Results 41 to 50 of about 65,722 (350)

Holding it together: when cadherin meets cadherin

open access: yesBiophysical Journal, 2021
Intercellular adhesion is the key to multicellularity, and its malfunction plays an important role in various developmental and disease-related processes. Although it has been intensively studied by both biologists and physicists, a commonly accepted definition of cell-cell adhesion is still being debated.
Arslan, F.N.   +3 more
openaire   +3 more sources

P-Cadherin Regulates Intestinal Epithelial Cell Migration and Mucosal Repair, but Is Dispensable for Colitis Associated Colon Cancer

open access: yesCells, 2022
Recurrent chronic mucosal inflammation, a characteristic of inflammatory bowel diseases (IBD), perturbs the intestinal epithelial homeostasis resulting in formation of mucosal wounds and, in most severe cases, leads to colitis-associated colon cancer ...
Nayden G. Naydenov   +9 more
doaj   +1 more source

Zebrafish teeth as a model for repetitive epithelial morphogenesis: dynamics of E-cadherin expression [PDF]

open access: yes, 2010
Background: The development of teeth is the result of interactions between competent mesenchyme and epithelium, both of which undergo extensive morphogenesis.
Huysseune, Ann   +3 more
core   +3 more sources

Coordinated cadherin functions sculpt respiratory motor circuit connectivity

open access: yeseLife, 2022
Breathing, and the motor circuits that control it, is essential for life. At the core of respiratory circuits are Dbx1-derived interneurons, which generate the rhythm and pattern of breathing, and phrenic motor neurons (MNs), which provide the final ...
Alicia N Vagnozzi   +10 more
doaj   +1 more source

E-cadherin binds to desmoglein to facilitate desmosome assembly

open access: yeseLife, 2018
Desmosomes are adhesive junctions composed of two desmosomal cadherins: desmocollin (Dsc) and desmoglein (Dsg). Previous studies demonstrate that E-cadherin (Ecad), an adhesive protein that interacts in both trans (between opposing cells) and cis (on the
Omer Shafraz   +6 more
doaj   +1 more source

A Review on Host-Leptospira Interactions: What We Know and Future Expectations

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Leptospirosis is a widespread zoonosis caused by pathogenic Leptospira spp. It is considered a neglected infectious disease of human and veterinary concern.
Brenda B. Daroz   +15 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Neural crest cell-placodal neuron interactions are mediated by Cadherin-7 and N-cadherin during early chick trigeminal ganglion assembly [version 1; peer review: 1 approved, 2 approved with reservations]

open access: yesF1000Research, 2022
Background: Arising at distinct positions in the head, the cranial ganglia are crucial for integrating various sensory inputs. The largest of these ganglia is the trigeminal ganglion, which relays pain, touch and temperature information through its three
Chyong-Yi Wu   +2 more
doaj   +1 more source

Differential Displacement of Classical Cadherins by VE-Cadherin [PDF]

open access: yesCell Communication & Adhesion, 2002
VE-cadherin is an endothelial cell-specific, type II classical cadherin that plays an important role in permeability, vasculogenesis, and vascular remodeling. Endothelial cells express equal levels of VE- and N-cadherin; VE-cadherin is present injunctions while N-cadherin is diffusely expressed over the surface of the cell.
Meena, Jaggi   +2 more
openaire   +2 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

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