Results 41 to 50 of about 15,931 (218)

Microtubular Dysfunction and Male Infertility

open access: yesThe World Journal of Men's Health, 2020
Microtubules are the prime component of the cytoskeleton along with microfilaments. Being vital for organelle transport and cellular divisions during spermatogenesis and sperm motility process, microtubules ascertain functional capacity of sperm. Also,
Sezgin Gunes   +7 more
doaj   +1 more source

TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella

open access: yeseLife, 2014
Cilia/flagella are assembled and maintained by the process of intraflagellar transport (IFT), a highly conserved mechanism involving more than 20 IFT proteins. However, the functions of individual IFT proteins are mostly unclear.
Hiroaki Ishikawa   +11 more
doaj   +1 more source

Life-Saver or Undertaker: The Relationship between Primary Cilia and Cell Death in Vertebrate Embryonic Development

open access: yesJournal of Developmental Biology, 2022
The development of multicellular organisms requires a tightly coordinated network of cellular processes and intercellular signalling. For more than 20 years, it has been known that primary cilia are deeply involved in the mediation of intercellular ...
Thorsten Pfirrmann, Christoph Gerhardt
doaj   +1 more source

Parasite motility is critical for virulence of African trypanosomes. [PDF]

open access: yes, 2018
African trypanosomes, Trypanosoma brucei spp., are lethal pathogens that cause substantial human suffering and limit economic development in some of the world's most impoverished regions.
Geng, Quanjie   +6 more
core   +1 more source

Boarder control on the IFT train

open access: yeseLife, 2014
New details are revealed about the system that transports proteins to the tip of flagella during growth.
Cécile Fort, Philippe Bastin
doaj   +1 more source

IC2 participates in the cooperative activation of outer arm dynein densely attached to microtubules

open access: yesCell Structure and Function, 2023
Ciliary outer-arm dynein (OAD) consists of heavy chains (HCs), intermediate chains (ICs), and light chains (LCs), of which HCs are the motor proteins that produce force.
Yusuke Kondo   +6 more
doaj   +1 more source

Functional modulation of IFT kinesins extends the sensory repertoire of ciliated neurons in Caenorhabditis elegans [PDF]

open access: yes, 2006
The diversity of sensory cilia on Caenorhabditis elegans neurons allows the animal to detect a variety of sensory stimuli. Sensory cilia are assembled by intraflagellar transport (IFT) kinesins, which transport ciliary precursors, bound to IFT particles,
Evans, James E.   +6 more
core   +2 more sources

Second harmonic microscopy of axonemes

open access: yesOptics Express, 2009
We performed Second Harmonic Microscopy of axonemes obtained from sea urchin sperm. Using polarization analysis and a trade-off between signal and photodamage, we were able to determine, for the first time to our knowledge, the nonlinear susceptibility chizxx/chixzx = 1.1+/-0.2 and chizzz/chixzx = 4+/-0.5 of axonemes.
Odin, Christophe   +3 more
openaire   +3 more sources

Modulation of the asymmetry of sea urchin sperm flagellar bending by calmodulin [PDF]

open access: yes, 1985
Sea urchin spermatozoa demembranated with Triton X-100 in the presence of EGTA, termed potentially asymmetric, generate asymmetric bending waves in reactivation solutions containing EGTA. After they are converted to the potentially symmetric condition by
Brokaw, C. J., Nagayama, S. M.
core   +2 more sources

Heat shock induces rapid resorption of primary cilia [PDF]

open access: yes, 2012
Primary cilia are involved in important developmental and disease pathways, such as the regulation of neurogenesis and tumorigenesis. They function as sensory antennae and are essential in the regulation of key extracellular signalling systems.
Anckar   +32 more
core   +1 more source

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