Results 31 to 40 of about 45,380 (194)
BackgroundMigraine is a prevalent neurovascular headache disorder. The link between dietary potassium and blood pressure has been established. We sought to delineate the relationship between dietary potassium intake and the prevalence of migraines ...
Lisi Xu +5 more
doaj +1 more source
Nicorandil-Induced Hyperkalemia in a Uremic Patient
Nicorandil is an antianginal agent with nitrate-like and ATP-sensitive potassium channel activator properties. After activation of potassium channels, potassium ions are expelled out of the cells, which lead to membrane hyperpolarization, closure of ...
Hung-Hao Lee +4 more
doaj +1 more source
Expression of ATP-sensitive potassium channels in human pregnant myometrium
Background Potassium channels play critical roles in the regulation of cell membrane potential, which is central to the excitability of myometrium. The ATP-sensitive potassium (KATP) channel is one of the most abundant potassium channels in myometrium ...
Hui Ning +7 more
doaj +1 more source
Multidimensional Regulation of Cardiac Mitochondrial Potassium Channels
Mitochondria play a fundamental role in the energetics of cardiac cells. Moreover, mitochondria are involved in cardiac ischemia/reperfusion injury by opening the mitochondrial permeability transition pore which is the major cause of cell death.
Bogusz Kulawiak +2 more
doaj +1 more source
Identification of putative potassium channel homologues in pathogenic protozoa [PDF]
K(+) channels play a vital homeostatic role in cells and abnormal activity of these channels can dramatically alter cell function and survival, suggesting that they might be attractive drug targets in pathogenic organisms.
Prole, D L +3 more
core +1 more source
ATP-Sensitive Potassium Channels in the Cerebral Circulation [PDF]
Background— In brain blood vessels, electrophysiological studies proving the existence of ATP-sensitive potassium channels (K ATP ) are scarce. However, numerous pharmacological studies establish the importance of K ATP channels in these blood vessels ...
openaire +2 more sources
Ion Channel Dysfunction in Astrocytes in Neurodegenerative Diseases
Astrocytes play an important role in the central nervous system (CNS). Ion channels in these cells not only function in ion transport, and maintain water/ion metabolism homeostasis, but also participate in physiological processes of neurons and glial ...
Sijian Wang +5 more
doaj +1 more source
Anionic Phospholipids Activate ATP-sensitive Potassium Channels [PDF]
The ATP-sensitive potassium channel (KATP) controls insulin release in pancreatic beta-cells and also modulates important functions in other cell types. In this study we report that anionic phospholipids activated KATP in pancreatic beta-cells, cardiac myocytes, skeletal muscle cells, and a cloned KATP composed of two subunits (SUR/Kir6.
Z, Fan, J C, Makielski
openaire +2 more sources
The selectivity, voltage-dependence and acid sensitivity of the tandem pore potassium channel TASK-1 : contributions of the pore domains [PDF]
We have investigated the contribution to ionic selectivity of residues in the selectivity filter and pore helices of the P1 and P2 domains in the acid sensitive potassium channel TASK-1.
Sutcliffe, M. J. +14 more
core +1 more source
Membrane trafficking of ATP-sensitive potassium channels [PDF]
ATP-sensitive potassium (KATp) channels are known to play a vital role in the regulation of insulin secretion from pancreatic 0-cells. Changes in the ratio of [ATP]/[ADP] within the cell are known to regulate the activity of channels, but very little is ...
Smith, Andrew James
core

