Results 11 to 20 of about 17,092 (277)
Nature Reviews Methods Primers, 2021 Bioorthogonal chemistry represents a class of high-yielding chemical reactions that proceed rapidly and selectively in biological environments without side reactions towards endogenous functional groups.
Samuel L. Scinto +13 more
semanticscholar +8 more sources
Not So Bioorthogonal Chemistry [PDF]
Journal of the American
Chemical SocietyThe advent of bioorthogonal chemistry has transformed scientific research, offering a powerful tool for selective and noninvasive labeling of (bio)molecules within complex biological environments.
Dominik Schauenburg, Tanja Weil
semanticscholar +7 more sources
Bioorthogonal Chemistry of Polyoxometalates – Challenges and Prospects [PDF]
Chemical Science, 2023 Bioorthogonal chemistry enabled scientists to carry out controlled chemical processes in high yields in vivo while minimizing hazardous effects. Its extension to the field of polyoxometalates (POMs) could open up new possibilities and new applications in molecular electronics, sensing and catalysis, including inside living cells.
Stanislav K. Petrovskii +2 more
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Bioorthogonal Catalysis Goes Chiral [PDF]
Chem, 2020 Bioorthogonal nanofactories have emerged in the last decade to provide xenobiotic pathways that generate nonbiological substances in living environments. In this issue of Chem, Qu and co-workers incorporate asymmetric catalytic properties and chemotactic capabilities into novel nanodevices to achieve the stereo- and site-selective synthesis of the ...
Santamaría, Jesús +1 more
openaire +3 more sources
Click-Triggered Bioorthogonal Bond-Cleavage Reactions [PDF]
Topics in current chemistryBioorthogonal bond-cleavage reactions have evolved into powerful tools for chemical biology, representing a promising strategy for achieving controlled release of molecules under physiologically relevant conditions, even in living organisms.
Patrick Keppel +2 more
semanticscholar +2 more sources
Bioorthogonal Reactions in Animals
ChemBioChem, 2020 AbstractThe advent of bioorthogonal chemistry has led to the development of powerful chemical tools that enable increasingly ambitious applications. In particular, these tools have made it possible to achieve what is considered to be the holy grail of many researchers involved in chemical biology: to perform unnatural chemical reactions within living ...
Karine Porte +5 more
core +5 more sources
Journal of the American Chemical Society, 2023 Personalized tumor vaccines have become a promising modality for cancer immunotherapy. However, in situ personalized tumor vaccines generated from immunogenic cancer cell death (ICD) and adjuvants are mired by toxic side effects and unsatisfactory ...
Mengyu Sun +5 more
semanticscholar +2 more sources
Bioorthogonal chemistry in bioluminescence imaging
Drug Discovery Today, 2018 Bioorthogonal chemistry has developed significant over the past few decades, to the particular benefit of molecular imaging. Bioluminescence imaging (BLI) along with other imaging modalities have significantly benefitted from this chemistry. Here, we review bioorthogonal reactions that have been used to signific antly broaden the application range of ...
Aurélien Godinat +2 more
openaire +4 more sources
Transforming Aryl-Tetrazines into Bioorthogonal Scissors for Systematic Cleavage of trans-Cyclooctenes. [PDF]
Angewandte ChemieBioorthogonal bond-cleavage reactions have emerged as a powerful tool for precise spatiotemporal control of (bio)molecular function in the biological context.
M. Wilkovitsch +13 more
semanticscholar +3 more sources
Advanced ScienceTraditional high‐dose antibiotic treatments of intracellular methicillin‐resistant staphylococcus aureus (MRSA) are highly inefficient and associated with a high rate of infection relapse.
Jianye Yang +9 more
doaj +2 more sources