Results 21 to 30 of about 119,730 (291)

BMP4 (bone morphogenetic protein 4) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2013
Review on BMP4 (bone morphogenetic protein 4), with data on DNA, on the protein encoded, and where the gene is implicated.
Thériault, BL, Nachtigal, MW
openaire   +2 more sources

Interaction between Soluble Type I Receptor for Bone Morphogenetic Protein and Bone Morphogenetic Protein-4 [PDF]

Journal of Biological Chemistry, 1997
Bone morphogenetic proteins (BMPs) are multifunctional proteins that comprise the largest subfamily of the transforming growth factor-beta. These proteins bind to types I and II serine/threonine kinase receptors. Ligand-induced heteromeric dimerization of these receptors is the key event in initiation of biological responses. We report here large-scale
T, Natsume, S, Tomita, S, Iemura, N, Kinto, A, Yamaguchi, N, Ueno   +5 more
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Ectopic transient overexpression of facilitates BMP4-induced osteogenic transdifferentiation of human umbilical vein endothelial cells

Journal of Tissue Engineering, 2020
Limitation in cell sources for autologous cell therapy has been a recent focus in stem cell therapy and tissue engineering. Among various research advances, direct conversion, or transdifferentiation, is a notable and feasible strategy for the generation
Seung Hyun L Kim, Seunghun S Lee, Inseon Kim, Janet Kwon, Song Kwon, Taegeun Bae, Junho Hur, Hwajin Lee, Nathaniel S Hwang   +8 more
doaj   +1 more source

Bone Morphogenetic Protein 1 Prodomain Specifically Binds and Regulates Signaling by Bone Morphogenetic Proteins 2 and 4 [PDF]

Journal of Biological Chemistry, 2007
Highly purified fractions of bone extracts capable of inducing ectopic bone formation have been reported to contain peptides corresponding to the mature active regions of the TGF-beta-like bone morphogenetic proteins (BMPs) 2-7, and to the prodomain region of the metalloproteinase BMP1.
Reema, Jasuja, Gaoxiang, Ge, Nikolas G, Voss, Jamie, Lyman-Gingerich, Amanda M, Branam, Francisco J, Pelegri, Daniel S, Greenspan   +6 more
openaire   +2 more sources

Is NO the Answer? The Nitric Oxide Pathway Can Support Bone Morphogenetic Protein 2 Mediated Signaling [PDF]

, 2019
The growth factor bone morphogenetic protein 2 (BMP2) plays an important role in bone development and repair. Despite the positive effects of BMP2 in fracture healing, its use is associated with negative side effects and poor cost effectiveness, partly ...
Bormann, Nicole, Differ, Christopher, Klatte-Schulz, Franka, Knaus, Petra, Minkwitz, Susann, Wildemann, Britt   +5 more
core   +1 more source

Bone Morphogenetic Protein-4, a Novel Modulator of Melanogenesis [PDF]

Journal of Biological Chemistry, 2006
Bone morphogenetic proteins (BMPs), members of the transforming growth factor-beta family, signal in many cells including neural precursors. Two receptors, types 1 and 2, coordinately mediate BMP signaling, and type 1 receptor has two forms: A and B. Using RT-PCR we found that neural crest-derived human melanocytes express BMP receptor-1A, -1B, and -2.
Mina, Yaar, Christina, Wu, Hee-Young, Park, Izabela, Panova, Gunther, Schutz, Barbara A, Gilchrest   +5 more
openaire   +2 more sources

Addition of bone morphogenetic protein type 2 to ascorbate and β-glycerophosphate supplementation did not enhance osteogenic differentiation of human adipose-derived stem cells

Journal of Applied Oral Science, 2012
Bone morphogenetic protein type 2 (BMP-2) is a potent local factor, which promotes bone formation and has been used as an osteogenic supplement for mesenchymal stem cells.
Ariadne Cristiane Cabral Cruz, Mariana Lúcia Silva, Thiago Caon, Cláudia Maria Oliveira Simões   +3 more
doaj   +1 more source

Chondrogenesis, bone morphogenetic protein-4 and mesenchymal stem cells [PDF]

Osteoarthritis and Cartilage, 2008
As adult cartilage has very limited potential to regenerate, cartilage repair is challenging. Available treatments have several disadvantages, including formation of fibrocartilage instead of hyaline-like cartilage, as well as eventual ossification of the newly formed tissue.
Miljkovic, N.D., Cooper, G.M., Marra, K.G.   +2 more
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Influence of bone morphogenetic protein type IA receptor conditional knockout in lens on expression of bone morphogenetic protein 4 in lens

International Journal of Ophthalmology, 2015
AIM: To investigate the influence of bone morphogenetic protein type IA receptor [BMPR-IA (ALK3)] conditional knockout in lens on expression of bone morphogenetic protein 4 (BMP4) in lens during the development of the vertebrate eye.
Qi Zhao, Jiang-Yue Zhao, Jin-Song Zhang
doaj   +1 more source

Protein associated with SMAD1 (PAWS1/FAM83G) is a substrate for type I bone morphogenetic protein receptors and modulates bone morphogenetic protein signalling [PDF]

, 2014
Bone morphogenetic proteins (BMPs) control multiple cellular processes in embryos and adult tissues. BMPs signal through the activation of type I BMP receptor kinases, which then phosphorylate SMADs 1/5/8.
Campbell, David, Dingwell, Kevin S., Gourlay, Robert, Herhaus, Lina, Macartney, Thomas, Sapkota, Gopal P., Smith, James C., Vogt, Janis   +7 more
core   +3 more sources