Results 1 to 10 of about 25,936 (261)

P-, E-, and H-cadherins differ in their relationships with coronary stenosis, cardiovascular outcomes, and unplanned recurrent revascularization [PDF]

Journal of Molecular and Cellular Cardiology Plus
Background and aims: Cadherins are adhesion proteins, and their dysregulation may result in the development of atherosclerosis, plaque rupture, or lesions of the vascular wall.
Nadezhda G. Gumanova, Dmitry K. Vasilyev, Natalya L. Bogdanova, Yaroslav I. Havrichenko, Oxana M. Drapkina   +4 more
doaj   +2 more sources

Genome-wide identification and spatiotemporal expression analysis of cadherin superfamily members in echinoderms

EvoDevo, 2023
Background Cadherins are calcium-dependent transmembrane cell–cell adhesion proteins that are essential for metazoan development. They consist of three subfamilies: classical cadherins, which bind catenin, protocadherins, which contain 6–7 calcium ...
Macie M. Chess, William Douglas, Josiah Saunders, Charles A. Ettensohn   +3 more
doaj   +1 more source

Roads to Stat3 Paved with Cadherins

Cells, 2022
The engagement of cadherins, cell-to-cell adhesion proteins, triggers a dramatic increase in the levels and activity of the Rac/Cdc42 GTPases, through the inhibition of proteasomal degradation.
Hanad Adan, Juliet Daniel, Leda Raptis
doaj   +1 more source

Cadherin switching [PDF]

Journal of Cell Science, 2008
The cadherin molecules at adherens junctions have multiple isoforms. Cadherin isoform switching (cadherin switching) occurs during normal developmental processes to allow cell types to segregate from one another. Tumor cells often recapitulate this activity and the result is an aggressive tumor cell that gains the ability to leave the site of the tumor
Margaret J, Wheelock, Yasushi, Shintani, Masato, Maeda, Yuri, Fukumoto, Keith R, Johnson   +4 more
openaire   +2 more sources

E-Cadherin Is Expressed in Epithelial Cells of the Choroid Plexus in Human and Mouse Brains

Current Issues in Molecular Biology, 2023
Evidence showing the functional significance of the choroid plexus is accumulating. Epithelial cells with tight and adherens junctions of the choroid plexus play important roles in cerebrospinal fluid production and circadian rhythm formation.
Genta Takebayashi, Yoichi Chiba, Keiji Wakamatsu, Ryuta Murakami, Yumi Miyai, Koichi Matsumoto, Naoya Uemura, Ken Yanase, Gotaro Shirakami, Yuichi Ogino, Masaki Ueno   +10 more
doaj   +1 more source

Autoregulation of E-cadherin expression by cadherin–cadherin interactions [PDF]

The Journal of Cell Biology, 2003
Transcriptional repression of E-cadherin, characteristic of epithelial to mesenchymal transition, is often found also during tumor cell invasion. At metastases, migratory fibroblasts sometimes revert to an epithelial phenotype, by a process involving regulation of the E-cadherin–β-catenin complex. We investigated the molecular basis of this regulation,
Maralice Conacci-Sorrell, Inbal Simcha, Tamar Ben-Yedidia, Janna Blechman, Pierre Savagner, Avri Ben-Ze'ev   +5 more
openaire   +1 more source

Extracellular domains of E-cadherin determine key mechanical phenotypes of an epithelium through cell- and non-cell-autonomous outside-in signaling.

PLoS ONE, 2021
Cadherins control intercellular adhesion in most metazoans. In vertebrates, intercellular adhesion differs considerably between cadherins of type-I and type-II, predominantly due to their different extracellular regions.
Darwesh Mohideen Kaderbatcha Aladin, Yeh Shiu Chu, Shuo Shen, Robert Charles Robinson, Sylvie Dufour, Virgile Viasnoff, Nicolas Borghi, Jean Paul Thiery   +7 more
doaj   +1 more source

Association of DNA Methylation Patterns in 7 Novel Genes With Ischemic Stroke in the Northern Chinese Population

Frontiers in Genetics, 2022
Background: Ischemic stroke is a highly complex disorder. This study aims to identify novel methylation changes in ischemic stroke.Methods: We carried out an epigenome-wide study of ischemic stroke using an Infinium HumanMethylation 850K array (cases ...
Hongwei Sun, Jia Xu, Bifeng Hu, Yue Liu, Yun Zhai, Yanyan Sun, Hongwei Sun, Fang Li, Jiamin Wang, Anqi Feng, Ying Tang, Jingbo Zhao   +11 more
doaj   +1 more source

Catenin signaling controls phrenic motor neuron development and function during a narrow temporal window

Frontiers in Neural Circuits, 2023
Phrenic Motor Column (PMC) neurons are a specialized subset of motor neurons (MNs) that provide the only motor innervation to the diaphragm muscle and are therefore essential for survival.
Alicia N. Vagnozzi, Matthew T. Moore, Raquel López de Boer, Aambar Agarwal, Niccolò Zampieri, Lynn T. Landmesser, Polyxeni Philippidou   +6 more
doaj   +1 more source

Expression of classic cadherins and δ-protocadherins in the developing ferret retina

BMC Neuroscience, 2009
Background Cadherins are a superfamily of calcium-dependent adhesion molecules that play multiple roles in morphogenesis, including proliferation, migration, differentiation and cell-cell recognition.
Krishna-K K, Etzrodt Johannes, Redies Christoph   +2 more
doaj   +1 more source