Results 101 to 110 of about 7,154 (227)

ChatGPT Answers the 110-Question Laboratory Enzymology Student Exam: Pass or Fail? [PDF]

Cureus
Hasanefendic B, Pasic A, Duskan S, Sehercehajic E, Jazic Durmisevic A.   +4 more
europepmc   +1 more source

Nurr1 Orchestrates Claustrum Development and Functionality

Advanced Science, Volume 13, Issue 13, 3 March 2026.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan, Andrew G. Newman, Pauline Lange, Susanne Müller, Marco Foddis, Stefan Paul Koch, Philipp Böhm‐Sturm, Maron Mantwill, Carsten Finke, Penghui Deng, Melissa Long, Dietmar Schmitz, Victor Tarabykin   +12 more
wiley   +1 more source

A primer on tRNAs, tRNA-m¹A58 modification, and tRNA derivatives in T-cell activation. [PDF]

Front Cell Dev Biol
Zhao C, Shen J.
europepmc   +1 more source

Development of Peptide Nucleic Acid Based Artificial Ribonucleases, PNAzymes

, 2010
Since mRNA plays such a vital role in the transfer of genetic code from DNA to proteins, approaches involving interference with mRNA are of great interest for use in therapeutics. Amongst these, peptide nucleic acid based nuclease systems (PNAzymes) are being developed for in vivo gene silencing in future.
openaire   +1 more source

Fermented Lacticaseibacillus Paracasei Cultures Ameliorate Colitis by Modulating Microbiota‐Derived Tryptophan Metabolism and Macrophage Polarization

Advanced Science, Volume 13, Issue 13, 3 March 2026.
A solid‐state fermented probiotic (PYW) is developed using wheat bran as substrate, containing high viable Lacticaseibacillus paracasei and bioactive metabolites. PYW alleviates intestinal inflammation by gut microbiota composition, enriching indole derivatives, activating aryl hydrocarbon receptor signaling, and regulating macrophage polarization. PYW
Heng Zhang, Jingzhou Sun, Xin Zheng, Huiqing Yang, Aowen Xie, Yuxuan Ding, Yuxia Mei, Jinshan Li, Yuanliang Hu, Min Ren, Yangyang Liu, Yunxiang Liang   +11 more
wiley   +1 more source

De novo design of hypercompact transcript degraders by engineering substrate-specific toxins and Cas6-CBS system. [PDF]

Nat Commun
Chen PR, Qin PP, Wang YN, Liu PF, Zhang XY, Qian T, Ye BC, Yin BC.   +7 more
europepmc   +1 more source

EGR Proteins Mediate Interferon‐Independent Anti‐HSV‐1 Responses Through Viral and Host Targets

Advanced Science, Volume 13, Issue 13, 3 March 2026.
Early antiviral responses are typically mediated by interferons. However, during HSV‐1 infection, host early growth response (Egr) genes, which are not interferon‐stimulated genes, are quickly induced by viral protein ICP0. EGR proteins, in turn, suppress viral lytic infection by activating viral latency‐associated (LAT) and host immune regulatory ...
Shuaishuai Wang, Fujun Hou, Xunuo Jin, Yuhang Xiang, Dongli Pan   +4 more
wiley   +1 more source

Transcriptomics insights into the functional role of tick Ixodes ricinus proteins metalloprotease and antigen p23. [PDF]

PLoS One
Vaz-Rodrigues R, Duru VC, Nijhof AM, de la Fuente J.   +3 more
europepmc   +1 more source

Wireless Bioelectronic Modulation of Membrane Potential in Glioblastoma Using Carbon Nanotube Porins

Advanced Science, Volume 13, Issue 16, 18 March 2026.
A schematic illustrating glioblastoma cell membrane modulation using carbon nanotube porins (CNTPs) and an applied voltage. CNTPs enable ion flux leading to changes in membrane potential. This figure summarizes the concept of bioelectronic control of cell membrane voltage.
Fleur Groualle, David Onion, Julie A. Watts, Graham A. Rance, Aleksandr Noy, Beth Coyle, Frankie J. Rawson   +6 more
wiley   +1 more source

Progress in the study of molecular markers in the prognosis assessment and recurrence patterns of glioblastoma. [PDF]

Cancer Biol Ther
Hu Y, Ge X, Xie Q, Ma R, Tao Q.
europepmc   +1 more source