Results 11 to 20 of about 57,618 (156)

Bile salt biotransformations by human intestinal bacteria

open access: yesJournal of Lipid Research, 2006
Secondary bile acids, produced solely by intestinal bacteria, can accumulate to high levels in the enterohepatic circulation of some individuals and may contribute to the pathogenesis of colon cancer, gallstones, and other gastrointestinal (GI) diseases.
Jason M. Ridlon   +2 more
doaj   +3 more sources

Bile Salt and FGF19 Signaling in the Early Phase of Human Liver Regeneration

open access: yesHepatology Communications, 2021
The involvement of bile salt–fibroblast growth factor 19 (FGF19) signaling in human liver regeneration (LR) is not well studied. Therefore, we studied aspects of bile salt–FGF19 signaling shortly after liver resection in patients. We compared plasma bile
Kiran V.K. Koelfat   +10 more
doaj   +1 more source

A new insight into the physiological role of bile salt hydrolase among intestinal bacteria from the genus Bifidobacterium. [PDF]

open access: yesPLoS ONE, 2014
This study analyzes the occurrence of bile salt hydrolase in fourteen strains belonging to the genus Bifidobacterium. Deconjugation activity was detected using a plate test, two-step enzymatic reaction and activity staining on a native polyacrylamide gel.
Piotr Jarocki   +3 more
doaj   +1 more source

The economy of the enterohepatic circulation of bile acids in the baboon. 1. Studies of controlled enterohepatic circulation of bile acids.

open access: yesJournal of Lipid Research, 1984
A primate model with controlled enterohepatic circulation has been developed which allowed short-term evaluation of bile salt pool size, cycling frequency, and fecal losses.
R N Redinger, J W Hawkins, D M Grace
doaj   +1 more source

Identification of Bile Salt Hydrolase and Bile Salt Resistance in a Probiotic Bacterium Lactobacillus gasseri JCM1131T

open access: yesMicroorganisms, 2021
Lactobacillus gasseri is one of the most likely probiotic candidates among many Lactobacillus species. Although bile salt resistance has been defined as an important criterion for selection of probiotic candidates since it allows probiotic bacteria to ...
Hiroyuki Kusada   +2 more
doaj   +1 more source

Distribution of mixtures of bile salt taurine conjugates between lecithin-cholesterol vesicles and aqueous media: an empirical model

open access: yesJournal of Lipid Research, 1997
Bile salts are surfactants that partition into phospholipid bilayers. When liposomes or membranes are exposed to mixed solutions of bile salts, the more hydrophobic bile salt species associate preferentially with the lipid bilayer.
D M Heuman
doaj   +1 more source

Role of bile salt hydrophobicity in hepatic microtubule-dependent bile salt secretion

open access: yesJournal of Lipid Research, 1994
Under basal conditions, bile salt secretion by the liver is not affected by microtubule disruption. However, when a bile salt load is imposed on the liver, a microtubule-dependent secretion mechanism is recruited (J. Lipid Res. 1988. 29: 144-156).
J M Crawford   +3 more
doaj   +1 more source

A phylogenetic survey of biliary lipids in vertebrates1,

open access: yesJournal of Lipid Research, 2005
Biliary lipids (bile salts, phospholipids, cholesterol, plant sterols) were determined in 89 vertebrate species (cartilaginous and bony fish, reptiles, birds, and mammals), and individual phospholipid classes were measured in 35 species.
Antonio Moschetta   +10 more
doaj   +1 more source

Evolution of substrate specificity for the bile salt transporter ASBT (SLC10A2)[S]

open access: yesJournal of Lipid Research, 2012
The apical Na+-dependent bile salt transporter (ASBT/SLC10A2) is essential for maintaining the enterohepatic circulation of bile salts. It is not known when Slc10a2 evolved as a bile salt transporter or how it adapted to substantial changes in bile salt ...
Daniël A. Lionarons   +2 more
doaj   +1 more source

Taurocholate is more potent than cholate in suppression of bile salt synthesis in the rat

open access: yesJournal of Lipid Research, 1983
Synthesis of bile salts is regulated through negative feedback inhibition by bile salts returning to the liver. Individual bile salts have not been distinguished with regard to inhibitory potential. We assessed inhibition of bile salt synthesis by either
J M Pries   +3 more
doaj   +1 more source

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