Results 11 to 20 of about 72,831 (298)
Bioresources and Bioprocessing, 2018 Background Compared with shake flask, bioreactor offers a relatively stable and controllable extracellular environment for cell growth and metabolism.
Xiwei Tian +8 more
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Nature Communications, 2018 In humans, caspase-5 is an LPS sensor that can induce gasdermin D cleavage and pyroptosis. Here, the authors show that zebrafish caspy2 is a functional homolog as it also senses cytosolic LPS to activate the noncanonical inflammasome and to protect ...
Dahai Yang +13 more
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Stem Cell Research & Therapy, 2019 Background Adipose-derived mesenchymal stem cells (ADMSCs) are considered an efficient and important candidate for male infertility treatment because they contain pluripotent stem cells, which can differentiate into all cells from three germ layers ...
Yanxia Luo +9 more
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Dynamic response of Aspergillus niger to single pulses of glucose with high and low concentrations
Bioresources and Bioprocessing, 2019 Microorganisms generally encounter a fluctuating environment in their natural habitat and similar conditions also happen in large-scale bioreactors. In this work, the dynamic response of intracellular and extracellular metabolites of Aspergillus niger ...
Shuai Wang +7 more
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Bioresources and Bioprocessing, 2022 Ansamitocin P-3 (AP-3) produced by Actinosynnema pretiosum is a potent antitumor agent. However, lack of efficient genome editing tools greatly hinders the AP-3 overproduction in A. pretiosum.
Siyu Guo +6 more
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Bioresources and Bioprocessing, 2023 During the ex vivo expansion of umbilical cord-derived mesenchymal stem cells (hUCMSCs) in a stirred tank bioreactor, the formation of cell–microcarrier aggregates significantly affects cell proliferation and physiological activity, making it difficult ...
Botao Zhang +6 more
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Operation of a Benchtop Bioreactor [PDF]
Journal of Visualized Experiments, 2013 Fermentation systems are used to provide an optimal growth environment for many different types of cell cultures. The ability afforded by fermentors to carefully control temperature, pH, and dissolved oxygen concentrations in particular makes them essential to efficient large scale growth and expression of fermentation products. This video will briefly
Patrick J. Cummings +2 more
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FLOCCULATION BIOREACTORS [PDF]
, 2010 One of the main goals of bioprocess engineering is to increase the productivity of biotechnological processes and a vigorous progress has been observed in that field over the last decades. Fermentation based processes are not an exception and, in order to achieve those objectives, techniques such as the use of high cell density systems have been ...
Vicente, A. A. +2 more
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Plant Bioreactors for Pharmaceuticals [PDF]
Biotechnology and Genetic Engineering Reviews, 2008 Plant bioreactors are attractive expression systems for economic production of pharmaceuticals. Various plant expression systems or platforms have been tested with certain degrees of success over the past years. However, further development and improvement are needed for more effective plant bioreactors.
Liwen Jiang +4 more
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Bioresources and Bioprocessing, 2018 Background Charge heterogeneity is one of the most critical quality attributes of antibodies, which has strong influence on drug’s biological activity and safety.
Huijie Niu +7 more
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