Results 21 to 30 of about 14,906 (242)
Decorin knockdown is beneficial for aged tendons in the presence of biglycan expression
Matrix Biology Plus, 2022 Decorin and biglycan are two major small leucine-rich proteoglycans (SLRPs) present in the tendon extracellular matrix that facilitate collagen fibrillogenesis, tissue turnover, and cell signal transduction.
Zakary M. Beach +8 more
doaj +1 more source
Breast cancer dataset with biomarker Biglycan
Data in Brief, 2023 تتكون مجموعة البيانات هذه من صور مجهرية للتعبير الكيميائي المناعي للبيغليكان (BGN) في أنسجة الثدي، مع السرطان وبدونه، باستخدام فقط تلطيخ 3-3'diaminobenzidine (DAB)، بعد معالجة الصور باستخدام مكون إضافي لإزالة الالتفاف اللوني، من Image J. تم الحصول على تعبير DAB الكيميائي المناعي للبيغليكان (BGN) باستخدام الجسم المضاد أحادي النسيلة (M01) (استنساخ 4E1 ...
Pedro Clarindo da Silva Neto +4 more
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Biglycan deletion alters adiponectin expression in murine adipose tissue and 3T3-L1 adipocytes. [PDF]
PLoS ONE, 2012 Obesity promotes increased secretion of a number of inflammatory factors from adipose tissue. These factors include cytokines and very lately, extracellular matrix components (ECM). Biglycan, a small leucine rich proteoglycan ECM protein, is up-regulated
Meliza G Ward, Kolapo M Ajuwon
doaj +1 more source
Transcriptional Regulation of the Human Biglycan Gene [PDF]
Journal of Biological Chemistry, 1996 The small leucine-rich proteoglycan biglycan is involved in several physiological and pathophysiological processes through the ability of its core protein to interact with other extracellular matrix molecules and transforming growth factor-beta (TGF-beta).
Hendrik Ungefroren, Nora Krull
openalex +3 more sources
Journal of Histochemistry & Cytochemistry, 2012 Research over the past few years has provided fascinating results indicating that biglycan, besides being a ubiquitous structural component of the extracellular matrix (ECM), may act as a signaling molecule. Proteolytically released from the ECM, biglycan acts as a danger signal signifying tissue stress or injury.
Năstase, Mădălina-Viviana +2 more
openaire +4 more sources
The cleavage of biglycan by aggrecanases [PDF]
Osteoarthritis and Cartilage, 2006 Aggrecanase-1 [a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)-4] and aggrecanase-2 (ADAMTS-5) have been named for their ability to degrade the proteoglycan aggrecan. While this may be the preferred substrate for these enzymes, they are also able to degrade other proteins.
Melching, L.I. +4 more
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European Journal of Histochemistry, 2020 The gene expression and protein synthesis of small leucine-rich proteoglycans (SLRPs), including decorin, biglycan, fibromodulin, and lumican, was analyzed in the context of the hypothesis that they are closely related to tooth formation.
Angammana Randilini +2 more
doaj +1 more source
WISP-1 Binds to Decorin and Biglycan [PDF]
Journal of Biological Chemistry, 2001 Wnt-1-induced secreted protein 1 (WISP-1) is a member of the CCN (connective tissue growth factor, Cyr61, NOV) family of growth factors. Structural and experimental evidence suggests that CCN family member activities are modulated by their interaction with sulfated glycoconjugates.
L, Desnoyers, D, Arnott, D, Pennica
openaire +2 more sources
Biglycan Regulates MG63 Osteosarcoma Cell Growth Through a LPR6/β-Catenin/IGFR-IR Signaling Axis
Frontiers in Oncology, 2018 Biglycan, a small leucine rich proteoglycan (SLRP), is an important participant in bone homeostasis and development as well as in bone pathology. In the present study biglycan was identified as a positive regulator of MG63 osteosarcoma cell growth (p ≤ 0.
John Aggelidakis +6 more
doaj +1 more source
Identification, characterization and expression analysis of biglycan in asian elephant (elephas maximus) [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2017 The aims of this study were to investigate the coding sequence and the deduced amino acid sequence of Asian elephant"s biglycan gene as well as its expression in different tissues and conditions using wound healing as a model.
Siriwadee CHOMDEJ +10 more
doaj +1 more source