Results 51 to 60 of about 27,592 (167)

Isomangiferin promotes the migration and osteogenic differentiation of rat bone marrow mesenchymal stem cells

open access: yesOpen Life Sciences
Delayed or failed bone healing is a significant clinical challenge worldwide. Bone marrow mesenchymal stem cells (BMSCs) offer a promising approach for improving fracture healing.
Gao Bingjun   +3 more
doaj   +1 more source

Apoptosis of mesenchymal stem cells is regulated by Rspo1 via the Wnt/β-catenin signaling pathway

open access: yesChronic Diseases and Translational Medicine, 2019
Objective: The aim of this study was to investigate the effect and possible mechanism of action of roof plate-specific spondin1 (Rspo1) in the apoptosis of rat bone marrow mesenchymal stem cells (BMSCs). Methods: Osteogenic and adipogenic differentiation
Xiao-Xia Cheng   +7 more
doaj   +1 more source

Therapeutic Effects of VEGF Gene-Transfected BMSCs Transplantation on Thin Endometrium in the Rat Model

open access: yesStem Cells International, 2018
Objective. Bone mesenchymal stem cells (BMSCs) transplantation has a therapeutic effect on the thin endometrium in animal researches and clinical trials.
Zhao Jing   +4 more
doaj   +1 more source

Extracellular Vesicles Derived from H2O2-Stimulated Adipose-Derived Stem Cells Alleviate Senescence in Diabetic Bone Marrow Mesenchymal Stem Cells and Restore Their Osteogenic Capacity

open access: yesDrug Design, Development and Therapy
Yu Li,1 Guangren Yue,1 Shuying Yu,1 Zheng Liu,1 Yilin Cao,1– 3 Ximei Wang1 1Department of Plastic and Reconstructive Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People’s Republic of China; 2Shanghai Key Laboratory of Tissue
Li Y, Yue G, Yu S, Liu Z, Cao Y, Wang X
doaj  

LncRNA SNHG14 Delivered by Bone Marrow Mesenchymal Stem Cells‐Secreted Exosomes Regulates Osteogenesis and Adipogenesis in Osteoporosis by Mediating the miR‐27a‐3p/LMNB1 Axis

open access: yesKaohsiung Journal of Medical Sciences
The purpose of this study was to investigate the role of LncRNA SNHG14 delivered by bone marrow mesenchymal stem cells‐secreted exosomes (BMSC‐Exos) in osteoporosis (OP). BMSCs and BMSCs‐Exos were isolated and identified.
Jin‐Shan Tang   +4 more
doaj   +1 more source

The Effects Of Bmsc-Derived Exosomes On Oxidative Stress

open access: yesInternational Dental Journal
Aim or purpose: To explore the protective effect of exosomes from different sources of mesenchymal stem cell on BMSCs under oxidative stress. Materials and methods: BMSCs-EXO and BMSCs-EXO were extracted from BMSCs of P3-P5 generation, respectively ...
Xu Su, Ting Liu
doaj   +1 more source

FZD7 regulates BMSCs-mediated protection of CML cells

open access: yesOncotarget, 2015
Inspite of effective treatment with imatinib (IM), chronic myeloid leukemia (CML) is still an incurable disease. Some patients became refractory because of IM resistance. Bone marrow mesenchymal stem cells (BMSCs) have been implicated a role in promoting CML cells' resistance against IM treatment.
Liu, Na   +8 more
openaire   +3 more sources

Proliferation and Differentiation Potential of Bone Marrow–Derived Mesenchymal Stem Cells From Children With Polydactyly and Adults With Basal Joint Arthritis

open access: yesCell Transplantation
This study compared the proliferation and differentiation potential of bone marrow–derived mesenchymal stem cells (BMSCs) derived from infants with polydactyly and adults with basal joint arthritis.
Shih-Han Yeh   +7 more
doaj   +1 more source

Wnt3a Enhances Mesenchymal Stem Cell Engraftment and Differentiation in a Chronic Obstructive Pulmonary Disease Rat Model

open access: yesInternational Journal of COPD
Huala Wu,1,* Yulan Zhong,2,* Yangjingsi Li,3 Xiangxiang Zhou,2 Tiantian Zhao,1 Daomou Wan,1 Yuanzhe Zhu,1 Zhiyan Zhang,1 Xiaolei Li,1,4 Xin Gan1,4 1Department of Respiratory and Critical Care Medicine, Jiangxi Provincial Key Laboratory of ...
Wu H   +9 more
doaj  

B-Lymphoid Tyrosine Kinase Crosslinks Redox and Apoptosis Signaling Networks to Promote the Survival of Transplanted Bone Marrow Mesenchymal Stem Cells

open access: yesResearch
Stress-induced apoptosis presents an obstacle to bone marrow mesenchymal stem cell (BMSC) transplantation to repair steroid-induced osteonecrosis of the femoral head (SONFH).
Fei Zhang   +13 more
doaj   +1 more source

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