Results 101 to 110 of about 2,544 (153)

Nucleolin-targeting liposomes guided by aptamer AS1411 for the delivery of siRNA for the treatment of malignant melanomas

, 2014
BRAF gene mutation is found in more than 60% of malignant melanomas, which are difficult to treat. In this study, a new tumor-targeting liposome was developed to deliver anti-BRAF siRNA (siBraf) for the treatment of melanomas.
Guo, Yujia, Zhang, Lihe, Wu, Yun, Yang, Zhenjun, Hou, Jianjun, Li, Liyu, Liu, Xinjie   +6 more
core   +1 more source

Erratum: Preparation of AS1411 Aptamer Modified Mn-MoS₂ QDs for Targeted MR Imaging and Fluorescence Labelling of Renal Cell Carcinoma [Corrigendum]. [PDF]

Int J Nanomedicine, 2023
europepmc   +1 more source

Iron(II) phthalocyanine Loaded and AS1411 Aptamer Targeting Nanoparticles: A Nanocomplex for Dual Modal Imaging and Photothermal Therapy of Breast Cancer. [PDF]

Int J Nanomedicine, 2020
He Y, Wang M, Fu M, Yuan X, Luo Y, Qiao B, Cao J, Wang Z, Hao L, Yuan G.   +9 more
europepmc   +1 more source

Simple PEG Modification of DNA Aptamer Based on Copper Ion Coordination for Tumor Targeting. [PDF]

, 2011
A simple modification of a DNA aptamer with poly(ethylene glycol) (PEG) based on metal coordination was developed. N, N-bis(carboxymethyl)-L-lysine (NTA) of a metal chelate residue was chemically introduced to one terminus of PEG. The NTA-introduced PEG (
Jo, Jun-Ichiro, Takafuji, Yoshimasa, Tabata, Yasuhiko   +2 more
core  

Robust aptamer–polydopamine-functionalized M-PLGA–TPGS nanoparticles for targeted delivery of docetaxel and enhanced cervical cancer therapy

International Journal of Nanomedicine, 2016
Guojun Xu,1–3,* Xinghua Yu,2,* Jinxie Zhang,1,2,* Yingchao Sheng,4 Gan Liu,2 Wei Tao,1,2 Lin Mei1,2 1School of Life Sciences, Tsinghua University, Beijing, 2Graduate School at Shenzhen, Tsinghua University, Shenzhen, 3School of Materials Science ...
Xu GJ, Yu XH, Zhang JX, Sheng YC, Liu G, Tao W, Mei L   +6 more
doaj  

Novel Anticancer Triple Formula Based on Aptamer-Conjugated PEGylated Nanoliposomes

Technology in Cancer Research & Treatment
Background Cancer remains a leading cause of death worldwide, necessitating the development of affordable and innovative therapies to reduce its human and economic burden.
Ali Al-Samydai PhD, Hamdi Nsairat PhD, Moath Alqaraleh PhD, Maha N. Abu Hajleh PhD, Areej Jaber PhD, Lidia Al-Halaseh PhD, Hanan Azzam MS, Qasim Khalid Alazzawi PhD, Israa Al-Ani PhD, Simone Carradori PhD, Walhan Alshaer PhD   +10 more
doaj   +1 more source

Development of AS1411 aptamer-conjugated chitosan-carbon dot nanocarriers for targeted drug delivery and fluorescent imaging in breast cancer therapy. [PDF]

J Biol Eng
Mantashlou MJ, Alizadeh E, Moghaddam SV, Afshari NS, Noorbakhsh A.   +4 more
europepmc   +1 more source

Simultaneous targeted delivery of doxorubicin and KRAS suppression by a hybrid molecule containing miR-143 and AS1411 aptamer. [PDF]

Sci Rep
Laowichuwakonnukul K, Soontornworajit B, Arunpanichlert J, Rotkrua P.   +3 more
europepmc   +1 more source

Preparation of AS1411 Aptamer Modified Mn-MoS₂ QDs for Targeted MR Imaging and Fluorescence Labelling of Renal Cell Carcinoma. [PDF]

Int J Nanomedicine, 2019
Zheng S, Zhang M, Bai H, He M, Dong L, Cai L, Zhao M, Wang Q, Xu K, Li J.   +9 more
europepmc   +1 more source

Selective Delivery of an Anticancer Drug with Aptamer-functionalized Liposomes to Breast Cancer Cells in vitro and in vivo

Selective targeting of cancer cells is a critical step in cancer diagnosis and therapy. To address this need, DNA aptamers have attracted significant attention as possible targeting ligands. However, while their use in targeting cancer cells in vitro has
Tang, Li, Yang, Xujuan, Yin, Qian, Dobrucki, Lawrence W., Katzenellenbogen, John A., Helferich, William G., Cheng, Jianjun, Wong, Ngo Yin, Yasui, Norio, Lu, Yi, Wang, Wendan, Hwang, Kevin, Xing, Hang   +12 more
core   +1 more source