Results 61 to 70 of about 1,891 (175)
What is the role of microbial biotechnology and genetic engineering in medicine?
MicrobiologyOpen, Volume 13, Issue 2, April 2024.Microbial biotechnology, the technological application of microorganisms, has been instrumental in producing significant natural bioactive products. These include antibiotics, antifungals, anticancer drugs, antiparasitics, antivirals, immunosuppressants, toxoid vaccines, and therapeutic enzymes.
Fernando Santos‐Beneit
wiley +1 more source
Toxins, 2019 The bacterium Clostridium botulinum is the causative agent of botulism—a severe intoxication caused by botulinum neurotoxin (BoNT) and characterized by damage to the nervous system. In an effort to develop novel C.
Svetlana A. Godakova +10 more
doaj +1 more source
Peripheral nervous system and neuromuscular disorders in the emergency department: A review
Academic Emergency Medicine, Volume 31, Issue 4, Page 386-397, April 2024.Abstract Introduction Acute presentations and emergencies in neuromuscular disorders (NMDs) often challenge clinical acumen. The objective of this review is to refine the reader's approach to history taking, clinical localization and early diagnosis, as well as emergency management of neuromuscular emergencies.
Ajith Sivadasan +3 more
wiley +1 more source
A review of prevention and management of castration complications
Equine Veterinary Education, Volume 36, Issue 2, Page 97-106, February 2024.Summary Despite castration being one of the most frequently performed elective equine surgical procedures, complication rates are high and range from severe life‐threatening conditions to mild complications that are of no consequence to the horse. This article will briefly review strategies to prevent complications and surgical castration techniques ...
Christopher M. Baldwin
wiley +1 more source
Practical approach to the child presenting with acute generalised weakness
Journal of Paediatrics and Child Health, Volume 60, Issue 2-3, Page 41-46, February-March 2024.Acute generalised muscle weakness in children is a paediatric emergency with a broad differential diagnosis. A careful history and neurologic examination guides timely investigation and management. We review some of the more common causes of acute generalised muscle weakness in children, highlighting key history and examination findings, along with an ...
Rebecca Leung, Eppie M Yiu
wiley +1 more source
Journal of Immunology Research, Volume 2024, Issue 1, 2024.The advancement of genetic engineering has revolutionized the field of immunology by allowing the utilization of intrinsic antibody structures. One of the biologics that are being produced by recombinant antibody technology is single‐chain fragments variable (scFv).
Getachew Gezehagn Kussia +2 more
wiley +1 more source
Complete paralytic botulism mimicking a deep coma in a child
The Turkish Journal of Pediatrics, 2017 Botulism is a rare cause of neuroparalysis. Delay in diagnosis and treatment exerts adverse impact on mortality and morbidity. We report a child with complete flaccid paralysis followed by progression to coma-like consciousness.
Ebru Azapağası +5 more
doaj +1 more source
From Rarity to Recognition: Infantile Botulism and the Broad Spectrum of Differential Diagnoses
Case Reports in Pediatrics, Volume 2024, Issue 1, 2024.This case illustrates a 5‐week‐old girl who presented with decreased activity, decreased feeds, poor suck, weak cry, lethargy, hypotonia, and areflexia. The child was found to have infant botulism. The case demonstrates the importance of a full history and broad differential in an ill‐appearing infant.
Matthew C. Authement +4 more
wiley +1 more source
354 Case of infant botulism and review of the use of heptavalent botulinum antitoxin for treatment [PDF]
, 2021 Karen Donceras Nadua +5 more
openalex +1 more source
Intragastric Botulinum Toxin Injection and Botulism: An Alarm for Clinicians
Case Reports in Critical Care, Volume 2024, Issue 1, 2024.Clostridium botulinum produces the most potent bacterial toxin, botulinum toxin A (BTXA), which has various therapeutic and cosmetic indications. Intragastric BTXA injection is a new obesity treatment method that was argued to be safe due to the inactivation of BTXA through the liver or metabolization within the gastric wall.
Mojtaba Mojtahedzadeh +8 more
wiley +1 more source