Results 21 to 30 of about 27,592 (167)

Cyclooxygenase-2 negatively regulates osteogenic differentiation in murine bone marrow mesenchymal stem cells via the FOXO3a/p27kip1 pathway

Bone & Joint Research
Aims: Cyclooxygenase-2 (COX-2) is an enzyme that synthesizes prostaglandins from arachidonic acid. Previous reports have indicated that COX-2 is constitutively expressed in osteogenic cells instead of being expressed only after pathogenic induction, and
Shu-Chun Chuang, Ya-Shuan Chou, Yi-Shan Lin, Je-Ken Chang, Chung-Hwan Chen, Mei-Ling Ho   +5 more
doaj   +1 more source

RETRACTED: Hepatoma Cell-Derived Extracellular Vesicles Promote Liver Cancer Metastasis by Inducing the Differentiation of Bone Marrow Stem Cells Through microRNA-181d-5p and the FAK/Src Pathway

Frontiers in Cell and Developmental Biology, 2021
Bone marrow mesenchymal stem cells (BMSCs) are beneficial to repair the damaged liver. Tumor-derived extracellular vesicles (EV) are notorious in tumor metastasis.
Huamei Wei, Huamei Wei, Jianchu Wang, Jianchu Wang, Zuoming Xu, Zuoming Xu, Wenchuan Li, Wenchuan Li, Xianjian Wu, Chenyi Zhuo, Yuan Lu, Xidai Long, Xidai Long, Qianli Tang, Qianli Tang, Jian Pu, Jian Pu   +16 more
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Progress of bone marrow mesenchymal stem cell transplantation on neural plasticity in brain

Frontiers in Cell and Developmental Biology
Stem cells are cells with strong proliferation and differentiation abilities. Among all stem cells, bone marrow mesenchymal stem cells (BMSCs) have been extensively studied.
Wenjing Li, Wenjing Li, Xiaohua Liu, Jingjing Li   +3 more
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Bone mesenchymal stem cells contributed to the neointimal formation after arterial injury. [PDF]

PLoS ONE, 2013
OBJECTIVES: Recent findings suggest that in response to repair-to-injury bone marrow mesenchymal stem cells (BMSCs) participate in the process of angiogenesis. It is unclear what role BMSCs play in the structure of the vessel wall.
Mincai Li, Suqin Li, Liangzhu Yu, Jiliang Wu, Tonghui She, Yaping Gan, Zhenwu Hu, Wenli Liao, Hongli Xia   +8 more
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The Role of Tantalum Nanoparticles in Bone Regeneration Involves the BMP2/Smad4/Runx2 Signaling Pathway

International Journal of Nanomedicine, 2020
Guilan Zhang,1,2 Wenjing Liu,3 Ruolan Wang,1 Yanli Zhang,3 Liangjiao Chen,4 Aijie Chen,3 Haiyun Luo,5 Hui Zhong,1 Longquan Shao1,2 1Department of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, People’s Republic of ...
Zhang G, Liu W, Wang R, Zhang Y, Chen L, Chen A, Luo H, Zhong H, Shao L   +8 more
doaj  

Apoptosis of bone marrow mesenchymal stem cells caused by homocysteine via activating JNK signal. [PDF]

PLoS ONE, 2013
Bone marrow mesenchymal stem cells (BMSCs) are capable of homing to and repair damaged myocardial tissues. Apoptosis of BMSCs in response to various pathological stimuli leads to the attenuation of healing ability of BMSCs.
Benzhi Cai, Xingda Li, Yang Wang, Yanju Liu, Fan Yang, Hongyang Chen, Kun Yin, Xueying Tan, Jiuxin Zhu, Zhenwei Pan, Baoqiu Wang, Yanjie Lu   +11 more
doaj   +1 more source

Propofol nanoparticles promote fracture healing in mice by accelerating cartilage formation

European Cells & Materials
Background: Fracture healing is a process characterized by cartilage formation and subsequent ossification. Propofol, a systemic anesthetic known for its anti-inflammatory and chondrogenic properties, was encapsulated into nanoparticles (NPs) to improve ...
BY Zhang, Z Wang, SJ Yan, H Wang
doaj   +1 more source

Starvation‑induced NEDD4‑mediated autophagy in BMSCs

Biomedical Reports
Autophagy regulates the osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) and mediates BMSC-mediated bone remodeling under pathological conditions (such as osteoporosis and infectious bone defects). However, the regulatory mechanisms controlling autophagy in BMSCs remain unclear.
Liu, Chengyi, Zhang, Shuang, Yun, Xiaoxian, Li, Bo, Xu, Xiaomei, Lin, Fuwei   +5 more
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ASPH Regulates Osteogenic Differentiation and Cellular Senescence of BMSCs [PDF]

Frontiers in Cell and Developmental Biology, 2020
Osteogenesis and senescence of BMSCs play great roles in age-related bone loss. However, the causes of these dysfunctions remain unclear. In this study, we identified a differentially expressed ASPH gene in middle-aged and elderly aged groups which were obtained from GSE35955.
Hui Peng, Qi Guo, Ye Xiao, Tian Su, Tie-Jian Jiang, Li-Juan Guo, Min Wang   +6 more
openaire   +3 more sources

Differentiation of bone marrow derived mesenchymal stem cells into male germ-like cells in co-culture with testicular cells

Endocrine Regulations, 2019
Objective. Stem cell therapy, specifically, pre-induction of mesenchymal stem cells toward male germ-like cells may be useful in patients with azoospermia.
Malekmohamadi Nasim, Abdanipour Alireza, Ghorbanlou Mehrdad, Shokri Saeed, Shirazi Reza, Dimitriadis Eva, Nejatbakhsh Reza   +6 more
doaj   +1 more source