Results 61 to 70 of about 6,430 (223)

Evaluation of suitable reference genes for gene expression studies in the developing mouse cortex using RT-qPCR

BMC Neuroscience
Real-time quantitative PCR (RT-qPCR) is a widely used method to investigate gene expression in neuroscience studies. Accurate relative quantification of RT-qPCR requires the selection of reference genes that are stably expressed across the experimental ...
Ananya Uppalapati, Timothy Wang, Lena H. Nguyen   +2 more
semanticscholar   +1 more source

Cross‐Talk Between Histamine H2 Receptor and Glucocorticoid Receptor: Potential Implications in Acute Myeloid Leukemia Treatment

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT This study investigates the impact of histamine H2 receptor activation on glucocorticoid receptor (GR)‐mediated transcriptional activity, as well as its effects on leukemic cell proliferation and chemotherapy resistance. We demonstrate that activation of the histamine H2 receptor by its specific agonist, amthamine, enhances GR transcriptional ...
Valeria Torralba‐Agu, Natalia Fernández, Carina Shayo, Carlos Davio, C. Daniel Zappia, Federico Monczor   +5 more
wiley   +1 more source

Selection and validation of reference genes suitable for gene expression analysis by Reverse Transcription Quantitative real-time PCR in Acinetobacter baumannii

Scientific Reports
Acinetobacter baumannii is a Gram-negative bacterium considered an emerging multi-drug-resistant pathogen. Furthermore, this bacterium can survive in extreme environmental conditions, which makes it a frequent cause of nosocomial infection outbreaks ...
Paloma Cristina Alves de Oliveira, Juliana Baboghlian, Clarissa Orandina Aparecida Ramos, Alquiandra S. F. Mançano, Andréia de Melo Porcari, Raquel Girardello, Lúcio Fábio Caldas Ferraz   +6 more
semanticscholar   +1 more source

Validation of suitable reference genes by various algorithms for gene expression analysis in Isodon rubescens under different abiotic stresses

Scientific Reports, 2022
Isodon rubescens (Hemsley) H. Hara (Lamiaceae) is a traditional Chinese medicine plant that has been used to treat various human diseases. Oridonin is one of the main active ingredients, and the route of its molecular biosynthesis remains to be ...
Conglong Lian, Bao Zhang, Jingfan Yang, Jinxu Lan, Han Yang, Kaihua Guo, Jingjing Li, Sui-Qin Chen   +7 more
semanticscholar   +1 more source

Unveiling the Functional Role of KIF21B in Microglia Inflammatory Response

Glia, Volume 74, Issue 9, September 2026.
Microglia express KIF21B in both sexes. KIF21B binds to microglia cytoskeleton; inflammation alters such interaction promoting a phagocytic state in females. In male microglia KIF21B modulates migration. ABSTRACT Microglia are brain immune cells that maintain homeostasis and respond to injury, changing cell morphology to drive inflammation, migration ...
Danny Ganchala, Alvaro Bautista‐Abad, Daniel Pinto‐Benito, Julia Simon‐Areces, Daniela Grassi, Francesco Paolo Ulloa Severino, Maria‐Angeles Arevalo   +6 more
wiley   +1 more source

Expression stability analysis of the reference genes by BestKeeper.

, 2013
Expression stability analysis of the reference genes by BestKeeper.
Sun-Uk Kim (282187), Kyoung-Min Lee (282191), Kyu-Tae Chang (282192), Ji-Su Kim (282189), Youngjeon Lee (282184), Sang-Hyun Kim (282188), Sang-Je Park (282182), Kyoung-Min Kim (282185), Young-Hyun Kim (282183), Kang-Jin Jeong (282190), Sang-Rae Lee (282186), Heui-Soo Kim (18101), Jae-Won Huh (18098)   +12 more
core   +2 more sources

Selection and Validation of Reliable Reference Genes for Gene Expression Studies in Different Genotypes and TRV-Infected Fruits of Peach (Prunus persica L. Batsch) during Ripening

Genes, 2022
Real-time quantitative PCR (RT-qPCR) is a powerful tool to detect and quantify transcription abundance, and the stability of the reference gene determines its success.
Ze Xu, Jieyu Dai, Weijing Su, Haixia Wu, Kamran Shah, L. Xing, Juan-Juan Ma, Dong Zhang, Caiping Zhao   +8 more
semanticscholar   +1 more source

Candidate HKGs in BestKeeper evaluation.

, 2014
Ranking of candidate HKGs by BestKeeper for each brain structure and all structures together, as described by total. Higher correlation coefficients (R) indicate more stable genes.
Juliana Cini Perry (640841), Jair Ribeiro Chagas (640842), Guilherme Silva Julian (640839), Renato Watanabe de Oliveira (640840), Sergio Tufik (74924)   +4 more
core   +1 more source

Analysis of eight candidate reference genes using the Bestkeeper algorithm.

, 2020
Analysis of eight candidate reference genes using the Bestkeeper algorithm.
Fenling Bai (8362935), Bianxia Bai (8362929), Lin Hao (1597876), Jiahong Ren (8362932)   +3 more
core   +1 more source

Innovative In Vivo Approaches to Bone Regeneration: Combining Chitosan‐Xanthan Gum Membranes, Electrical Stimulation, and Laser Therapy

Journal of Biomedical Materials Research Part A, Volume 114, Issue 9, September 2026.
ABSTRACT Critical bone defects present significant clinical challenges due to their debilitating nature and associated costs. Tissue engineering offers a promising solution, employing biomaterials like porous chitosan (CH) and xanthan gum (XG) membranes as scaffolds for tissue regeneration.
Julia Eduarda Schneider Gregório, Renata Francielle Bombaldi de Souza, Maisa Campagnollo, Gláucia Maria Tech dos Santos, Fernanda Carla Bombaldi de Souza, Ângela Maria Moraes, Milton Santamaria‐Jr, Guilherme Ferreira Caetano   +7 more
wiley   +1 more source