Mitochondrial fission is associated with UCP1 activity in human brite/beige adipocytes
Molecular Metabolism, 2018 Objective: Thermogenic adipocytes (i.e. brown or brite/beige adipocytes) are able to burn large amounts of lipids and carbohydrates as a result of highly active mitochondria and enhanced uncoupled respiration, due to UCP1 activity.
Didier F. Pisani +10 more
doaj +2 more sources
Thermogenic Activation Downregulates High Mitophagy Rate in Human Masked and Mature Beige Adipocytes [PDF]
International Journal of Molecular Sciences, 2020 Zoltan Balajthy +2 more
exaly +2 more sources
Effects of exercise on brown and beige adipocytes. [PDF]
Biochim Biophys Acta Mol Cell Biol Lipids, 2019 Physical exercise leads to beneficial effects in numerous tissues and organ systems and offers protection against obesity and type 2 diabetes. Recent studies have investigated the role of exercise on brown adipose tissue (BAT) and white adipose tissue (WAT), and have indicated marked adaptations to each tissue with exercise.
Dewal RS, Stanford KI.
europepmc +3 more sources
Alternative isoform expression of key thermogenic genes in human beige adipocytes [PDF]
Frontiers in EndocrinologyNolwenn Briand +2 more
exaly +2 more sources
Editorial: Novel regulatory mechanisms behind thermogenesis of brown and beige adipocytes, volume II [PDF]
Frontiers in EndocrinologyRini Arianti +2 more
exaly +2 more sources
Unraveling the Interaction Between Beige Adipocytes and the Sympathetic Nervous System [PDF]
, 2021 Obesity affects more than one in three adults in the United States and is a significant risk factor for a constellation of chronic diseases. The crucial role of adipose tissue in energy balance has driven great interest in investigating this tissue as a ...
Chi, Jingyi
core +1 more source
Metabolic programming of a beige adipocyte phenotype by genistein [PDF]
Molecular Nutrition & Food Research, 2016 ScopePromoting the development of brown or beige adipose tissue may protect against obesity and related metabolic features, and potentially underlies protective effects of genistein in mice.Methods and resultsWe observed that application of genistein to 3T3‐L1 adipocytes changed the lipid distribution from large droplets to a multilocular distribution,
Aziz SA +5 more
openaire +3 more sources
A Method to Induce Brown/Beige Adipocyte Differentiation from Murine Preadipocytes
Bio-Protocol, 2021 Adipocytes exhibit different morphological and functional characteristics, depending on their anatomical location, developmental origin, and stimulus. While white adipocytes tend to accumulate energy as triglycerides, brown and beige adipocytes tend to ...
Andréa Rocha +3 more
doaj +1 more source
ESRRG and PERM1 Govern Mitochondrial Conversion in Brite/Beige Adipocyte Formation
Frontiers in Endocrinology, 2020 When exposed to cold temperatures, mice increase their thermogenic capacity by an expansion of brown adipose tissue mass and the formation of brite/beige adipocytes in white adipose tissue depots.
Sebastian Müller +8 more
doaj +1 more source
Genetically prolonged beige fat in male mice confers long-lasting metabolic health
Nature Communications, 2023 A potential therapeutic target to curb obesity and diabetes is thermogenic beige adipocytes. However, beige adipocytes quickly transition into white adipocytes upon removing stimuli.
Ruifan Wu +19 more
doaj +1 more source