Results 11 to 20 of about 38,639 (266)

Comparison of Muscle Regeneration after BMSC-Conditioned Medium, Syngeneic, or Allogeneic BMSC Injection

Cells, 2022
For many years optimal treatment for dysfunctional skeletal muscle characterized, for example, by impaired or limited regeneration, has been searched. Among the crucial factors enabling its development is finding the appropriate source of cells, which could participate in tissue reconstruction or serve as an immunomodulating agent (limiting immune ...
Barbara Świerczek-Lasek, Lukasz Tolak, Lukasz Bijoch, Marzena Stefaniuk, Patrycja Szpak, Ilona Kalaszczynska, Władysława Streminska, Maria A. Ciemerych, Karolina Archacka   +8 more
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E7 Peptide Enables BMSC Adhesion and Promotes Chondrogenic Differentiation of BMSCs Via the LncRNA H19/miR675 Axis

Bioengineering, 2023
Therapeutic strategies based on utilizing endogenous BMSCs have been developed for the regeneration of bone, cartilage, and ligaments. We previously found that E7 peptide (EPLQLKM) could enhance BMSC homing in bio-scaffolds and, therefore, promote cartilage regeneration. However, the profile and mechanisms of E7 peptide in cartilage regeneration remain
Weili Shi, Jiangyi Wu, Yanbin Pi, Xingran Yan, Xiaoqing Hu, Jin Cheng, Huilei Yu, Zhenxing Shao   +7 more
openaire   +3 more sources

Hypoxia Depletes Contaminating CD45⁺Hematopoietic Cells from Bone Marrow Stromal Cell (BMSC) Cultures: Methods for BMSC Culture Purification [PDF]

Stem Cell Research, 2020
SUMMARYCulture expanded bone marrow stromal cells (BMSCs) are easily isolated, can be grown rapidlyen masse,and contain both skeletal stem cells (SSCs) and multipotent mesenchymal progenitors (MMPs). Despite this functional heterogeneity, BMSC cultures continue to be utilized for many applications due to the lack of definitive and universally accepted ...
Guo, Wendi, Spiller, Kassandra V., Tang, Jackie, Karner, Courtney M., Hilton, Matthew J., Wu, Colleen   +5 more
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The Differentiation Balance of Bone Marrow Mesenchymal Stem Cells Is Crucial to Hematopoiesis. [PDF]

, 2018
Bone marrow mesenchymal stem cells (BMSCs), the important component and regulator of bone marrow microenvironment, give rise to hematopoietic-supporting stromal cells and form hematopoietic niches for hematopoietic stem cells (HSCs).
Li, Shengwen Calvin, Li, Zhongjun, Ran, Qian, Wu, Jiang, Xiang, Yang, Zhang, Weiwei, Zhong, Jiang F   +6 more
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Multi-Parameter Analysis of Biobanked Human Bone Marrow Stromal Cells Shows Little Influence for Donor Age and Mild Comorbidities on Phenotypic and Functional Properties [PDF]

, 2019
Heterogeneous populations of human bone marrow-derived stromal cells (BMSC) are among the most frequently tested cellular therapeutics for treating degenerative and immune disorders, which occur predominantly in the aging population.
Andrzejewska, Anastazja, Beez, Christien, Blankenstein, Antje, Catar, Rusan, Duda, Georg, Geissler, Sven, Jacobi, Dorit, Jürchott, Karsten, Kamhieh-Milz, Julian, Krüger, David, Krüger, Ulrike, Moll, Guido, Qazi, Taimoor Hasan, Reinke, Petra, Reinke, Simon, Richter, Sarina, Sass, Frauke Andrea, Schlickeiser, Stephan, Schoon, Janosch, Souidi, Naima, Streitz, Mathias, Strunk, Dirk, Zemojtel, Tomasz   +22 more
core   +1 more source

The protective mechanism of Klotho gene-modified bone marrow mesenchymal stem cells on acute kidney injury induced by rhabdomyolysis

Regenerative Therapy, 2021
Background: Studies have shown that the Klotho gene has tremendous potential for future therapeutic purposes in both acute and chronic kidney diseases (CKD).
WenHui Ni, Ying Zhang, Zhongcheng Yin
doaj   +1 more source

Human umbilical cord blood-borne fibroblasts contain marrow niche precursors that form a bone/marrow organoid in vivo [PDF]

, 2017
Human umbilical cord blood (CB) has attracted much attention as a reservoir for functional hematopoietic stem and progenitor cells, and, recently, as a source of blood-borne fibroblasts (CB-BFs). Previously, we demonstrated that bone marrow stromal cell (
Biondi, Andrea, Corsi, Alessandro, Donsante, Samantha, Pievani, Alice, Rambaldi, Benedetta, Remoli, Cristina, Riminucci, Mara, Robey, Pamela G., Sacchetti, Benedetto, Scagliotti, Valeria, Serafini, Marta, Vergani, Patrizia   +11 more
core   +2 more sources

Osterix Enhances BMSC-associated Osseointegration of Implants

Journal of Dental Research, 2009
Cellular and molecular events in osseointegration at the dental implant surface remain largely unknown. We hypothesized that bone marrow stromal cells (BMSCs) participate in this process, and that osterix (Osx) promotes implant osseointegration. To prove this hypothesis, we tracked double-labeled BMSCs in implantation sites created in nude mice ...
B, Xu, J, Zhang, E, Brewer, Q, Tu, L, Yu, J, Tang, P, Krebsbach, M, Wieland, J, Chen   +8 more
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Bone substitute effect on vascularization and bone remodeling after application of phVEGF165 transfected BMSC [PDF]

, 2012
VEGF (vascular endothelial growth factor) promotes vascularization and remodeling of bone substitutes. The aim of this study was to examine the effect of distinct resorbable ceramic carriers on bone forming capacities of VEGF transfected bone marrow ...
Beverungen, Mirjam, Fehr, Michael, Geiger, Florian, Kasten, Philip, Lorenz, Helga, Wieland, Julia   +5 more
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Injectable cartilaginous template transformed BMSCs into vascularized bone [PDF]

Scientific Reports, 2018
AbstractRegeneration of alveolar bone for dental implant remains a major issue, partifcularly for patients suffering from severe bone adsorption and irregular socket trauma. Recapitulating embryological development is becoming an attractive approach for engineer organ or three-dimensional tissues from stem cells.
Feng, Xiaoke, Li, Zhiye, Wei, Jianhua, Feng, Zhihong, Wu, Wei, Zhao, Yimin   +5 more
openaire   +2 more sources