Results 31 to 40 of about 34,526 (257)

Application of auriculotemporal nerve block and dextrose prolotherapy in exercise therapy of TMJ closed lock in adolescents and young adults

open access: yesHead & Face Medicine, 2021
Background Temporomandibular joint (TMJ) ‘closed lock’ is a clinical condition causing TMJ pain and limited mouth opening (painful locking). Recent studies suggest an increasing prevalence of degenerative joint disease associated with the onset of TMJ ...
Hongzhi Zhou, Yang Xue, Ping Liu
doaj   +1 more source

A field study testing the ability of a sound deterrent system to block the upstream migration of invasive carp through a Mississippi River Lock and Dam

open access: yes, 2020
Plan B paper completed for a MS in Conservation Sciences, Fisheries and Aquatic Biology.Riesgraf, Andrew T. (2020). A field study testing the ability of a sound deterrent system to block the upstream migration of invasive carp through a Mississippi River
Riesgraf, Andrew T
core   +1 more source

Modeling of deformation processes in rock massif in the vicinity of underground goafs considering the formation of discontinuity zones

open access: yesTheoretical and Applied Mechanics Letters, 2020
: The construction of mechanical-mathematical model and numerical method for the deformation processes of rock massifs with goafs and underground structures is very complex and also important task in modern rock mechanics.
Michael Zhuravkov   +2 more
doaj   +1 more source

Mechanism by Which PF-3758309, a Pan Isoform Inhibitor of p21-Activated Kinases, Blocks Reactivation of HIV-1 Latency

open access: yesBiomolecules, 2023
The “block and lock” strategy is one approach that might elicit a sterilizing cure for HIV-1 infection. The “block” refers to a compound’s ability to inhibit latent HIV-1 proviral transcription, while the “lock” refers to its capacity to induce permanent
Benni Vargas   +3 more
doaj   +1 more source

Bike Off 2 – Catalysing Anti Theft Bike, Bike Parking and Information Design for the 21st Century [PDF]

open access: yes, 2008
Project Bikeoff's Design for the 21st Century programme, followed earlier research and development work on preventing bike theft by colleagues at the Design Against Crime Research Centre, my own work over 15 years in developing conceptual frameworks for ...
Ekblom, Paul
core   +1 more source

Data for Evaluation of a broadband sound projected from the gates of a navigation lock in the Mississippi River shows it to be a weak deterrent for common carp and unable to block passage

open access: yes, 2018
See Readme files.There is an urgent need to block the passage of carp and other invasive fishes through navigational locks in large rivers. Although the broadband sound of an outboard motor has been shown to strongly repel three species of carp in ...
Zielinski, Daniel P.   +5 more
core   +1 more source

“Locking” CDK9 inhibition by activating integrator function in HIV transcription

open access: yesiScience
Summary: The positive transcription elongation factor b (P-TEFb) is a critical host factor for HIV transcription, yet pharmacological inhibition of its CDK9 subunit yields transient suppression with cytotoxicity.
Zichong Li   +3 more
doaj   +1 more source

Lock out: targeting TMPRSS2 to block influenza and coronaviruses

open access: yesJournal of Virology
Coronaviruses and influenza A viruses (IAV) can cause severe respiratory disease and have pandemic potential. Both viruses depend on priming of their glycoproteins by host cell proteases for the acquisition of infectivity, and the responsible enzymes ...
Lu Zhang   +2 more
doaj   +1 more source

CounterAKTing HIV: Toward a “Block and Clear” Strategy?

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
The protein kinase B or Akt is a central regulator of survival, metabolism, growth and proliferation of the cells and is known to be targeted by various viral pathogens, including HIV-1.
Sébastien Pasquereau   +2 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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