The risk of tumor with the use of recombinant human bone morphogenetic proteins
Гений oртопедии, 2022 Introduction Bone morphogenetic proteins (BMPs) are members of a large family of growth factors known as the transforming growth factor-β (TGF-β) superfamily. BMPs are known for their ability to induce bone formation and successfully used in orthopaedic
Ural F. Mukhametov +4 more
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The effect of simvastatin on the regeneration of surgical cavities in the femurs of rabbits [PDF]
Acta Cirúrgica Brasileira, 2014 PURPOSE:To evaluate the effect of a local application of simvastatin gel in repairing bone defects in the femurs of rabbits.METHODS:Two standard surgical cavities were created in the femoral epiphysis of 18 rabbits.
José Eduardo Gomes Cardim Rosselli +5 more
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Effect of sonic hedgehog/β-TCP composites on bone healing within the critical-sized rat femoral defect [PDF]
, 2013 The creation of entirely synthetically derived bone substitute materials which are as effective as autologous bone grafts is desirable. Osteogenesis involves the concerted action of several proteins within a signaling cascade.
Flinspach, Armin Niklas +5 more
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Nuclear variants of bone morphogenetic proteins
BMC Cell Biology, 2010 Background Bone morphogenetic proteins (BMPs) contribute to many different aspects of development including mesoderm formation, heart development, neurogenesis, skeletal development, and axis formation.
Meinhart Christopher A +8 more
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Protein associated with SMAD1 (PAWS1/FAM83G) is a substrate for type I bone morphogenetic protein receptors and modulates bone morphogenetic protein signalling [PDF]
, 2014 Bone morphogenetic proteins (BMPs) control multiple cellular processes in embryos and adult tissues. BMPs signal through the activation of type I BMP receptor kinases, which then phosphorylate SMADs 1/5/8.
Campbell, David +7 more
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Adsorption and release of BMP-2 on nanocrystalline apatite-coated and uncoated hydroxyapatite/b-tricalcium phosphate porous ceramics [PDF]
, 2009 The association of bone morphogenetic proteins (BMPs) with calcium phosphate bioceramics is known to confer them osteoinductive properties. The aim of this study was to evaluate the surface properties, especially regarding recombinant human BMP-2 (rhBMP-
Alam +38 more
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Bone morphogenetic proteins: The anomalous molecules
Journal of Indian Society of Periodontology, 2013 Bone is unique of all the tissues in the vertebrate organism. When injured, it heals by formation of new bone. Bone morphogenetic proteins (BMPs) are powerful inductors of the osteogenic activity during the embryologic bone formation phase and in cases ...
Aena Pundir Jain +2 more
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Bone morphogenetic proteins: Signaling periodontal bone regeneration and repair
Journal of Pharmacy and Bioallied Sciences, 2016 Bone morphogenetic proteins (BMPs) are a group of growth factors also known as cytokines and as metabologens. Originally discovered by their ability to induce the formation of bone and cartilage, BMPs are now considered to constitute a group of pivotal ...
G Sai Anusuya +5 more
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Is NO the Answer? The Nitric Oxide Pathway Can Support Bone Morphogenetic Protein 2 Mediated Signaling [PDF]
, 2019 The growth factor bone morphogenetic protein 2 (BMP2) plays an important role in bone development and repair. Despite the positive effects of BMP2 in fracture healing, its use is associated with negative side effects and poor cost effectiveness, partly ...
Bormann, Nicole +5 more
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Generation of optimized preparations of bone morphogenetic proteins for bone regeneration [PDF]
The Ukrainian Biochemical Journal, 2016 Correction of inherited skeletal abnormalities, traumas affecting wide bone areas and non-healing fractures require efficient bone formation and regeneration.
Kh. V. Malysheva +2 more
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