Results 71 to 80 of about 1,485,663 (260)
Mechanism of ribonuclease cytotoxicity
, 1995 Bovine seminal ribonuclease (BS-RNase), a dimeric homolog of bovine pancreatic ribonuclease A (RNase A), is toxic to mammalian cells. In contrast to dimeric BS-RNase, monomeric BS-RNase and RNase A are not cytotoxic and are bound tightly by cytosolic ...
Kim, Jin-Soo +3 more
core +1 more source
Advanced Science, EarlyView.Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen +11 more
wiley +1 more source
Structure and evolution of pancreatic ribonuclease [PDF]
, 1979 Dit proefschrift gaat over de structuur en de evolutie van het spijsverteringsenzym ribonuclease. In het eerste hoofdstuk wordt in het kort de stand van zaken beschreven in de eiwitchemie, waarvoor ribonuclease aI drie decennia dienst doet aIs ...
Lenstra, Johannes Arjen
core +7 more sources
Advanced Science, EarlyView.Helicobacter pylori infection induces sustained upregulation of the RNA‐binding protein IGF2BP1 in gastric epithelial cells, establishing a persistent epitranscriptomic program. IGF2BP1 stabilizes SLC7A11 mRNA in an m6A‐dependent manner to suppress ferroptosis and promote epithelial survival under oxidative stress. Pharmacological inhibition of IGF2BP1
Jing Ning +20 more
wiley +1 more source
Artificial Chemistries - A Review
, 2005 Artificial Chemistries - A Review "What has been left open, however, by the theory of evolution are questions relating to the origin of evolutionary units: How come the prerequisites into being, i.e. the entities that are varied and selected?
Peter Dittrich +2 more
core
Learning models of sequential decision-making with partial specification of agent behavior
, 2019 Artificial agents that interact with other (human or artificial) agents require models in order to reason about those other agents’ behavior. In addition to the predictive utility of these models, maintaining a model that is aligned with an agent’s true ...
Shah, Julie A. +3 more
core +1 more source
Interim Report and Third Quarter Recommendations, October 2020 [PDF]
, 2020 A report containing the National Security Commission on Artificial Intelligence (NSCAI)'s third quarterly memo and second interim report with 66 recommendations in key areas.
National Security Commission on Artificial Intelligence (U.S.)
core
SAV1 in Cooperation With FKBP52 Participates in Implantation
Advanced Science, EarlyView.The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao +10 more
wiley +1 more source
Injection Molding at the MIT Artificial Intelligence Lab [PDF]
, 1995 This paper describes the injection molding equipment at the MIT Artificial Intelligence Lab and how to use it. Topic covered include mold design, insert molding, safety, and material properties.MIT Artificial Intelligence ...
Binnard, Michael
core
National Security Commission on Artificial Intelligence: First Quarter Recommendations, March 2020 [PDF]
, 2020 A quarterly report detailing recommendations for areas identified in most need of attention, ripe for action, or foundational to AI and national security.
National Security Commission on Artificial Intelligence (U.S.)
core