Results 11 to 20 of about 510,395 (260)
CRISPR-Cas9-Based Genome Editing and Cytidine Base Editing in Acinetobacter baumannii
STAR Protocols, 2020 Summary: Infections caused by drug-resistant Acinetobacter baumannii have posed a serious threat to global public health. However, genetic manipulation methods, the primary way to study pathogenesis and drug-resistance mechanisms, remain time consuming ...
Yu Wang, Zhipeng Wang, Quanjiang Ji
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Be-dataHIVE: a base editing database
BMC BioinformaticsBase editing is an enhanced gene editing approach that enables the precise transformation of single nucleotides and has the potential to cure rare diseases.
Lucas Schneider, Peter Minary
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Base editing and prime editing in laboratory animals [PDF]
Laboratory Animals, 2021 Genome editing by programmable RNA-dependent Cas endonucleases has revolutionised the field of genome engineering, achieving targeted genomic change at unprecedented efficiencies with considerable application in laboratory animal research. Despite its ease of use and wide application, there remain concerns about the precision of this technology and a ...
Federico Caso, Benjamin Davies
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Journal of Visual Languages and Sentient Systems, 2017 In introductory programming teaching, block-based editors have become very popular because they offer a number of strong advantages for beginning programmers: They avoid many syntax errors, can display all available instructions for visual selection and encourage experimentation with little requirement for recall. Among proficient programmers, however,
Kölling, Michael +2 more
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CRISPR base editing and prime editing: DSB and template-free editing systems for bacteria and plants
Synthetic and Systems Biotechnology, 2020 CRISPR-Cas (Clustered Regularly Interspaced Short Palindromic Repeats-CRISPR associated) has been extensively exploited as a genetic tool for genome editing.
Abdullah +5 more
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Virus Research, 2023 RNA editing of the hepatitis delta virus (HDV) is essential for generating the large delta antigen, which is crucial for virion assembly. In HDV genotype 1 (HDV-1), editing occurs within the context of the unbranched rod-like structure characteristic of ...
Chao-Wei Hsu +3 more
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Development of a Simple and Quick Method to Assess Base Editing in Human Cells
Molecular Therapy: Nucleic Acids, 2020 Base editing is a form of genome editing that can directly convert a single base (C or A) to another base (T or G), which is of great potential in biomedical applications.
Xiujuan Lv +12 more
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Examination of the Cell Cycle Dependence of Cytosine and Adenine Base Editors
Frontiers in Genome Editing, 2022 Base editors (BEs) are genome editing agents that install point mutations with high efficiency and specificity. Due to their reliance on uracil and inosine DNA damage intermediates (rather than double-strand DNA breaks, or DSBs), it has been hypothesized
Cameron A. Burnett +6 more
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And now, evidence based editing [PDF]
BMJ, 1995 The third congress on peer review will be in Prague in September 1997 Peer review is slow, expensive, prone to bias, corruptible, and possibly anti-innovatory.1 Yet it is central not only to the production of scientific journals but to all of science. Like democracy it may be an imperfect process, but it is better than the alternatives.2 3 4 Or is it?
R, Smith, D, Rennie
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