Results 41 to 50 of about 1,275 (182)
Synthesis and Characterization of Gd-Functionalized B4C Nanoparticles for BNCT Applications
Life, 2023 Inorganic nanoparticles of boron-rich compounds represent an attractive alternative to boron-containing molecules, such as boronophenylalanine or boranes, for BNCT applications. This work describes the synthesis and biological activity of multifunctional
Agostina Vitali +9 more
doaj +1 more source
A Novel Boron Lipid to Modify Liposomal Surfaces for Boron Neutron Capture Therapy
Cells, 2021 Boron neutron capture therapy (BNCT) is a cancer treatment with clinically demonstrated efficacy using boronophenylalanine (BPA) and sodium mercaptododecaborate (BSH).
Makoto Shirakawa +11 more
doaj +1 more source
Boronophenylalanine for neutron capture therapy of melanoma.
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1989 Strahlenther ...
Coderre, J. A. +4 more
openaire +3 more sources
A Phase 1 trial of intravenous boronophenylalanine-fructose complex in patients with glioblastoma multiforme [PDF]
, 1996 Boron neutron capture therapy (BNCT) of glioblastoma multiforme was initially performed at the Brookhaven National Laboratory in the early 1950`s While this treatment for malignant brain tumors has continued in Japan, new worldwide interest has been ...
Joel, D. +9 more
core +1 more source
Amino Acid-Based Boron Carriers in Boron Neutron Capture Therapy (BNCT)
Pharmaceutics, 2023 Interest in the design of boronated amino acids has emerged, partly due to the utilization of boronophenylalanine (BPA), one of the two agents employed in clinical Boron Neutron Capture Therapy (BNCT).
Juulia Järvinen +3 more
doaj +1 more source
Dose Rate Effect on Cell Survival in BNCT
Current Issues in Molecular Biology, 2023 The output constancy of the accelerator used for boron neutron capture therapy (BNCT) is essential to ensuring anti-tumor efficacy and safety. BNCT as currently practiced requires a wide variety of beam quality assessments to ensure that RBE dose errors ...
Katsumi Hirose +3 more
doaj +1 more source
Poly(vinyl alcohol) boosting therapeutic potential of p-boronophenylalanine in neutron capture therapy by modulating metabolism [PDF]
, 2020 「スライムの化学」を利用した第5のがん治療法を開発 --液体のりの主成分でホウ素中性子捕捉療法の効果を劇的に向上--. 京都大学プレスリリース. 2020-01-24.How to keep boron inside cells during radiotherapy, a simple novel approach to cancer treatment. 京都大学プレスリリース.
Nomoto, Takahiro +8 more
core +1 more source
Pharmacokinetics of BPA in gliomas with ultrasound induced blood-brain barrier disruption as measured by microdialysis. [PDF]
PLoS ONE, 2014 The blood-brain barrier (BBB) can be transiently disrupted by focused ultrasound (FUS) in the presence of microbubbles for targeted drug delivery. Previous studies have illustrated the pharmacokinetics of drug delivery across the BBB after sonication ...
Feng-Yi Yang +6 more
doaj +1 more source
Biology, 2022 Boron neutron capture therapy (BNCT) is a non-invasive therapeutic technique for treating malignant tumors, however, methods to evaluate its therapeutic efficacy and adverse reactions are lacking.
Shoji Imamichi +14 more
doaj +1 more source
Molecules, 2018 Morpholine- and bis(2-methoxyethyl)amine-substituted 1,3,5-triazine derivatives containing an alkoxy-o-carborane in the 6-position of the triazine ring were successfully synthesized.
Guo Fan Jin +3 more
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