Results 71 to 80 of about 2,460 (195)

Anti-cancer activity of novel dibenzo[b,f]azepine tethered isoxazoline derivatives [PDF]

open access: yes, 2012
10.1186/1472-6769-12-5BMC Chemical ...
Anilkumar, N.C.   +10 more
core   +3 more sources

Cyanide, An Environmental Inhibitor of Predation by Bdellovibrio bacteriovorus HD100 [PDF]

open access: yes, 2017
Department of Biological SciencesBALOs are predatory bacteria attacking specific Gram-negative prey bacteria and have been studied about both their life itself and their possibility to be used as alternatives to antibiotics.
Kwon, HeeUn
core  

Antibacterial activities of selected edible plants extracts against multidrug-resistant Gram-negative bacteria [PDF]

open access: yes, 2013
BACKGROUND: In response to the propagation of bacteria resistant to many antibiotics also called multi-drug resistant (MDR) bacteria, the discovery of new and more efficient antibacterial agents is primordial.
Aimé G Fankam   +7 more
core   +1 more source

From data to discovery: leveraging big data in plant natural products biosynthesis research

open access: yesThe Plant Journal, Volume 122, Issue 6, June 2025.
SUMMARY Plant natural products or specialized metabolites play a vital role in drug discovery and development, with many clinically important derivatives such as the anticancer drugs topotecan (derived from the natural alkaloid camptothecin) and etoposide (derived from the natural polyphenol podophyllotoxin).
Matthew McConnachie   +4 more
wiley   +1 more source

Convenient Synthesis of 6,7,12,13-Tetrahydro-5H-Cyclohepta[2,1-b:3,4-b’]diindole Derivatives Mediated by Hypervalent Iodine (III) Reagent

open access: yesMolecules, 2019
Bisindolyl alkaloids represent a large family of natural and synthetic products that display various biological activities. Among the bisindole compounds, 6,7,12,13-tetrahydro-5H-cyclohepta[2,1-b:3,4-b’]diindoles have received little attention ...
Lei Peng, Xiaofei Zhang, Chunhao Yang
doaj   +1 more source

Production of the Bioactive Compounds Violacein and Indolmycin Is Conditional in a maeA Mutant of Pseudoalteromonas luteoviolacea S4054 Lacking the Malic Enzyme [PDF]

open access: yes, 2016
Copyright © 2016 Thøgersen, Delpin, Melchiorsen, Kilstrup, Månsson, Bunk, Spröer, Overmann, Nielsen and Gram. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Boyke Bunk   +11 more
core   +2 more sources

Chapter 3 Noniridoid Bisindole Alkaloids

open access: yes, 1995
This chapter discusses that indole is a reactive nucleus prone to dimerization when it is isolated or a part of tryptamine or tryptophan, which themselves are reactive toward many functionalities. For these reasons, bisindoles, the majority of which are of iridoid origin, are frequently isolated in nature. Besides these “dimers,” there exists a growing
Sapi, J., Massiot, G.
openaire   +1 more source

Antimicrobial, antimycobacterial and antibiofilm properties of Couroupita guianensis Aubl. fruit extract [PDF]

open access: yes, 2012
BACKGROUND: Couroupita guianensis Aubl. (Lecythidaceae) is commonly called Ayahuma and the Cannonball tree. It is distributed in the tropical regions of northern South America and Southern Caribbean. It has several medicinal properties.
Chandrasekar Balachandran   +7 more
core   +1 more source

2‐Aminoindoles and 2‐Iminoindolines as Viable Precursors of Indole‐Fused Nitrogenated Polyheterocycles

open access: yesAdvanced Synthesis &Catalysis, Volume 367, Issue 6, March 18, 2025.
Abstract The synthesis of architecturally complex polyheterocyclic structures embedding the indole ring represents a growing field of interest. Carbolines and their partially dehydro derivatives, pyrazinoindoles, indoloindoles, azepinoindoles and other medium‐sized derivatives are only some examples of indole‐containing polycyclic compounds featured by
Alessandro Palmieri, Marino Petrini
wiley   +1 more source

Circular dichroism calculation for natural products [PDF]

open access: yes, 2013
Determination of the absolute configuration (AC) is often a challenging aspect in the structure elucidation of natural products. When chiral compounds possess appropriate chromophore(s), electronic circular dichroism (ECD) may provide a powerful approach
Alfarius Eko Nugroho, Hiroshi Morita
core   +1 more source

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