Results 51 to 60 of about 45,848 (279)

Lnc Tmem235 promotes repair of early steroid-induced osteonecrosis of the femoral head by inhibiting hypoxia-induced apoptosis of BMSCs

Experimental and Molecular Medicine, 2022
Bone marrow mesenchymal stem cells (BMSCs) have been used in the treatment of early steroid-induced osteonecrosis of the femoral head (SONFH). However, the hypoxic microenvironment in the osteonecrotic area leads to hypoxia-induced apoptosis of ...
Fei Zhang, Wuxun Peng, Tao Wang, Jian Zhang, Wen-tao Dong, Chuan Wang, Zhihong Xie, Hong Luo, Gang Liu   +8 more
semanticscholar   +1 more source

RETRACTED: Hepatoma Cell-Derived Extracellular Vesicles Promote Liver Cancer Metastasis by Inducing the Differentiation of Bone Marrow Stem Cells Through microRNA-181d-5p and the FAK/Src Pathway

Frontiers in Cell and Developmental Biology, 2021
Bone marrow mesenchymal stem cells (BMSCs) are beneficial to repair the damaged liver. Tumor-derived extracellular vesicles (EV) are notorious in tumor metastasis.
Huamei Wei, Huamei Wei, Jianchu Wang, Jianchu Wang, Zuoming Xu, Zuoming Xu, Wenchuan Li, Wenchuan Li, Xianjian Wu, Chenyi Zhuo, Yuan Lu, Xidai Long, Xidai Long, Qianli Tang, Qianli Tang, Jian Pu, Jian Pu   +16 more
doaj   +1 more source

METTL7A-mediated m6A modification of corin reverses bisphosphonates-impaired osteogenic differentiation of orofacial BMSCs

International Journal of Oral Science
Bisphosphonate-related osteonecrosis of jaw (BRONJ) is characterized by impaired osteogenic differentiation of orofacial bone marrow stromal cells (BMSCs).
Yizhou Jin, Xiao Han, Yuejun Wang, Z. Fan   +3 more
semanticscholar   +1 more source

Circular RNA CDR1as promotes adipogenic and suppresses osteogenic differentiation of BMSCs in steroid-induced osteonecrosis of the femoral head.

Bone, 2020
Steroid-induced osteonecrosis of the femoral head (SONFH) is a common debilitating orthopedic disease. The bone marrow mesenchymal stem cells (BMSCs) are a type of mesenchymal stem cells which play crucial roles in bone repair.
Gaoyang Chen, Qingyu Wang, Zhaoyan Li, Qiwei Yang, Yuzhe Liu, Zhenwu Du, Guizhen Zhang, Yang Song   +7 more
semanticscholar   +1 more source

A Chemical Framework for Engineering Extracellular Vesicles’ Biointerface to Advance Precision Therapeutics

Advanced Materials, EarlyView.
Extracellular vesicles (EVs) are cell‐derived nanoparticles that mediate intercellular communication through their dynamic biointerfaces. Owing to their intrinsic biological functions, EVs have emerged as promising platforms for biomedical applications.
Leila Pourtalebi Jahromi, Felix Geng, Jan‐Noël Frenzke, Gregor Fuhrmann   +3 more
wiley   +1 more source

Neurotrophin-3 Promotes the Neuronal Differentiation of BMSCs and Improves Cognitive Function in a Rat Model of Alzheimer's Disease

Frontiers in Cellular Neuroscience, 2021
Transplantation of bone marrow-derived mesenchymal stem cells (BMSCs) has the potential to be developed into an effective treatment for neurodegenerative diseases such as Alzheimer's disease (AD).
Zhongrui Yan, Xianjing Shi, Hui Wang, Cuiping Si, Qian Liu, Yifeng Du   +5 more
semanticscholar   +1 more source

Starvation‑induced NEDD4‑mediated autophagy in BMSCs

Biomedical Reports
Autophagy regulates the osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) and mediates BMSC-mediated bone remodeling under pathological conditions (such as osteoporosis and infectious bone defects). However, the regulatory mechanisms controlling autophagy in BMSCs remain unclear.
Liu, Chengyi, Zhang, Shuang, Yun, Xiaoxian, Li, Bo, Xu, Xiaomei, Lin, Fuwei   +5 more
openaire   +3 more sources

ASPH Regulates Osteogenic Differentiation and Cellular Senescence of BMSCs [PDF]

Frontiers in Cell and Developmental Biology, 2020
Osteogenesis and senescence of BMSCs play great roles in age-related bone loss. However, the causes of these dysfunctions remain unclear. In this study, we identified a differentially expressed ASPH gene in middle-aged and elderly aged groups which were obtained from GSE35955.
Hui Peng, Qi Guo, Ye Xiao, Tian Su, Tie-Jian Jiang, Li-Juan Guo, Min Wang   +6 more
openaire   +3 more sources

Biointegrated Battery‐Based Electroceuticals

Advanced Materials, EarlyView.
Biointegrated batteries go beyond passive power to serve as active therapeutic platforms for delivering programmable electrical cues and bioactive agents. This review examines their mechanisms and applications and provides a framework to guide battery‐based therapeutic design and clinical translation.
Yan Zhou, Zhilian Yue, Zhiqi Chen, Danming Chao, Xiaoteng Jia, Gordon Wallace, Caiyun Wang   +6 more
wiley   +1 more source

Differentiation of bone marrow derived mesenchymal stem cells into male germ-like cells in co-culture with testicular cells

Endocrine Regulations, 2019
Objective. Stem cell therapy, specifically, pre-induction of mesenchymal stem cells toward male germ-like cells may be useful in patients with azoospermia.
Malekmohamadi Nasim, Abdanipour Alireza, Ghorbanlou Mehrdad, Shokri Saeed, Shirazi Reza, Dimitriadis Eva, Nejatbakhsh Reza   +6 more
doaj   +1 more source