Results 51 to 60 of about 77,404 (202)
Autophagy and apoptosis are two important evolutionarily conserved host defense mechanisms against viral invasion and pathogenesis. However, the association between the two pathways during the viral infection of T lymphocytes remains to be elucidated ...
Jingting Zhu +5 more
doaj +1 more source
The intricate dance: host autophagy and Coxiella burnetii infection
Q fever is a zoonotic disease caused by Coxiella burnetii, an obligatory intracellular bacterial pathogen. Like other intracellular pathogens, C. burnetii is able to survive and reproduce within host cells by manipulating host cellular processes.
Tingting Wang +3 more
doaj +1 more source
in initiating autophagosome biogenesis
Autophagy is a process of regulated degradation. It eliminates damaged and unnecessary cellular components by engulfing them with a de novo‐ generated organelle: the double‐membrane autophagosome.
Anh Nguyen +3 more
core +1 more source
Phosphatidylinositol 3-phosphate (PI3P) is a signaling phospholipid that play a key role in endomembrane trafficking, specifically autophagy and endosomal trafficking.
Jeong Hun Kim +4 more
doaj +1 more source
COP9 Signalosome Regulates Autophagosome Maturation
Background— Autophagy is essential to intracellular homeostasis and is involved in the pathophysiology of a variety of diseases. Mechanisms regulating selective autophagy remain poorly understood.
Faqian Li +4 more
core +1 more source
The Intertwined Life Cycles of Enterovirus and Autophagy
Enteroviruses (EVs) are the most common human pathogens worldwide. Recent international outbreaks in North America and South East Asia have emphasized the need for more effective anti-viral therapies.
Yasir Mohamud, Honglin Luo
doaj +1 more source
Assays to Monitor Autophagy in Saccharomyces cerevisiae
Autophagy is an intracellular process responsible for the degradation and recycling of cytoplasmic components. It selectively removes harmful cellular material and enables the cell to survive starvation by mobilizing nutrients via the bulk degradation of
Raffaela Torggler +2 more
doaj +1 more source
Conserved regulation of autophagosome-lysosome fusion through YKT6 phosphorylation
YKT6 is a SNARE (Soluble N-ethylmaleimide-Sensitive Fusion Protein Attachment Protein Receptor) protein governing membrane fusion events of several cellular organelles.
Pablo Sánchez-Martín, Claudine Kraft
doaj +1 more source
An important virulence trait of Salmonella enterica serovar Typhimurium (S. Typhimurium) is the ability to avoid the host immune response, generating systemic and persistent infections.
Valentina P. Sebastián +13 more
doaj +1 more source
Membrane Contact Sites in Autophagy
Eukaryotes utilize different communication strategies to coordinate processes between different cellular compartments either indirectly, through vesicular transport, or directly, via membrane contact sites (MCSs).
Emma Zwilling, Fulvio Reggiori
doaj +1 more source

