Results 31 to 40 of about 2,749,588 (276)
Anaesthetic phencyclidine, blocker of the ATP‐sensitive potassium channels [PDF]
FEBS Letters, 1994 The double sucrose gap and patch‐clamp studies revealed that phencyclidine blocked the ATP‐sensitive K+ channel in isolated cardiac cells (half‐maximal inhibition at ≈20 μM; Hill coefficient ≈1). 10μM phencyclidine increased the inward Ca2+ current and blocked the outward K+ current in the frog auricle trabeculae.
Kokoz, Yuri M. +4 more
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Intractable hyperkalemia due to nicorandil induced potassium channel syndrome
Annals of Cardiac Anaesthesia, 2015 Nicorandil is a commonly used antianginal agent, which has both nitrate-like and ATP-sensitive potassium (K ATP ) channel activator properties. Activation of potassium channels by nicorandil causes expulsion of potassium ions into the extracellular space
Vivek Chowdhry, B B Mohanty
doaj +1 more source
Structure and function of potassium and calcium channels [PDF]
, 2005 In this thesis, potassium channels human Kv2.1 and rat Kv2.1, along with calcium channels Ca, 1.2, Ca, 3.1, and chimeras have been studied. These channels were expressed in Xenopuso ocytesf or electrophysiological experiments using two electrode voltage
Stevens, Louisa Rebecca
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Nicorandil-Induced Hyperkalemia in a Uremic Patient
Case Reports in Medicine, 2012 Nicorandil is an antianginal agent with nitrate-like and ATP-sensitive potassium channel activator properties. After activation of potassium channels, potassium ions are expelled out of the cells, which lead to membrane hyperpolarization, closure of ...
Hung-Hao Lee +4 more
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Expression of ATP-sensitive potassium channels in human pregnant myometrium
Reproductive Biology and Endocrinology, 2011 Background Potassium channels play critical roles in the regulation of cell membrane potential, which is central to the excitability of myometrium. The ATP-sensitive potassium (KATP) channel is one of the most abundant potassium channels in myometrium ...
Hui Ning +7 more
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Frontiers in Nutrition, 2023 BackgroundMigraine is a prevalent neurovascular headache disorder. The link between dietary potassium and blood pressure has been established. We sought to delineate the relationship between dietary potassium intake and the prevalence of migraines ...
Lisi Xu +5 more
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Do KATP channels open as a prominent and early feature during ischaemia in the Langendorff-perfused rat heart? [PDF]
, 2000 The objective was to investigate whether myocardial adenosine triphosphate-sensitive K<sup>+</sup> (K<sub>ATP</sub>) channels open during the first 10 min of regional ischaemia in Langendorff-perfused rat hearts.
Northover, B.J. +2 more
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Multidimensional Regulation of Cardiac Mitochondrial Potassium Channels
Cells, 2021 Mitochondria play a fundamental role in the energetics of cardiac cells. Moreover, mitochondria are involved in cardiac ischemia/reperfusion injury by opening the mitochondrial permeability transition pore which is the major cause of cell death.
Bogusz Kulawiak +2 more
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ATP-Sensitive Potassium Channels in the Cerebral Circulation [PDF]
Stroke, 2003 Background— In brain blood vessels, electrophysiological studies proving the existence of ATP-sensitive potassium channels (K ATP ) are scarce. However, numerous pharmacological studies establish the importance of K ATP channels in these blood vessels ...
openaire +2 more sources
A KATP channel opener inhibited myocardial reperfusion action potential shortening and arrhythmias [PDF]
, 2001 Low concentrations of certain K<sub>ATP</sub> channel openers have been reported to exert a moderate inhibitory effect on arrhythmias during post-ischaemic early myocardial reperfusion, but the accompanying effects on the time course of ...
Northover, B.J. +5 more
core +1 more source