with only partial recovery from clinical symptoms, and by lesions with very little tissue destruction and mostly complete recovery from clinical symptoms, as seen in the area postrema ...
Qian Yu, Yoshiki Takai, Naoya Yamazaki, Sarah Brandl, Katharina M. Mair, Thibault Bouderlique, Maria Eleni Kastriti, Igor Adameyko, Romana Höftberger, Markus Reindl, Jan Bauer, Monika Bradl   +11 more
wiley   +1 more source

Different staining patterns of NMO-IgG in M-1 and M-23 AQP4 transfected cells.

, 2013
Anti-AQP4 IgG (red) in NMO patient's serum targets AQP4 (green), which is expressed by transiently transfected HEK cells. Performing the assay for M-23 AQP4 (A, green) versus M-1 AQP4 (B, green), results in different staining patterns of NMO-IgG (red ...
Bettina Kuenz (89551), Fahmy Aboul-Enein (351477), Franziska Di Pauli (365013), Sven Jarius (25658), Maria K. Storch (365016), Wolfgang Kristoferitsch (351482), Markus Reindl (89559), Andreas Lutterotti (89552), Thomas Berger (72614), Simone Mader (365012), Michael Khalil (365015), Kathrin Schanda (365014)   +11 more
core   +1 more source

AQP4 and HIVAN

Experimental and Molecular Pathology, 2018
Fahad, Mubariz, Joseph L, Bryant, Vamshi K C, Nimmagadda, Jayanta, Ray, Tapas K, Makar   +4 more
openaire   +2 more sources

Nissl’s staining of AQP4^+/+ and AQP4^−/− mice.

, 2013
Injection of rhVEGF165 intracerebroventricularly had no effect on Nissl’s staining in normal mice. At the three time points, marked neuron loss perihemotoma were found in AQP4−/− mice when compared to AQP4+/+ mice.
Yuping Tang (249674), Qiang Dong (380835), Heling Chu (425189)   +2 more
core   +1 more source

Inborn errors of immunity in children with neuroinflammation

Developmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu, Dilan Dissanayake, Jessie Cunningham, Helen Branson, Ori Scott, E Ann Yeh   +5 more
wiley   +1 more source

2,6-diaminopurine enhances Aqp4 stop codon readthrough and AQP4 perivascular localization in the brain

In the brain, the water channel Aquaporin 4 (AQP4) is largely restricted to astrocytes, enriched at perivascular astrocytic processes, and involved in fluid balance and neurological disease. The perivascular pool is functionally unique as it is depolarized in diseases, targeted by neuromyelitis optica autoantibodies, and implicated in the clearance of ...
Darshan Sapkota, Sadan Dahal, Ezzeldin Nasser Attia Elhawary, Prarthana Suresh, Zhan Shi, Hamza Lalami, Alyssa Le   +6 more
openaire   +1 more source

Rethinking diabetic retinopathy: Homeostatic mechanisms for retinal clearance

Diabetic Medicine, EarlyView.
In the healthy retina, balanced production and clearance of metabolic waste and fluid maintain retinal homeostasis and normal visual function. Diabetes disrupts this balance, increasing the accumulation of metabolic waste products, including advanced glycation end products (AGEs) and advanced lipoxidation end products (ALEs), while impairing waste and ...
Karis Little, Judith Lechner, Giulia De Rossi, Tara Cullen, Jennifer Perais, Eleni Beli, Noemi Lois, Alan W. Stitt   +7 more
wiley   +1 more source

Neuroprotective Role of AQP4 Knockdown in Astrocytes After Oxygen–Glucose Deprivation

Brain and Behavior
Background Aquaporin‐4 (AQP4), predominantly expressed in astrocytes, has been implicated in the development of brain edema following ischemic events. However, its role in post‐stroke neuroinflammation is not fully understood.
Xin Xing, Shuyan Zhang
doaj   +1 more source