Results 31 to 40 of about 27,592 (167)

HGF and direct mesenchymal stem cells contact synergize to inhibit hepatic stellate cells activation through TLR4/NF-kB pathway. [PDF]

PLoS ONE, 2012
AIMS: Bone marrow-derived mesenchymal stem cells (BMSCs) can reduce liver fibrosis. Apart from the paracrine mechanism by which the antifibrotic effects of BMSCs inhibit activated hepatic stellate cells (HSCs), the effects of direct interplay and ...
Pei-pei Wang, Dong-ying Xie, Xu-Jing Liang, Liang Peng, Geng-lin Zhang, Yi-nong Ye, Chan Xie, Zhi-liang Gao   +7 more
doaj   +1 more source

Mechanism research of elastic fixation promoting fracture healing based on proteomics and fracture microenvironment

Bone & Joint Research
Aims: This study aimed to demonstrate the promoting effect of elastic fixation on fracture, and further explore its mechanism at the gene and protein expression levels.
Weiyong Wu, Zhihui Zhao, Yongqing Wang, Meiyue Liu, Genbao Zhu, Lili Li   +5 more
doaj   +1 more source

Homeobox B4 gene expression is upregulated by ghrelin through PI3-kinase signaling pathway in rat’s bone marrow stromal cells

Endocrine Regulations, 2019
Objective. Ghrelin, a 28 amino acid peptide, has diverse physiological roles. Phosphatidylino-sitol-bisphosphate 3-kinase (PI3K) and mitogen-activated protein kinase (MAPK) are involved in some of the recognized actions of ghrelin. It has been shown that
Taherkhani Shokoufeh, Moradi Fatemeh, Hosseini Masoumeh, Alipour Mohsen, Feizi Hadi   +4 more
doaj   +1 more source

OSGIN2 regulates osteogenesis of jawbone BMSCs in osteoporotic rats

BMC Molecular and Cell Biology, 2022
AbstractBackgroundAugmentation of oxidative stress after estrogen deficiency leading to functional deficiency of jawbone bone marrow mesenchymal stem cells (BMSCs) causes jawbone loss in osteoporosis. OSGIN2, an oxidative stress induced factor, has been found to be associated with skeletal diseases. This study aims to investigate the function of OSGIN2
Yi Shuai, Bingyao Liu, Liang Rong, Bingyi Shao, Bo Chen, Lei Jin   +5 more
openaire   +3 more sources

Overexpression of c-Met in bone marrow mesenchymal stem cells improves their effectiveness in homing and repair of acute liver failure

Stem Cell Research & Therapy, 2017
Background Transplantation of bone marrow-derived mesenchymal stem cells (BMSCs) has emerged as a novel therapy for acute liver failure (ALF). However, the homing efficiency of BMSCs to the injured liver sites appears to be poor.
Kun Wang, Yuwen Li, Tiantian Zhu, Yongting Zhang, Wenting Li, Wenyu Lin, Jun Li, Chuanlong Zhu   +7 more
doaj   +1 more source

A brief review: the therapeutic potential of bone marrow mesenchymal stem cells in myocardial infarction

Stem Cell Research & Therapy, 2017
Myocardial infarction (MI) results in dysfunction and irreversible loss of cardiomyocytes and is among the most serious health threats today. Bone marrow mesenchymal stem cells (BMSCs), with their capacity for multidirectional differentiation, low ...
Chi Miao, Mingming Lei, Weina Hu, Shuo Han, Qi Wang   +4 more
doaj   +1 more source

New Partial Orders of Polar Codes for BMSC

2024 IEEE International Symposium on Information Theory (ISIT)
In this paper, we define partial orders (POs) of polar codes based on the Bhattacharyya parameter and the bit-error probability, respectively. These POs are applicable to arbitrary binary memoryless symmetric channel (BMSC). Leveraging the extremal inequalities of polarization transformation, we derive new POs for BMSC based on the corresponding POs ...
Liuquan Yao, Zhichao Liu, Yuan Li 0034, Huazi Zhang, Jun Wang 0062, Guiying Yan, Zhi-Ming Ma   +6 more
openaire   +3 more sources

Differentiation of rat bone marrow mesenchymal stem cell into uterine smooth muscle cell in vitro study on the mechanism

Open Life Sciences
Although bone marrow mesenchymal stem cells (BMSCs) are an important resource for tissue engineering and have been shown capable of differentiating into uterine smooth muscle cells (USMCs) to aid uterine regeneration, the precise conditions and ...
Chen ZhengYong, Liao Yuan, Yang Jing, Zeng XiaoLing   +3 more
doaj   +1 more source

The osteoinductive and osseointegration properties of decellularized extracellular matrix bone derived from different sites

Bone & Joint Research
Aims: This study aimed to examine the differences in bone induction and osseointegration performance of acellular extracellular matrix bone at different sites.
Weihua Huang, Lijing Hao, Xiayu Cai, Chujie Xiao, Huinan Yin, Weikang Xu   +5 more
doaj   +1 more source

Suppressing PLCγ1 enhances osteogenic and chondrogenic potential of BMSCs

Biochemical and Biophysical Research Communications, 2020
Phosphatidylcholine-specific phospholipase Cγ1 (PLCγ1) is involved in regulating cell metabolism. However, little is known how PLCγ1 directs BMSC differentiation. Here, we investigated the role of PLCγ1 in rat BMSC differentiation into osteoblasts and chondrocytes.
Xiaolei, Chen, Yue, Wang, Ri, Chen, Ning, Qu, Bing, Zhang, Chun, Xia   +5 more
openaire   +2 more sources