Results 21 to 30 of about 101,970 (257)
This review article gives a survey of principal pathways that lead to the biosynthesis of the proteinogenic amino acids of the glutamic acid group (glutamic acid, glutamine, proline, arginine) and aspartic acid group (aspartic acid, asparagine, threonine,
Jan Velíšek, Karel Cejpek
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Amino Acid Oncometabolism and Immunomodulation of the Tumor Microenvironment in Lung Cancer
The observation that cancer acquires significant changes in its metabolism dates back nearly a century, to Otto Warburg noting that cancer cells preferentially utilize glycolysis even when there are no hypoxic conditions in the growth media.
Johannes F. Fahrmann +2 more
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Nitrogen uptake and free amino acid accumulation was evaluated in two South American cultivars of Lotus corniculatus L. differing in their tolerance to Al stress.
Palove-Balang Peter +2 more
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Asparagine Synthetase Chemotherapy [PDF]
Modern clinical treatments of childhood acute lymphoblastic leukemia (ALL) employ enzyme-based methods for depletion of blood asparagine in combination with standard chemotherapeutic agents. Significant side effects can arise in these protocols and, in many cases, patients develop drug-resistant forms of the disease that may be correlated with up ...
Nigel G J, Richards, Michael S, Kilberg
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Chronoregulation by Asparagine Deamidation [PDF]
Every asparagine in every protein undergoes nonenzymatic deamidation to aspartate or isoaspartate at a rate determined by the surrounding protein structure and cellular environment. Under physiologic conditions, the deamidation half-life of individual asparagines in proteins is proposed to range from less than a day to several centuries.
Weintraub, Steven J. +1 more
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Targeting NAT10 inhibits osteosarcoma progression via ATF4/ASNS-mediated asparagine biosynthesis
Summary: Despite advances in treatment, the prognosis of patients with osteosarcoma remains unsatisfactory, and searching for potential targets is imperative.
Yutong Zou +11 more
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QUANTUM-CHEMICAL SIMULATION OF THE INTERACTION OF AMINO ACIDS WITH CALCIUM CARBONATE
This article presents the results of quantum chemical modeling of the interaction of the CO32-anion with a number of proteinogenic amino acids to identify the most energetically advantageous system and further compare with the results of a laboratory ...
D. M. Remizov +4 more
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Asparagine Synthesis in Pea Leaves, and the Occurrence of an Asparagine Synthetase Inhibitor [PDF]
Asparagine is present in the mature leaves of young pea (Pisum sativum cv Little Marvel) seedlings, and is synthesized in detached shoots. This accumulation and synthesis is greatly enhanced by darkening. In detached control shoots, [(14)C]aspartate was metabolized predominantly to organic acids and, as other workers have shown, there was little ...
K W, Joy, R J, Ireland, P J, Lea
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Asparagine and reducing sugars are the principal precursors of acrylamide in foods. Their main sources in pastries are flour and hen egg yolks. One method of reducing acrylamide content in food may be to add a chickpea protein preparation. The aim of the
Karolina Miśkiewicz +2 more
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Hordeum maritimum With. is a wild salt tolerant cereal present in the saline depressions of the Eastern Tunisia, where it significantly contributes to the annual biomass production.
Emilia Dell’Aversana +7 more
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