Results 11 to 20 of about 27,592 (167)
Gliko BMSC: A potential strategy of treatment for renal fibrosis
Regenerative Therapy, 2022 Objective: There are many researches on using bone marrow mesenchymal stem cells (BMSCs) in the treatment of acute kidney injury (AKI), which has certain effects, but the mechanism of action is still unclear.
Long Shi +6 more
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Comparison of Muscle Regeneration after BMSC-Conditioned Medium, Syngeneic, or Allogeneic BMSC Injection [PDF]
Cells, 2022 For many years optimal treatment for dysfunctional skeletal muscle characterized, for example, by impaired or limited regeneration, has been searched. Among the crucial factors enabling its development is finding the appropriate source of cells, which could participate in tissue reconstruction or serve as an immunomodulating agent (limiting immune ...
Barbara Świerczek-Lasek +8 more
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THE EFFECT OF NANO-CaCO₃ ON THE PROPERTIES OF BMSC [PDF]
Ceramics - Silikaty, 2021 In this work, to study the effects of different contents of nano-CaCO₃ on the hydration characteristics of a basic magnesium sulfate cement (BMSC), the mechanical properties and water resistance of the BMSC paste were analysed via compressive strength tests and long-term immersion tests. The effect of nano-CaCO₃ on the hydration of the BMSC was studied
Xinghan Jiang +4 more
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Effects of BMSC-Derived EVs on Bone Metabolism
Pharmaceutics, 2022 Extracellular vesicles (EVs) are small membrane vesicles that can be secreted by most cells. EVs can be released into the extracellular environment through exocytosis, transporting endogenous cargo (proteins, lipids, RNAs, etc.) to target cells and thereby triggering the release of these biomolecules and participating in various physiological and ...
Xuchang Zhou +4 more
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Efficiency of Cell Therapy to GC-Induced ONFH: BMSCs with Dkk-1 Interference Is Not Superior to Unmodified BMSCs [PDF]
Stem Cells International, 2018 Glucocorticoid-induced osteonecrosis of the femoral head (ONFH) is a hip disorder, and it threatens patients who require megadose of steroid therapies. Nowadays, no valid therapies can reverse the development of GC-induced ONFH once it occurs. Stem cell therapy to GC-induced ONFH would be a promising choice. Although the pathogenesis of GC-induced ONFH
Wei Zhun +4 more
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Magnesium Enhances Osteogenesis of BMSCs by Tuning Osteoimmunomodulation [PDF]
BioMed Research International, 2019 In the process of bone tissue engineering, the osteoimmunomodulatory property of biomaterials is very important for osteogenic differentiation of stem cells, which determines the outcome of bone regeneration. Magnesium (Mg) is a biodegradable, biocompatible metal that has osteoconductive properties and has been regarded as a promising bone biomaterial.
Xufang Zhang, Qingpiao Chen, Xueli Mao
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Cells, 2022 Osteoporosis, or steroid-induced osteonecrosis of the hip, is accompanied by increased bone marrow adipogenesis. Such a disorder of adipogenic/osteogenic differentiation, affecting bone-marrow-derived mesenchymal stem cells (BMSCs), contributes to bone loss during aging.
Chenglong Wang +7 more
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Bioengineering, 2023 Therapeutic strategies based on utilizing endogenous BMSCs have been developed for the regeneration of bone, cartilage, and ligaments. We previously found that E7 peptide (EPLQLKM) could enhance BMSC homing in bio-scaffolds and, therefore, promote cartilage regeneration. However, the profile and mechanisms of E7 peptide in cartilage regeneration remain
Weili Shi +7 more
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Osterix Enhances BMSC-associated Osseointegration of Implants
Journal of Dental Research, 2009 Cellular and molecular events in osseointegration at the dental implant surface remain largely unknown. We hypothesized that bone marrow stromal cells (BMSCs) participate in this process, and that osterix (Osx) promotes implant osseointegration. To prove this hypothesis, we tracked double-labeled BMSCs in implantation sites created in nude mice ...
B, Xu +8 more
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Mitochondria on the move: BMSCs fuel AML energy [PDF]
Blood, 2017 In this issue of Blood, Marlein et al1 identify a tumor-specific NOX2-dependent transfer of mitochondria from bone marrow stromal cells (BMSCs) to acute myeloid leukemia (AML) cells via AML-derived tunneling nanotubes (see figure), supporting inhibition of NOX2 as a novel therapeutic strategy in AML.
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