Results 31 to 40 of about 1,942 (177)
Cold Spring Harbor Perspectives in Biology, 2016 Axonemal dyneins form the inner and outer rows of arms associated with the doublet microtubules of motile cilia. These enzymes convert the chemical energy released from adenosine triphosphate (ATP) hydrolysis into mechanical work by causing the doublets to slide with respect to each other.
openaire +2 more sources
Cryo-EM of dynein microtubule-binding domains shows how an axonemal dynein distorts the microtubule
eLife, 2019 Dyneins are motor proteins responsible for transport in the cytoplasm and the beating of axonemes in cilia and flagella. They bind and release microtubules via a compact microtubule-binding domain (MTBD) at the end of a coiled-coil stalk.
Samuel E Lacey +3 more
doaj +1 more source
Basal body and flagellum mutants reveal a rotational constraint of the central pair microtubules in the axonemes of trypanosomes. [PDF]
, 2006 Productive beating of eukaryotic flagella and cilia requires a strict regulation of axonemal dynein activation. Fundamental to any description of axonemal beating is an understanding of the significance of the central pair microtubules and the degree to ...
Wickstead, B. +8 more
core +1 more source
Trypanin, a component of the flagellar Dynein regulatory complex, is essential in bloodstream form African trypanosomes. [PDF]
PLoS Pathogens, 2006 The Trypanosoma brucei flagellum is a multifunctional organelle with critical roles in motility, cellular morphogenesis, and cell division. Although motility is thought to be important throughout the trypanosome lifecycle, most studies of flagellum ...
Katherine S Ralston, Kent L Hill
doaj +1 more source
Axonemal dyneins and force generation by neurons in Drosophila melanogaster ear [PDF]
, 2013 Analogous to vertebrate hair cells, the mechanosensory cilia of Drosophila auditory neurons are motile and serve dual, transducing and actuating roles.
Karak, Somdatta
core +1 more source
Force-Generating Mechanism of Axonemal Dynein in Solo and Ensemble
, 2020 In eukaryotic cilia and flagella, various types of axonemal dyneins orchestrate their distinct functions to generate oscillatory bending of axonemes.
Kazuhiro Oiwa +2 more
core +1 more source
A liquid-like organelle at the root of motile ciliopathy
eLife, 2018 Motile ciliopathies are characterized by specific defects in cilia beating that result in chronic airway disease, subfertility, ectopic pregnancy, and hydrocephalus.
Ryan L Huizar +7 more
doaj +1 more source
Inner lumen proteins stabilize doublet microtubules in cilia and flagella
Nature Communications, 2019 Microtubules in cilia are sufficiently stable to withstand the beating motion, but how they are stabilized while serving as tracks for intraflagellar transport and axonemal dyneins remains unknown.
Mikito Owa +8 more
doaj +1 more source
, 2012 (A) Dynein network: The green coloring indicates 4 out of 5 hits regarding axonemal dyneins. DNAH7 (also identified in our screen) was not part of the network. Blue symbols represent dyneins which were part of the library but were not determined as hits.
Ursula Holtzmann (180882) +7 more
core +1 more source