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The blood-brain barrier.

Journal of neuroradiology = Journal de neuroradiologie, 1990
The blood-brain barrier (BBB) is present on three sites: the brain vessels, the choroid plexus and the arachnoid membrane. It is made of non-fenestrated endothelial or epithelial cells interconnected by tight junctions. Biochemically, the BBB is formed by bimolecular layers of phospholipids into which globular proteins are inserted.
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The Blood-Brain Barrier

Physiological Reviews, 1960
John Dobbing   +3 more
openaire   +5 more sources

A blood-brain barrier in a dish

Nature Methods, 2012
Codifferentiating human pluripotent stem cells along neural and endothelial lineages provides cues to efficiently generate blood-brain barrier endothelial cells.
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Astrocyte–endothelial interactions at the blood–brain barrier

Nature Reviews Neuroscience, 2006
N. Abbott, L. Rönnbäck, E. Hansson
semanticscholar   +1 more source

Blood-brain barrier biomarkers

The blood-brain barrier (BBB) is a dynamic interface that regulates the exchange of molecules and cells between the brain parenchyma and the peripheral blood. The BBB is mainly composed of endothelial cells, astrocytes and pericytes. The integrity of this structure is essential for maintaining brain and spinal cord homeostasis and protection from ...
Juan F, Zapata-Acevedo   +3 more
openaire   +2 more sources

The Blood-Brain Barrier

Scientific American, 1986
G W, Goldstein, A L, Betz
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Blood–brain barrier delivery

Drug Discovery Today, 2007
Neuropharmaceutics is the largest potential growth sector of the pharmaceutical industry. However, this growth is blocked by the problem of the blood-brain barrier (BBB). Essentially 100% of large-molecule drugs and >98% of small-molecule drugs do not cross the BBB. The BBB can be traversed because there are multiple endogenous transporters within this
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The Blood‐Brain Barrier

Developmental Medicine & Child Neurology, 1961
P F, BENSON, M C, JOSEPH
openaire   +2 more sources

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