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Trichomonas vaginalis is an extracellular protozoan parasite that causes human trichomoniasis, a sexually transmitted infection (STI) that affects approximately 270 million people worldwide. The phenomenon of T. vaginalis adhesion to inert substrates has
Sharmila Fiama das Neves Ortiz +3 more
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Restricted expression of classic cadherins in the spinal cord of the chicken embryo
Classic cadherins belong to the family of cadherin genes and play important roles in neurogenesis, neuron migration and axon growth. In the present study, we compared the expression patterns of 10 classic cadherins (Cdh2, Cdh4, Cdh6, Cdh7, Cdh8, Cdh9 ...
Juntang eLin +4 more
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Cadherin Signaling in Cancer: Its Functions and Role as a Therapeutic Target
Cadherin family includes lists of transmembrane glycoproteins which mediate calcium-dependent cell-cell adhesion. Cadherin-mediated adhesion regulates cell growth and differentiation throughout life.
Weina Yu +12 more
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Adhesion molecules in Wilms tumor (part I) [PDF]
Adhesion molekues are glicoprotees which have extracellular, transmembranous and intracytoplasmatic part. They show their basic role is in cell interaction in the tissue on one side and between cells and matrix on the other side.
Basta-Jovanović Gordana M. +2 more
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Evolutionary origin of type IV classical cadherins in arthropods
Background Classical cadherins are a metazoan-specific family of homophilic cell-cell adhesion molecules that regulate morphogenesis. Type I and type IV cadherins in this family function at adherens junctions in the major epithelial tissues of ...
Mizuki Sasaki +2 more
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Cadherin Expression and EMT: A Focus on Gliomas
Cadherins are calcium-binding proteins with a pivotal role in cell adhesion and tissue homeostasis. The cadherin-dependent mechanisms of cell adhesion and migration are exploited by cancer cells, contributing to tumor invasiveness and dissemination.
Carolina Noronha +6 more
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Cadherins and catenins in cancer: connecting cancer pathways and tumor microenvironment
Cadherin-catenin complexes are integral components of the adherens junctions crucial for cell-cell adhesion and tissue homeostasis. Dysregulation of these complexes is linked to cancer development via alteration of cell-autonomous oncogenic signaling ...
Wan-Hsin Lin +2 more
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The role of the cell adhesion molecules (integrins / cadherins) in prostate cancer
During prostate carcinogenesis the cellular adhesion molecules, i.e.; integrins and cadherins mediate aberrant interactions between glandular epithelial cells and the extracellular matrix. Several integrin α subunits are down-regulated, while β
Alexandros Drivalos +4 more
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Recurrent chronic mucosal inflammation, a characteristic of inflammatory bowel diseases (IBD), perturbs the intestinal epithelial homeostasis resulting in formation of mucosal wounds and, in most severe cases, leads to colitis-associated colon cancer ...
Nayden G. Naydenov +9 more
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Coordinated cadherin functions sculpt respiratory motor circuit connectivity
Breathing, and the motor circuits that control it, is essential for life. At the core of respiratory circuits are Dbx1-derived interneurons, which generate the rhythm and pattern of breathing, and phrenic motor neurons (MNs), which provide the final ...
Alicia N Vagnozzi +10 more
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