Results 11 to 20 of about 101,970 (257)

Characterization of Three L-Asparaginases from Maritime Pine (Pinus pinaster Ait.)

Frontiers in Plant Science, 2017
Asparaginases (ASPG, EC 3.5.1.1) catalyze the hydrolysis of the amide group of L-asparagine producing L-aspartate and ammonium. Three ASPG, PpASPG1, PpASPG2, and PpASPG3, have been identified in the transcriptome of maritime pine (Pinus pinaster Ait ...
Sonia H. Van Kerckhoven, Fernando N. de la Torre, Rafael A. Cañas, Concepción Avila, Francisco R. Cantón, Francisco M. Cánovas   +5 more
doaj   +1 more source

Targeting the Proline–Glutamine–Asparagine–Arginine Metabolic Axis in Amino Acid Starvation Cancer Therapy

Pharmaceuticals, 2021
Proline, glutamine, asparagine, and arginine are conditionally non-essential amino acids that can be produced in our body. However, they are essential for the growth of highly proliferative cells such as cancers.
Macus Tien Kuo, Helen H. W. Chen, Lynn G. Feun, Niramol Savaraj   +3 more
doaj   +1 more source

Asparagine Deprivation Causes a Reversible Inhibition of Human Cytomegalovirus Acute Virus Replication

mBio, 2019
As obligate intracellular pathogens, viruses rely on the host cell machinery to replicate efficiently, with the host metabolism extensively manipulated for this purpose.
Chen-Hsuin Lee, Samantha Griffiths, Paul Digard, Nhan Pham, Manfred Auer, Juergen Haas, Finn Grey   +6 more
doaj   +1 more source

Reducing the Risk of Acrylamide and Other Processing Contaminant Formation in Wheat Products

Foods, 2023
Wheat is a staple crop, consumed worldwide as a major source of starch and protein. Global intake of wheat has increased in recent years, and overall, wheat is considered to be a healthy food, particularly when products are made from whole grains ...
Navneet Kaur, Nigel G. Halford
doaj   +1 more source

Synthesis and Activation of Asparagine in Asparagine Auxotrophs of Saccharomyces cerevisiae [PDF]

European Journal of Biochemistry, 1979
l‐Asparagine synthesis in Saccharomyces cerevisiae is performed by a glutamine‐dependent asparagine synthetase of the type found in higher organisms.Auxotrophy for asparagine has been obtained in two classes of mutants. In class I, asparagine synthetase activity is cancelled. These mutants combinetwo mutations, asnA− and asnB−. Neither asnA− nor asnB−
Ramos, Fernando, Wiame, Jean-Marie
openaire   +3 more sources

Plasma Amino Acids in Horses Suffering from Pituitary Pars Intermedia Dysfunction

Animals, 2022
Pituitary pars intermedia dysfunction is one of the most common diseases of aged horses and ponies. In Parkinson’s disease, which is, similar to PPID, a disease that involves oxidative damage to dopaminergic pathways but with different clinical signs ...
Sabita Diana Stoeckle, Detlef Timmermann, Roswitha Merle, Heidrun Gehlen   +3 more
doaj   +1 more source

Impact of Nitrogen and Sulfur Supply on the Potential of Acrylamide Formation in Organically and Conventionally Grown Winter Wheat

Agronomy, 2018
In a two-year field trial, the effect of nitrogen (N) and sulfur (S) fertilization was investigated on grain yield, grain quality parameters, formation of acrylamide (AA), and the precursor free asparagine (Asn) in organically and conventionally produced
Falko Stockmann, Ernst Albrecht Weber, Pat Schreiter, Nikolaus Merkt, Wilhelm Claupein, Simone Graeff-Hönninger   +5 more
doaj   +1 more source

A Critical Role of Glutamine and Asparagine γ-Nitrogen in Nucleotide Biosynthesis in Cancer Cells Hijacked by an Oncogenic Virus

mBio, 2017
While glutamine is a nonessential amino acid that can be synthesized from glucose, some cancer cells primarily depend on glutamine for their growth, proliferation, and survival.
Ying Zhu, Tingting Li, Suzane Ramos da Silva, Jae-Jin Lee, Chun Lu, Hyungjin Eoh, Jae U. Jung, Shou-Jiang Gao   +7 more
doaj   +1 more source

Strecker degradation products of aspartic and glutamic acids and their amides

Czech Journal of Food Sciences, 2001
Aspartic and glutamic acids, asparagine and glutamine were oxidised with either potassium peroxodisulphate or glyoxal. Nonvolatile products were derivatised and analysed by GC/FID and GC/MS.
J. Rössner, J. Velíšek, F. Pudil, J. Davídek   +3 more
doaj   +1 more source

Different Amino Acids Inhibit or Promote Rhizome Proliferation and Differentiation in Cymbidium goeringii

HortScience, 2020
The proliferation and differentiation of rhizomes are crucial for the propagation of Cymbidium species. We systematically assessed the effects of different concentrations of 20 amino acids on the proliferation and differentiation of C. goeringii rhizomes.
Weiting Huang, Zhongming Fang
doaj   +1 more source