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Serum Metabolomic Signatures Indicate Oxidative Membrane Lipid Remodeling in β-Thalassemia. [PDF]

open access: yesMetabolites
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Bile acid analysis in human disorders of bile acid biosynthesis

Molecular Aspects of Medicine, 2017
Bile acids facilitate the absorption of lipids in the gut, but are also needed to maintain cholesterol homeostasis, induce bile flow, excrete toxic substances and regulate energy metabolism by acting as signaling molecules. Bile acid biosynthesis is a complex process distributed across many cellular organelles and requires at least 17 enzymes in ...
Frédéric M Vaz, Sacha Ferdinandusse
exaly   +4 more sources

Regulation of Bile Acid Biosynthesis

Current Pharmaceutical Design, 1997
Abstract: An elevated concentration of low density lipoprotein (LDL) cholesterol is an independent risk factor for cardiovascular disease. The only quantitatively significant way by which cholesterol is removed from the body is via the bile, either directly or after conversion to bile acids. Therapeutic modalities which increase bile acid biosynthesis,
Hans M G Princen, Sabine M Post
exaly   +3 more sources

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