Results 1 to 10 of about 42,861 (236)
Prochiral pyrmetazole can be asymmetrically oxidized into (S)-omeprazole, a proton pump inhibitor that is used to treat gastroesophageal reflux, by an engineered cyclohexanone monooxygenase (CHMO Acineto -Mut) that has high stereoselectivity.
Ya-Jing Li +6 more
doaj +1 more source
Highlight Efficiency of bioreduction of sulfate and biomass can be increased by CdS NPs. It is important for the EPS of RSB to improve the sulfate reduction efficiency. Utilization efficiency of extracellular electrons by RSB can be enhanced through EPS.
Guoqing Cheng +6 more
doaj +1 more source
Vitamin combination promotes ex vivo expansion of NK-92 cells by reprogramming glucose metabolism
Robust ex vivo expansion of NK-92 cells is essential for clinical immunotherapy. The vitamin B group is critical for the expansion and function of immune cells.
Yan Fu +5 more
doaj +1 more source
Enhancement of fatty acid degradation pathway promoted glucoamylase synthesis in Aspergillus niger
Background Our recent multi-omics analyses of glucoamylase biosynthesis in Aspergillus niger (A. niger) suggested that lipid catabolism was significantly up-regulated during high-yield period under oxygen limitation.
Jie Qi +5 more
doaj +1 more source
De novo synthesis of nervonic acid and optimization of metabolic regulation by Yarrowia lipolytica
Nervonic acid, a natural fatty acid compound and also a core component of nerve fibers and nerve cells, has been widely used to prevent and treat related diseases of the brain nervous system.
Xin-Ru Zhao +6 more
doaj +1 more source
FLOCCULATION BIOREACTORS [PDF]
One of the main goals of bioprocess engineering is to increase the productivity of biotechnological processes and a vigorous progress has been observed in that field over the last decades. Fermentation based processes are not an exception and, in order to achieve those objectives, techniques such as the use of high cell density systems have been ...
Vicente, A. A. +2 more
openaire +2 more sources
Expression of recombinant human Apolipoprotein A-IMilano in Nicotiana tabacum
Apolipoprotein A-IMilano (Apo A-IMilano) is a natural mutant of Apolipoprotein. It is currently the only protein that can clear arterial wall thrombus deposits and promptly alleviate acute myocardial ischemia.
Wei Zhao +9 more
doaj +1 more source
Ansamitocin P-3 (AP-3) produced by Actinosynnema pretiosum is a potent antitumor agent. However, lack of efficient genome editing tools greatly hinders the AP-3 overproduction in A. pretiosum.
Siyu Guo +6 more
doaj +1 more source
During the ex vivo expansion of umbilical cord-derived mesenchymal stem cells (hUCMSCs) in a stirred tank bioreactor, the formation of cell–microcarrier aggregates significantly affects cell proliferation and physiological activity, making it difficult ...
Botao Zhang +6 more
doaj +1 more source
Background Compared with shake flask, bioreactor offers a relatively stable and controllable extracellular environment for cell growth and metabolism.
Xiwei Tian +8 more
doaj +1 more source

