Results 21 to 30 of about 25,936 (261)

A Review on Host-Leptospira Interactions: What We Know and Future Expectations

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Leptospirosis is a widespread zoonosis caused by pathogenic Leptospira spp. It is considered a neglected infectious disease of human and veterinary concern.
Brenda B. Daroz   +15 more
doaj   +1 more source

Computer simulations of cell sorting due to differential adhesion.

open access: yesPLoS ONE, 2011
The actions of cell adhesion molecules, in particular, cadherins during embryonic development and morphogenesis more generally, regulate many aspects of cellular interactions, regulation and signaling.
Ying Zhang   +4 more
doaj   +1 more source

Neural crest cell-placodal neuron interactions are mediated by Cadherin-7 and N-cadherin during early chick trigeminal ganglion assembly [version 1; peer review: 1 approved, 2 approved with reservations]

open access: yesF1000Research, 2022
Background: Arising at distinct positions in the head, the cranial ganglia are crucial for integrating various sensory inputs. The largest of these ganglia is the trigeminal ganglion, which relays pain, touch and temperature information through its three
Chyong-Yi Wu   +2 more
doaj   +1 more source

Anticancer Activity of Holothuria Leucospilota-Derived Saponin on MKN45 Gastric Cancer Cell via Upregulation of CDH1 Hub Gene [PDF]

open access: yesMiddle East Journal of Cancer
Background: The treatment of gastric cancer (GC) is still quite challenging. Yet, marine invertebrates have been found to produce a wide range of anticancer bioactive compounds that show promise in fighting cancer.
Khadijeh Sadegh   +3 more
doaj   +1 more source

Holding it together: when cadherin meets cadherin

open access: yesBiophysical Journal, 2021
Intercellular adhesion is the key to multicellularity, and its malfunction plays an important role in various developmental and disease-related processes. Although it has been intensively studied by both biologists and physicists, a commonly accepted definition of cell-cell adhesion is still being debated.
Arslan, F.N.   +3 more
openaire   +3 more sources

Cell Adhesion Molecules in Normal Skin and Melanoma

open access: yesBiomolecules, 2021
Cell adhesion molecules (CAMs) of the cadherin, integrin, immunoglobulin, and selectin protein families are indispensable for the formation and maintenance of multicellular tissues, especially epithelia.
Cian D’Arcy, Christina Kiel
doaj   +1 more source

E-cadherin binds to desmoglein to facilitate desmosome assembly

open access: yeseLife, 2018
Desmosomes are adhesive junctions composed of two desmosomal cadherins: desmocollin (Dsc) and desmoglein (Dsg). Previous studies demonstrate that E-cadherin (Ecad), an adhesive protein that interacts in both trans (between opposing cells) and cis (on the
Omer Shafraz   +6 more
doaj   +1 more source

Impact of Ki-67 and E-cadherin expression on lymphovascular invasion in upper urinary tract urothelial carcinoma [PDF]

open access: yesVojnosanitetski Pregled, 2015
Bacground/Aim. Upper urinary tract urothelial carcinoma (UUT-UC) constitutes 5% of malignant neoplasms arising from transitional epithelium, but is more invasive than bladder cancer.
Stojnev Slavica   +7 more
doaj   +1 more source

Cadherins as Matchmakers [PDF]

open access: yesNeuron, 2011
Cadherins implement afferent-target matching in invertebrates, but proof for this concept in mammalian circuits has remained elusive. Two new studies in this issue of Neuron show that cadherin-6 mediates retinal ganglion cell target selection and that cadherin-9 promotes synapse specificity in the hippocampus.
Rebsam, Alexandra, Mason, Carol A.
openaire   +2 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

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