Results 91 to 100 of about 38,639 (266)
Autophagy and rheumatoid arthritis: Current knowledges and future perspectives [PDF]
, 2018 Autophagy is a degradation mechanism by which cells recycle cytoplasmic components to generate energy. By influencing lymphocyte development, survival, and proliferation, autophagy regulates the immune responses against self and non-self antigens ...
Alessandri, Cristiano +10 more
core +2 more sources
Advanced Science, EarlyView.Schematic illustration of injectable PDA‐modified GelMA microspheres loaded with BioPre‐Exos for vascularized bone regeneration. ABSTRACT Critical‐sized bone defects remain a highly challenging clinical problem due to insufficient intrinsic self‐healing capacity.
Lijun Li +9 more
wiley +1 more source
Bone & Joint ResearchAims: This study aimed to identify and compare the microRNA (miRNA) profiles of exosomes derived from human induced pluripotent stem cells (iPSCs), bone marrow mesenchymal stem cells (BMSCs), and adipose tissue-derived stem cells (ADSCs) (hiPSC-Exos ...
Ling-Hua Chang +11 more
doaj +1 more source
Myosin 1a Regulates Osteoblast Differentiation Independent of Intestinal Calcium Transport. [PDF]
, 2019 Myosin 1A (Myo1a) is a mechanoenzyme previously thought to be located exclusively in the intestinal epithelium. It is the principle calmodulin-binding protein of the brush border.
Bikle, Daniel D +3 more
core
Bioactive SrO-SiO2 glass with well-ordered mesopores: Characterization, physiochemistry and biological properties [PDF]
, 2011 For a biomaterial to be considered suitable for bone repair it should ideally be both bioactive and have a capacity for controllable drug delivery; as such, mesoporous SiO2 glass has been proposed as a new class of bone regeneration material by virtue of
Cuniberti, Gianaurelio +8 more
core +2 more sources
Advanced Science, EarlyView.The graphical abstract image of bamboo‐like whisker‐reinforced Ca‐P bioceramics accelerating large segmental bone regeneration. ABSTRACT Regenerative repair of segmental bone defect remains a major clinical challenge. The conventional mental implants suffer from mechanical strength mismatch and long‐term foreign bodies presence.
Cong Feng +10 more
wiley +1 more source
The effect of mesoporous bioglass on osteogenesis and adipogenesis of osteoporotic BMSCs [PDF]
, 2016 This study evaluated the effect of mesoporous bioglass (MBG) dissolution on the differentiation of bone marrow mesenchymal stem cells (BMSCs) derived from either sham control or ovariectomized (OVX) rats.
Cheng, Ning +5 more
core +1 more source
Mitochondria on the move: BMSCs fuel AML energy [PDF]
Blood, 2017 In this issue of Blood, Marlein et al1 identify a tumor-specific NOX2-dependent transfer of mitochondria from bone marrow stromal cells (BMSCs) to acute myeloid leukemia (AML) cells via AML-derived tunneling nanotubes (see figure), supporting inhibition of NOX2 as a novel therapeutic strategy in AML.
openaire +2 more sources
Advanced Science, EarlyView.Schematic representation of the role of lipophagy in bone mesenchymal stem cells(MSCs). In healthy MSCs, functional lipophagy efficiently degrades lipid droplets to support oxidative phosphorylation and cellular energy production, thereby facilitating osteogenic differentiation and matrix mineralization.
Chaoqiang Chen +8 more
wiley +1 more source
Development of Bone Targeting Drugs. [PDF]
, 2017 The skeletal system, comprising bones, ligaments, cartilage and their connective tissues, is critical for the structure and support of the body. Diseases that affect the skeletal system can be difficult to treat, mainly because of the avascular cartilage
Alméciga-Díaz, Carlos J. +6 more
core +2 more sources