Synthesis and Activation of Asparagine in Asparagine Auxotrophs of Saccharomyces cerevisiae [PDF]
European Journal of Biochemistry, 1979 l‐Asparagine synthesis in Saccharomyces cerevisiae is performed by a glutamine‐dependent asparagine synthetase of the type found in higher organisms.Auxotrophy for asparagine has been obtained in two classes of mutants. In class I, asparagine synthetase activity is cancelled. These mutants combinetwo mutations, asnA− and asnB−. Neither asnA− nor asnB−
Ramos, Fernando, Wiame, Jean-Marie
openaire +3 more sources
mBio, 2019 As obligate intracellular pathogens, viruses rely on the host cell machinery to replicate efficiently, with the host metabolism extensively manipulated for this purpose.
Chen-Hsuin Lee +6 more
doaj +1 more source
Reducing the Risk of Acrylamide and Other Processing Contaminant Formation in Wheat Products
Foods, 2023 Wheat is a staple crop, consumed worldwide as a major source of starch and protein. Global intake of wheat has increased in recent years, and overall, wheat is considered to be a healthy food, particularly when products are made from whole grains ...
Navneet Kaur, Nigel G. Halford
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Genetic and Agronomic Control of Free Asparagine Accumulation in Wheat (Triticum aestivum) [PDF]
, 2023 Acrylamide is a processing contaminant found in many different foods. It is formed from free (soluble, non-protein) asparagine and reducing sugars during the Maillard reaction, which occurs during low-moisture, high-temperature processing. In wheat-based
Oddy, J.
core
Plasma Amino Acids in Horses Suffering from Pituitary Pars Intermedia Dysfunction
Animals, 2022 Pituitary pars intermedia dysfunction is one of the most common diseases of aged horses and ponies. In Parkinson’s disease, which is, similar to PPID, a disease that involves oxidative damage to dopaminergic pathways but with different clinical signs ...
Sabita Diana Stoeckle +3 more
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Asparagine bioavailability governs metastasis in a model of breast cancer
Nature, 2018 Using a functional model of breast cancer heterogeneity, we previously showed that clonal sub-populations proficient at generating circulating tumour cells were not all equally capable of forming metastases at secondary sites.
S. Knott +20 more
semanticscholar +1 more source
Construction of a network describing asparagine metabolism in plants and its application to the identification of genes affecting asparagine metabolism in wheat under drought and nutritional stress [PDF]
, 2018 A detailed network describing asparagine metabolism in plants was constructed using published data from Arabidopsis (Arabidopsis thaliana) maize (Zea mays), wheat (Triticum aestivum), pea (Pisum sativum), soybean (Glycine max), lupin (Lupus albus) and ...
Bo, V +11 more
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Agronomy, 2018 In a two-year field trial, the effect of nitrogen (N) and sulfur (S) fertilization was investigated on grain yield, grain quality parameters, formation of acrylamide (AA), and the precursor free asparagine (Asn) in organically and conventionally produced
Falko Stockmann +5 more
doaj +1 more source
MAPK signaling regulates c‐MYC for melanoma cell adaptation to asparagine restriction
EMBO Reports, 2021 Amino acid restriction is among promising potential cancer treatment strategies. However, cancer cells employ a multitude of mechanisms to mount resistance to amino acid restriction, which impede the latter’s clinical development.
G. Pathria +4 more
semanticscholar +1 more source
Strecker degradation products of aspartic and glutamic acids and their amides
Czech Journal of Food Sciences, 2001 Aspartic and glutamic acids, asparagine and glutamine were oxidised with either potassium peroxodisulphate or glyoxal. Nonvolatile products were derivatised and analysed by GC/FID and GC/MS.
J. Rössner +3 more
doaj +1 more source