Results 71 to 80 of about 7,154 (227)

Synthesis of site-specific artificial ribonucleases

, 2009
Seit gezeigt wurde, dass die genetischen Informationen in Form von DNA gespeichert wird, ist das Geheimnis der DNA-Struktur gelöst, der Mechanismus der Gen-Expression und die Rolle der RNA verstanden worden. Das Interesse für die Chemie und die Biologie der Nukleinsäuren ist somit kontinuierlich gewachsen.
openaire   +1 more source

Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1

The FEBS Journal, EarlyView.
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio, Ana Lucia Cuadros Gamboa, Martina Bertocchi, Filippo Chiesa, Francesca Cargnin, Ettore Mosca, Paride Pelucchi, Viviana Tritto, Stefania Corti, Isabella Ceccherini, Paola Riva, Roberta Benfante, Diego Fornasari   +12 more
wiley   +1 more source

ER proteostasis meets mitochondrial function: contact sites as hubs of communication and therapeutic targets

The FEBS Journal, EarlyView.
Proteostasis ensures proper protein folding, modification, and degradation, while its impairment triggers ER stress. Chronic ER stress and maladaptive UPR via the CHOP–ERO1 axis remodel ERMCs, altering calcium signaling and mitochondrial metabolism.
Giorgia Maria Renna, Alessandro Cherubini, Ersilia Varone, Serena Germani, Alice Marrazza, Ester Zito   +5 more
wiley   +1 more source

Rapid Clearance of Tetracapsuloides bryosalmonae Spores by Freshwater Sponge Ephydatia muelleri: Potential Implications for Controlling Proliferative Kidney Disease in Salmonids

Journal of Fish Diseases, EarlyView.
ABSTRACT Host–parasite interactions are influenced by both abiotic and biotic factors. While abiotic drivers, particularly temperature, have received considerable attention in recent years due to global climate change, the role of biotic factors remains comparatively underexplored.
Lauri Saks, Lilian Pukk, Siim Kahar, Magnus Lauringson, Anti Vasemägi   +4 more
wiley   +1 more source

First Report of the Malacosporean Parasite Tetracapsuloides bryosalmonae in the Faroe Islands Reveals Widespread Distribution and High Prevalence in Brown Trout

Journal of Fish Diseases, EarlyView.
ABSTRACT The myxozoan endoparasite Tetracapsuloides bryosalmonae (Tb), the causative agent of proliferative kidney disease (PKD) in salmonids, has predominantly been reported in temperate regions of continental Europe and North America. Here, we present the first record of Tb in the Faroe Islands, extending the known northern distribution of the ...
Magnus Lauringson, Lilian Pukk, Leivur Janus Hansen, Anti Vasemägi   +3 more
wiley   +1 more source

Gut Microbiota‐Derived Extracellular Vesicles in Patients With Obesity Undergoing Gastric Bypass Surgery

Molecular Microbiology, EarlyView.
Extracellular vesicles (EVs) have been suggested to participate in gut microbiota–host communication. While obesity and bariatric surgery have been shown to alter the gut microbiota composition, changes in gut microbiota‐EVs have not been investigated.
Jenni Hekkala, Anna Kaisanlahti, Mysore V. Tejesvi, Jenni Turunen, Nikke Virtanen, Sonja Karikka, Pande Putu Erawijantari, Anatoliy Samoylenko, Genevieve Bart, Seppo Vainio, Leo Lahti, Janne Hukkanen, Terhi Ruuska‐Loewald, Vesa Koivukangas, Justus Reunanen   +14 more
wiley   +1 more source

Plastid Engineering for Photosynthesis‐Driven Synthesis of Hyaluronic Acid in Tobacco

Plant Biotechnology Journal, EarlyView.
ABSTRACT Hyaluronic acid (HA) is a glycosaminoglycan composed of alternating units of N‐acetylglucosamine and glucuronic acid. High moisture retention, viscoelasticity and biocompatibility are unique features that make HA polymers attractive compounds for medical applications and aesthetic purposes.
Amanda Lopes, Omar Sandoval‐Ibáñez, Stéphanie Arrivault, David Rolo, F. Vanessa Loiacono, Alexander Erban, Daniel Karcher, Stephan Obst, Stephanie Ruf, Joachim Kopka, Ralph Bock   +10 more
wiley   +1 more source

Genetic Mapping and Functional Characterisation of GhCUP Regulating Leaf Curling in Cotton

Plant Biotechnology Journal, EarlyView.
ABSTRACT Leaf size and shape are crucial traits affecting photosynthesis. Moderate leaf curling is believed to be beneficial to photosynthesis because upright leaves are ideal for building a canopy structure with reduced shaded areas to improve light penetration and ventilation.
Haonan Shi, Yanqing Qiao, Xiaohu Ma, Qian‐Hao Zhu, Haohong Tang, Yanlong Jin, Xuefeng Wang, Feng Liu, Jie Sun, Fei Xue   +9 more
wiley   +1 more source

Serial Spatial Transcriptomes Reveal Regulatory Transitions in Maize Leaf Development

Plant Biotechnology Journal, EarlyView.
ABSTRACT Plant leaves originate from the shoot apical meristem (SAM) and undergo a developmental process of highly coordinated gene expression regulation. To date, only a few key regulators have been identified and characterised, so the gene expression cascades responsible for leaf cell specification and differentiation from SAM remain largely elusive.
Chi‐Chih Wu, Ludvig Larsson, Kun‐Ting Hsieh, Chun‐Ping Yu, Yi‐Hua Chen, Kai‐Hsuan Ding, Ho‐Chun Yang, Joakim Lundeberg, Chin‐Min Kimmy Ho, Shu‐Hsing Wu, Mei‐Yeh Jade Lu, Wen‐Hsiung Li   +11 more
wiley   +1 more source

Transcription Profiling of Potato Leaves in Response to Heat Stress at Single‐Cell Resolution

Plant Biotechnology Journal, EarlyView.
ABSTRACT Potato (Solanum tuberosum L.) is a globally important food crop with considerable nutritional and economic value. Heat stress significantly inhibits potato plant growth and tuber development, constraining the sustainable development of the potato industry. Currently, studies on the cellular‐level mechanisms underlying heat adaptation in potato
Shiqi Wen, Ke Wang, Wenqian Liang, Rongrong Liu, Zihan Li, Xinlong Chen, Yan Li, Dianqiu Lv, Hongju Jian   +8 more
wiley   +1 more source