Results 71 to 80 of about 23,657 (257)

“Low‐Positive” MOG‐IgG Cases Among Adults With a First Event Suggestive of Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the prevalence and clinical characteristics of patients with “low‐positive” (LP) MOG‐IgG (titres 1:160–1:320) among adults with a first demyelinating event (FDE) suggestive of multiple sclerosis (MS). Methods From the Barcelona CIS inception cohort, we included adult patients with serum collected ≤ 6 months from the FDE.
Javier Villacieros‐Álvarez, Carmen Espejo, Georgina Arrambide, Mireia Castillo, Marta Rodriguez, Helena Ariño, Iker Elosua, Carmen Tur, Angela Vidal‐Jordana, Andreu Vilaseca, Joaquín Castilló, Ingrid Galán, Luciana Midaglia, Carlos Nos, Breogan Rodríguez‐Acevedo, Ana Zabalza, Luca Bollo, Agustín Pappolla, René Carvajal, Neus Mongay‐Ochoa, Jordi Rio, Jaume Sastre‐Garriga, Manuel Comabella, Gesualdina Busiello, Sofia Sceppacuercia, Àlex Rovira, Xavier Montalban, Mar Tintoré, Cristina Auger, Álvaro Cobo‐Calvo   +29 more
wiley   +1 more source

Immunoreactivity against AQP4 (red) and GFAP (green).

, 2013
(A) In human glioblastoma tissue AQP4 (red) shows an intensive staining whereas in primary cell culture of this glioblastoma AQP4 could not be detected (B). (C) Primary cell culture of astrocytes stained for AQP4.
Karen Wolburg-Buchholz (323517), Susan Noell (294230), Hartwig Wolburg (185538), Petra Fallier-Becker (323518), Rainer Ritz (294227)   +4 more
core   +1 more source

Role of AQP4 in skeletal muscle

Proceedings for Annual Meeting of The Japanese Pharmacological Society, 2018
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Frigeri, Antonio, Paola, Nicchia G
openaire   +3 more sources

Evaluation of Dried Plasma Spot‐Based Quantification of Glial Fibrillary Acidic Protein as a Disease‐Associated Biomarker in Neuromyelitis Optica Spectrum Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab, Evelyn Alvarez, Roua Hamdi, Bingqing Zhang, Hayeun Ji, Niyati Jhaveri, Patrick Schindler, Pedro Sanchez, Pia S. Sperber, Tanja Schmitz‐Hübsch, Frederike C. Oertel, Nisa Vorasoot, Najib Kissani, Falko Böhringer, Jens Kuhle, Anne‐Katrin Pröbstel, Xiao‐Jun Ma, Péter Körtvelyessy, Patrick Waters, Friedemann Paul   +19 more
wiley   +1 more source

Immunodominant T cell determinants of aquaporin-4, the autoantigen associated with neuromyelitis optica. [PDF]

PLoS ONE, 2010
Autoantibodies that target the water channel aquaporin-4 (AQP4) in neuromyelitis optica (NMO) are IgG1, a T cell-dependent Ig subclass. However, a role for AQP4-specific T cells in this CNS inflammatory disease is not known.
Patricia A Nelson, Mojgan Khodadoust, Thomas Prodhomme, Collin Spencer, Juan Carlos Patarroyo, Michel Varrin-Doyer, Joseph D Ho, Robert M Stroud, Scott S Zamvil   +8 more
doaj   +1 more source

Müller Glia-Vasculature Interactions in the Developing Retina. [PDF]

Glia
Retinal vascular layers form normally despite loss of cholinergic retinal waves. Müller glial processes contact endothelial tip cells early and form Aquaporin‐4‐enriched endfeet. Glial endfoot calcium signals are compartmentalized and occur largely independently of neural activity. ABSTRACT Coordinated signaling among neurons, glia, and the vasculature
Monshietehadi S, Garcia AJ, Smith BE, Tarchick M, Abhayaratne K, Conley A, Feller MB.   +6 more
europepmc   +2 more sources

Neurological scores and Nissl’s staining cell counting of AQP4^+/+ and AQP4^−/− mice.

, 2013
(A) RhVEGF165 alleviated neurological deficits due to ICH of AQP4+/+ and AQP4−/− mice at 1 d, 3 d, and 7 d after injected intracerebroventricularly (n = 6 ...
Yuping Tang (249674), Qiang Dong (380835), Heling Chu (425189)   +2 more
core   +1 more source

Aquaporin-4 protein expression in normal canine brains

BMC Veterinary Research, 2021
Background Aquaporin-4 (AQP4) is in growing recognition as potential marker for cancer progression, differentiation and therapeutic intervention. No information is available about AQP4 expression in the normal canine brain.
Patricia Álvarez, Ester Blasco, Martí Pumarola, Annette Wessmann   +3 more
doaj   +1 more source

Overlapping AQP4 peptides.

, 2013
Overlapping AQP4 peptides.
Bernhard Hemmer (233893), Sudhakar Reddy Kalluri (357524), Marco Prinz (69460), Thomas Korn (220026), Rajneesh Srivastava (143651), Ori Staszewski (357526), Franziska Petermann (220017), Veit Rothhammer (357525)   +7 more
core   +1 more source

Reactivity to AQP4 epitopes in relapsing–remitting multiple sclerosis [PDF]

Journal of Neuroimmunology, 2013
Autoantibodies against the water channel AQP4, expressed predominately in central nervous system astrocytes, are markers and pathogenic factors in Devic's disease. In this study we examined whether Multiple Sclerosis (MS) patients recognize antigenic epitopes on AQP4 that may define distinct disease subsets.
Alexopoulos, H., Kampylafka, E. I., Chatzi, I., Travasarou, M., Karageorgiou, K. E., Dalakas, M. C., Tzioufas, A. G.   +6 more
openaire   +4 more sources