Results 21 to 30 of about 1,215,519 (212)
Site-Specific Protein Bioconjugation Through Cellular Incorporation of Noncanonical Amino Acids. [PDF]
Angew Chem Int Ed EnglGenetic code expansion (GCE) enables site‐specific installation of noncanonical amino acids containing bioorthogonal conjugation handles, allowing precise, homogeneous protein modification. This review examines the principles of orthogonal translation, surveys the chemistries available for chemoselective labeling, and highlights emerging multi‐site ...
Sarkar R, Joshi M, Chatterjee A.
europepmc +3 more sources
Tetrazine bioorthogonal chemistry derived in vivo imaging
Frontiers in Molecular Biosciences, 2022 Bioorthogonal chemistry represents plenty of highly efficient and biocompatible reactions that proceed selectively and rapidly in biological situations without unexpected side reactions towards miscellaneous endogenous functional groups.
Gaoxiang Zhao +9 more
doaj +1 more source
Bioorthogonal Chemistry of Polyoxometalates – Challenges and Prospects [PDF]
, 2023 Bioorthogonal chemistry enabled scientists to carry out controlled chemical processes in high yields in vivo while minimizing hazardous effects. Its extension to the field of polyoxometalates (POMs) could open up new possibilities and new applications in
Stanislav K., Petrovskii +2 more
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Data-Driven Identification of Metal-free Orthogonal Bioorthogonal Cycloaddition Pairs [PDF]
, 2022 Mutually orthogonal bioorthogonal reactions are a thriving area of research in chemical biology. Here we present a predictive-driven approach to identify mutually orthogonal pairs among two bioorthogonal reactions: the metal-free 1,3-dipolar ...
Jaime, A. S. Coelho +1 more
core +2 more sources
Signal Transduction and Targeted Therapy, 2022 Bioorthogonal chemistry reactions occur in physiological conditions without interfering with normal physiological processes. Through metabolic engineering, bioorthogonal groups can be tagged onto cell membranes, which selectively attach to cargos with ...
Wenzhe Yi +10 more
doaj +1 more source
Bioorthogonal chemistry. [PDF]
, 2021 Bioorthogonal chemistry represents a class of high-yielding chemical reactions that proceed rapidly and selectively in biological environments without side reactions towards endogenous functional groups.
Robillard, Marc S +27 more
core +1 more source
Nanozymes with bioorthogonal reaction for intelligence nanorobots
Biophysics Reports, 2021 Bioorthogonal reactions have attained great interest and achievements in various fields since its first appearance in 2003. Compared to traditional chemical reactions, bioorthogonal chemical reactions mediated by transition metals catalysts can occur under physiological conditions in the living system without interfering with or damaging other ...
Sun, Si +4 more
openaire +2 more sources
Bioorthogonal Ligations and Cleavages in Chemical Biology
ChemistryOpen, 2020 Bioorthogonal reactions including the bioorthogonal ligations and cleavages have become an active field of research in chemical biology, and they play important roles in chemical modification and functional regulation of biomolecules.
Youshan Li, Prof. Dr. Hua Fu
doaj +1 more source
A Genetically Encoded Isonitrile Lysine for Orthogonal Bioorthogonal Labeling Schemes
Molecules, 2021 Bioorthogonal click-reactions represent ideal means for labeling biomolecules selectively and specifically with suitable small synthetic dyes. Genetic code expansion (GCE) technology enables efficient site-selective installation of bioorthogonal handles ...
Ágnes Szatmári +8 more
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Characterization of an N-Allylglyoxylamide Based Bioorthogonal Nitrone Trap [PDF]
, 2023 Aldehydes are attractive bioorthogonal coupling partners. The ease of manipulation of aldehydes and their orthogonality to other classes of bioorthogonal reactions has inspired the exploration of chemistries which generate irreversible conjugates ...
Hunter, Clark +7 more
core +2 more sources