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Optimization of oxygen transfer and power consumption in aerobic bioprocess by designing disc turbine impeller based on CFD-Taguchi method. [PDF]
Sci RepDisc turbine impeller serves as a vital component of stirred-tank bioreactors and plays crucial role in optimizing their performance. This research integrates Computational Fluid Dynamics (CFD) with Taguchi experimental method to analyze the effects of ...
Gu Q +5 more
europepmc +2 more sources
Bioresources and Bioprocessing, 2021 Prochiral pyrmetazole can be asymmetrically oxidized into (S)-omeprazole, a proton pump inhibitor that is used to treat gastroesophageal reflux, by an engineered cyclohexanone monooxygenase (CHMO Acineto -Mut) that has high stereoselectivity.
Ya-Jing Li +6 more
doaj +1 more source
Bioresources and Bioprocessing, 2022 Highlight Efficiency of bioreduction of sulfate and biomass can be increased by CdS NPs. It is important for the EPS of RSB to improve the sulfate reduction efficiency. Utilization efficiency of extracellular electrons by RSB can be enhanced through EPS.
Guoqing Cheng +6 more
doaj +1 more source
Vitamin combination promotes ex vivo expansion of NK-92 cells by reprogramming glucose metabolism
Bioresources and Bioprocessing, 2022 Robust ex vivo expansion of NK-92 cells is essential for clinical immunotherapy. The vitamin B group is critical for the expansion and function of immune cells.
Yan Fu +5 more
doaj +1 more source
Enhancement of fatty acid degradation pathway promoted glucoamylase synthesis in Aspergillus niger
Microbial Cell Factories, 2022 Background Our recent multi-omics analyses of glucoamylase biosynthesis in Aspergillus niger (A. niger) suggested that lipid catabolism was significantly up-regulated during high-yield period under oxygen limitation.
Jie Qi +5 more
doaj +1 more source
De novo synthesis of nervonic acid and optimization of metabolic regulation by Yarrowia lipolytica
Bioresources and Bioprocessing, 2023 Nervonic acid, a natural fatty acid compound and also a core component of nerve fibers and nerve cells, has been widely used to prevent and treat related diseases of the brain nervous system.
Xin-Ru Zhao +6 more
doaj +1 more source
Expression of recombinant human Apolipoprotein A-IMilano in Nicotiana tabacum
Bioresources and Bioprocessing, 2023 Apolipoprotein A-IMilano (Apo A-IMilano) is a natural mutant of Apolipoprotein. It is currently the only protein that can clear arterial wall thrombus deposits and promptly alleviate acute myocardial ischemia.
Wei Zhao +9 more
doaj +1 more source
Magnetic-driven dynamic culture promotes osteogenesis of mesenchymal stem cell
Bioresources and Bioprocessing, 2021 Effective nutrient transport and appropriate mechanical stimulation play important roles in production of tissue-engineered bone grafts. In this study, an experimental set-up for magnetic-driven dynamic culture of cells was designed to mimic the ...
Mengyang Hao +4 more
doaj +1 more source
Bioresources and Bioprocessing, 2018 Background Compared with shake flask, bioreactor offers a relatively stable and controllable extracellular environment for cell growth and metabolism.
Xiwei Tian +8 more
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Multi-omics analysis defines 5-fluorouracil drug resistance in 3D HeLa carcinoma cell model
Bioresources and Bioprocessing, 2021 Cervical cancer is a serious health problem in women around the globe. However, the use of clinical drug is seriously dampened by the development of drug resistance.
Lin Wang +4 more
doaj +1 more source