Results 31 to 40 of about 510,395 (260)
Health research in the era of artificial intelligence: Advances in gene-editing study
Medicine PlusIn recent years, gene editing technology, represented by clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) has made a revolutionary breakthrough.
Mengyao Dai +5 more
doaj +1 more source
Base Editing and Prime Editing
, 2023 AbstractThe development of new adaptations of CRISPR-based genome editing platforms, such as base editing and prime editing, made it possible to broaden the scope and applications of genome editing in plants. First base editing and, more recently, prime editing evade the creation of double-stranded breaks in deoxyribonucleic acid (DNA) and the ...
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Frontiers in Genetics, 2022 Stargardt macular dystrophy (STGD1) is the most common form of inherited childhood blindness worldwide and for which no current treatments exist. It is an autosomal recessive disease caused by mutations in ABCA4.
Elena Piotter +3 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei +17 more
wiley +1 more source
Image-based object editing [PDF]
Fourth International Conference on 3-D Digital Imaging and Modeling, 2003. 3DIM 2003. Proceedings., 2004 We examine the problem of editing complex 3D objects. We convert the problem of editing a 3D object of arbitrary size and surface properties to a problem of editing a 2D image. We allow the user to specify edits in both geometry and surface properties from any view and at any resolution they find convenient, regardless of the interactive rendering ...
Holly E. Rushmeier +4 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Leukemia is the most common childhood cancer in Mexico, and acute lymphoblastic leukemia (ALL) is the most frequent subtype. Exposure to high concentrations of benzene has been associated with ALL incidence, particularly in urban areas. This study evaluated the relationship between distance to benzene emission sources and the number
Orlando Rivera Zurita +5 more
wiley +1 more source
CRISPR/Cas9 nickase-mediated cytosine base editing in Trichoderma koningiopsis
MycologyBase editors are regarded as reliable and precise editing tools due to their ability to efficiently and accurately modify the target genes without inducing double-strand breaks (DSBs).
Yushi Fu +6 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Pediatric bone sarcoma patients and survivors may experience psychosocial challenges related to childhood cancer after their intensive, body‐altering treatment. This cross‐sectional study aimed to evaluate generic and survivor‐specific psychosocial outcomes in a national cohort of pediatric bone sarcoma patients and survivors, and ...
Hinke van der Hoek +14 more
wiley +1 more source
mBio, 2023 Genome-editing (GE) techniques like base editing are ideal for introducing novel gain-of-function mutations and in situ protein evolution. Features of base editors (BEs) such as higher efficacy, relaxed protospacer adjacent motif (PAM), and a broader ...
Rahul Mahadev Shelake +2 more
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Edition Schemes Based on BSE [PDF]
, 2005 Edition is an important and useful task in supervised classification specifically for instance-based classifiers because edition discards from the training set those useless or harmful objects for the classification accuracy and it helps to reduce the size of the original training sample and to increase both the classification speed and accuracy.
José Arturo Olvera-López +2 more
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