Results 11 to 20 of about 57,618 (156)
Bile salt biotransformations by human intestinal bacteria
Secondary bile acids, produced solely by intestinal bacteria, can accumulate to high levels in the enterohepatic circulation of some individuals and may contribute to the pathogenesis of colon cancer, gallstones, and other gastrointestinal (GI) diseases.
Jason M. Ridlon +2 more
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Bile Salt and FGF19 Signaling in the Early Phase of Human Liver Regeneration
The involvement of bile salt–fibroblast growth factor 19 (FGF19) signaling in human liver regeneration (LR) is not well studied. Therefore, we studied aspects of bile salt–FGF19 signaling shortly after liver resection in patients. We compared plasma bile
Kiran V.K. Koelfat +10 more
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A new insight into the physiological role of bile salt hydrolase among intestinal bacteria from the genus Bifidobacterium. [PDF]
This study analyzes the occurrence of bile salt hydrolase in fourteen strains belonging to the genus Bifidobacterium. Deconjugation activity was detected using a plate test, two-step enzymatic reaction and activity staining on a native polyacrylamide gel.
Piotr Jarocki +3 more
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A primate model with controlled enterohepatic circulation has been developed which allowed short-term evaluation of bile salt pool size, cycling frequency, and fecal losses.
R N Redinger, J W Hawkins, D M Grace
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Lactobacillus gasseri is one of the most likely probiotic candidates among many Lactobacillus species. Although bile salt resistance has been defined as an important criterion for selection of probiotic candidates since it allows probiotic bacteria to ...
Hiroyuki Kusada +2 more
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Bile salts are surfactants that partition into phospholipid bilayers. When liposomes or membranes are exposed to mixed solutions of bile salts, the more hydrophobic bile salt species associate preferentially with the lipid bilayer.
D M Heuman
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Role of bile salt hydrophobicity in hepatic microtubule-dependent bile salt secretion
Under basal conditions, bile salt secretion by the liver is not affected by microtubule disruption. However, when a bile salt load is imposed on the liver, a microtubule-dependent secretion mechanism is recruited (J. Lipid Res. 1988. 29: 144-156).
J M Crawford +3 more
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A phylogenetic survey of biliary lipids in vertebrates1,
Biliary lipids (bile salts, phospholipids, cholesterol, plant sterols) were determined in 89 vertebrate species (cartilaginous and bony fish, reptiles, birds, and mammals), and individual phospholipid classes were measured in 35 species.
Antonio Moschetta +10 more
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Evolution of substrate specificity for the bile salt transporter ASBT (SLC10A2)[S]
The apical Na+-dependent bile salt transporter (ASBT/SLC10A2) is essential for maintaining the enterohepatic circulation of bile salts. It is not known when Slc10a2 evolved as a bile salt transporter or how it adapted to substantial changes in bile salt ...
Daniël A. Lionarons +2 more
doaj +1 more source
Taurocholate is more potent than cholate in suppression of bile salt synthesis in the rat
Synthesis of bile salts is regulated through negative feedback inhibition by bile salts returning to the liver. Individual bile salts have not been distinguished with regard to inhibitory potential. We assessed inhibition of bile salt synthesis by either
J M Pries +3 more
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