Results 51 to 60 of about 77,404 (202)

Autophagy Induced by Simian Retrovirus Infection Controls Viral Replication and Apoptosis of Jurkat T Lymphocytes

open access: yesViruses, 2020
Autophagy and apoptosis are two important evolutionarily conserved host defense mechanisms against viral invasion and pathogenesis. However, the association between the two pathways during the viral infection of T lymphocytes remains to be elucidated ...
Jingting Zhu   +5 more
doaj   +1 more source

The intricate dance: host autophagy and Coxiella burnetii infection

open access: yesFrontiers in Microbiology, 2023
Q fever is a zoonotic disease caused by Coxiella burnetii, an obligatory intracellular bacterial pathogen. Like other intracellular pathogens, C. burnetii is able to survive and reproduce within host cells by manipulating host cellular processes.
Tingting Wang   +3 more
doaj   +1 more source

in initiating autophagosome biogenesis

open access: yes, 2023
Autophagy is a process of regulated degradation. It eliminates damaged and unnecessary cellular components by engulfing them with a de novo‐ generated organelle: the double‐membrane autophagosome.
Anh Nguyen   +3 more
core   +1 more source

The phosphatidylinositol 3-phosphate effector FYVE3 regulates FYVE2-dependent autophagy in Arabidopsis thaliana

open access: yesFrontiers in Plant Science, 2023
Phosphatidylinositol 3-phosphate (PI3P) is a signaling phospholipid that play a key role in endomembrane trafficking, specifically autophagy and endosomal trafficking.
Jeong Hun Kim   +4 more
doaj   +1 more source

COP9 Signalosome Regulates Autophagosome Maturation

open access: yes, 2011
Background— Autophagy is essential to intracellular homeostasis and is involved in the pathophysiology of a variety of diseases. Mechanisms regulating selective autophagy remain poorly understood.
Faqian Li   +4 more
core   +1 more source

The Intertwined Life Cycles of Enterovirus and Autophagy

open access: yesVirulence, 2019
Enteroviruses (EVs) are the most common human pathogens worldwide. Recent international outbreaks in North America and South East Asia have emphasized the need for more effective anti-viral therapies.
Yasir Mohamud, Honglin Luo
doaj   +1 more source

Assays to Monitor Autophagy in Saccharomyces cerevisiae

open access: yesCells, 2017
Autophagy is an intracellular process responsible for the degradation and recycling of cytoplasmic components. It selectively removes harmful cellular material and enables the cell to survive starvation by mobilizing nutrients via the bulk degradation of
Raffaela Torggler   +2 more
doaj   +1 more source

Conserved regulation of autophagosome-lysosome fusion through YKT6 phosphorylation

open access: yesAutophagy Reports, 2023
YKT6 is a SNARE (Soluble N-ethylmaleimide-Sensitive Fusion Protein Attachment Protein Receptor) protein governing membrane fusion events of several cellular organelles.
Pablo Sánchez-Martín, Claudine Kraft
doaj   +1 more source

Limited Heme Oxygenase Contribution to Modulating the Severity of Salmonella enterica serovar Typhimurium Infection

open access: yesAntioxidants, 2022
An important virulence trait of Salmonella enterica serovar Typhimurium (S. Typhimurium) is the ability to avoid the host immune response, generating systemic and persistent infections.
Valentina P. Sebastián   +13 more
doaj   +1 more source

Membrane Contact Sites in Autophagy

open access: yesCells, 2022
Eukaryotes utilize different communication strategies to coordinate processes between different cellular compartments either indirectly, through vesicular transport, or directly, via membrane contact sites (MCSs).
Emma Zwilling, Fulvio Reggiori
doaj   +1 more source

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