Anti-cancer activity of novel dibenzo[b,f]azepine tethered isoxazoline derivatives [PDF]
10.1186/1472-6769-12-5BMC Chemical ...
Anilkumar, N.C. +10 more
core +3 more sources
Cyanide, An Environmental Inhibitor of Predation by Bdellovibrio bacteriovorus HD100 [PDF]
Department of Biological SciencesBALOs are predatory bacteria attacking specific Gram-negative prey bacteria and have been studied about both their life itself and their possibility to be used as alternatives to antibiotics.
Kwon, HeeUn
core
Antibacterial activities of selected edible plants extracts against multidrug-resistant Gram-negative bacteria [PDF]
BACKGROUND: In response to the propagation of bacteria resistant to many antibiotics also called multi-drug resistant (MDR) bacteria, the discovery of new and more efficient antibacterial agents is primordial.
Aimé G Fankam +7 more
core +1 more source
From data to discovery: leveraging big data in plant natural products biosynthesis research
SUMMARY Plant natural products or specialized metabolites play a vital role in drug discovery and development, with many clinically important derivatives such as the anticancer drugs topotecan (derived from the natural alkaloid camptothecin) and etoposide (derived from the natural polyphenol podophyllotoxin).
Matthew McConnachie +4 more
wiley +1 more source
Bisindolyl alkaloids represent a large family of natural and synthetic products that display various biological activities. Among the bisindole compounds, 6,7,12,13-tetrahydro-5H-cyclohepta[2,1-b:3,4-b’]diindoles have received little attention ...
Lei Peng, Xiaofei Zhang, Chunhao Yang
doaj +1 more source
Production of the Bioactive Compounds Violacein and Indolmycin Is Conditional in a maeA Mutant of Pseudoalteromonas luteoviolacea S4054 Lacking the Malic Enzyme [PDF]
Copyright © 2016 Thøgersen, Delpin, Melchiorsen, Kilstrup, Månsson, Bunk, Spröer, Overmann, Nielsen and Gram. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Boyke Bunk +11 more
core +2 more sources
Chapter 3 Noniridoid Bisindole Alkaloids
This chapter discusses that indole is a reactive nucleus prone to dimerization when it is isolated or a part of tryptamine or tryptophan, which themselves are reactive toward many functionalities. For these reasons, bisindoles, the majority of which are of iridoid origin, are frequently isolated in nature. Besides these “dimers,” there exists a growing
Sapi, J., Massiot, G.
openaire +1 more source
Antimicrobial, antimycobacterial and antibiofilm properties of Couroupita guianensis Aubl. fruit extract [PDF]
BACKGROUND: Couroupita guianensis Aubl. (Lecythidaceae) is commonly called Ayahuma and the Cannonball tree. It is distributed in the tropical regions of northern South America and Southern Caribbean. It has several medicinal properties.
Chandrasekar Balachandran +7 more
core +1 more source
Abstract The synthesis of architecturally complex polyheterocyclic structures embedding the indole ring represents a growing field of interest. Carbolines and their partially dehydro derivatives, pyrazinoindoles, indoloindoles, azepinoindoles and other medium‐sized derivatives are only some examples of indole‐containing polycyclic compounds featured by
Alessandro Palmieri, Marino Petrini
wiley +1 more source
Circular dichroism calculation for natural products [PDF]
Determination of the absolute configuration (AC) is often a challenging aspect in the structure elucidation of natural products. When chiral compounds possess appropriate chromophore(s), electronic circular dichroism (ECD) may provide a powerful approach
Alfarius Eko Nugroho, Hiroshi Morita
core +1 more source

