Results 41 to 50 of about 1,608 (173)
C1GALT1 regulates integrin β1 activity and signaling.
, 2014 (a) The activity of integrin β1 was enhanced in C1GALT1 overexpressing cells. Mock and C1GALT1 transfectants were analyzed by flow cytometry with anti-integrin β1 antibody (left) or anti-activated integrin β1 (HUTS-21) antibody (right).
I-Rue Lai (608592) +7 more
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Association between C1GALT1 variants and genetic susceptibility to IgA nephropathy in Uygur
Genetics and Molecular Research, 2015 Immunoglobulin A (IgA) nephropathy (IgAN) is a common form of primary glomerulonephritis characterized by diffuse glomerular mesangial IgA1 deposition leading to mesangial proliferation and chronic glomerular inflammation. Analyses of serum IgA1 from IgAN patients revealed abnormal galactosylation of the O-linked carbohydrate moieties of IgA that may ...
W L, Li, C, Lu
openaire +2 more sources
, 2022 Additional file 6: Fig. S1. Expression of C1GALT1 in BLCA cells and tissues. A C1GALT1 mRNA expression in various stages of BLCA patients, in TCGA database.
Zhenyu Ye (4825797) +15 more
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Glycophenotypic alterations induced by Pteridium aquilinum in mice gastric mucosa: synergistic effect with Helicobacter pylori infection. [PDF]
PLoS ONE, 2012 The bracken fern Pteridium aquilinum is a plant known to be carcinogenic to animals. Epidemiological studies have shown an association between bracken fern exposure and gastric cancer development in humans.
Joana Gomes +10 more
doaj +1 more source
Protein O‐Glycosylation Shapes Lymphatic Endothelia and Lymph Node Macrophage Populations
The FASEB Journal, Volume 40, Issue 18, 30 September 2026.To study the functional roles of O‐glycans on lymphatic endothelia, we deleted Cosmc, the chaperone required for core‐1 O‐glycan synthesis. Loss of core‐1 O‐glycans entailed major changes in glycoprotein composition of lymphatic endothelial cells (LEC), including reduced podoplanin (Pdpn), CD44, and Lyve‐1, and increased ICAM‐1; reduced CD44 was caused
Jasmin Frey +11 more
wiley +1 more source
Advanced Biology, Volume 10, Issue 8, August 2026.Single‐cell glycomics reveals how epithelial–mesenchymal transition (EMT) remodels the cancer cell glycome and reshapes communication with immune cells. Emerging technologies, including scGR‐seq and GlycoChat, uncover glyco‐immune checkpoints in pancreatic cancer, highlighting glycans as active regulators of tumor–immune interactions and providing a ...
Dinh Xuan Tuan Anh, Hiroaki Tateno
wiley +1 more source
Foods, 2022 A high-fat diet (HFD) could cause gut barrier damage. The herbs in si-wu (SW) include dang gui (Angelica sinensis (Oliv.) Diels), shu di huang (the processed root of Rehmannia glutinosa Libosch.), chuan xiong (rhizome of Ligusticum chuanxiong Hort.), and
Zheng Ruan +4 more
doaj +1 more source
Advanced Science, Volume 13, Issue 27, 13 May 2026.This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang +21 more
wiley +1 more source
MGL‐Based Drug Conjugate: A Novel Glycan‐Targeting Strategy for Potential Precision Cancer Therapy
ChemistryEurope, Volume 4, Issue 5, May 2026.An engineered macrophage galactose‐type lectin (MGL)‐based conjugate (mMGL‐vcMMAE), incorporating an exposed cysteine for site‐specific drug linkage, preserves stability, binding profile, and affinity of the native MGL carbohydrate recognition domain. It also selectively targets Tn/STn‐expressing cancer cells and shows recognition of colorectal cancer ...
Carlos D. L. Lima +15 more
wiley +1 more source
C1GALT1 regulates lung metastasis of HCC cells in NOD/SCID mice.
, 2014 (a) Stable overexpression and knockdown of C1GALT1 in HCC cells. The protein expression levels of C1GALT1 were analyzed by Western blotting. (b) Effects of C1GALT1 on lung metastasis.
I-Rue Lai (608592) +7 more
core +1 more source